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JAX® Mice and Services news

May 27

Desktop Wallpaper Calendars for June 2015
Free downloadable image for your desktop or phone

May 27

Oxytocin Primes the Maternal Left Brain in Mice

New York University researchers have identified oxytocin-responsive neurons in the left auditory cortex that mediate maternal pup retrieval.

May 27

Generating New Self-Specific Treg Cells to Target Autoimmune Disorders

Deregulated, impaired Treg cells allow uncontrolled destruction of healthy tissues by cytotoxic T cells in many common autoimmune disorders.

May 18

Reduced prices on JAX® Mice strains—Special J offers
Save 25% off select strains of JAX® Mice, while supplies last

May 13

Modeling Antibody-Induced Cytokine Storm in Hu-PBMC NSG™ Mice
Therapeutic antibodies (Abs) are being used clinically to treat cancer.  For many patients receiving these compounds, a potentially life- threatening condition called cytokine storm or cytokine release syndrome (CRS) can render these treatments unfeasible.

May 13

RBM3 Mediates Protective Effects of Cooling on Neurodegeneration
A new study in Nature (Peretti et al. 2015) demonstrates the protective effects of the cold-shock protein RBM3 on neurodegeneration in the 5XFAD mouse model of Alzheimer’s disease and a mouse model for prion disease.  The data suggests that modulating cold-shock protein pathways offers a potential and novel new therapeutic approach for preventing and treating neurodegenerative diseases.

April 29

Repurposing Viagra Reverses Peripheral Neuropathy in Diabetic Mice
A recent report in PLoS One (Wang et al. 2015) demonstrates that sildenafil (Viagra®) treatment significantly alleviates diabetic peripheral neuropathy and neurovascular dysfunction in mice with long-term diabetes.

April 29

Psychiatric Disorders in Offspring Linked to Asthmatic Mothers
A recent study (Schwartzer et al. 2015) in mice examining the developmental and behavioral differences between offspring born to asthmatic and non-asthmatic mothers draws an important link between inflammatory signaling in utero and its effect on neurological development.

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