List of agents monitored

"A" List agents

Mouse pathogens

These organisms are pathogenic for mice and/or have a significant potential for interference with research. If any of these organisms are found in any JAX® Mice strain, all shipments from the room are suspended and customers are notified.

Viruses

Ectromelia virus (agent causing mouse pox)

Mouse hepatitis virus (MHV)

GDVII (Theiler's mouse encephalomyelitis) virus

Mouse parvovirus (MPV)

Hantaan virus (Hantavirus)*†

Mouse thymic virus (MTV)

K virus

Pneumonia virus of mice (PVM)

Lactic dehydrogenase elevating virus

Polyoma virus

Lymphocytic choriomeningitis (LCMV)†

Reovirus 3 (REO 3)

Mouse minute virus (MMV) (formerly MVM)

Rotavirus (Epizootic diarrhea of infant mice [EDIM])

Mouse adenovirus (MAV)

Sendai virus

Mouse cytomegalovirus (MCMV)

 

*Neither wild nor laboratory mice of the genus Mus are natural hosts for hanta viruses; however, JAX® Mice are monitored as a precaution due to the zoonotic potential of these agents.

† Zoonotic agents

Bacteria & mycoplasma

CAR bacillus

Mycoplasma pulmonis

Citrobacter rodentium (Citrobacter freundii 4280)

Salmonella spp.

Clostridium piliforme

Streptobacillus moniliformis

Parasites

Although most of these organisms have limited potential to cause disease or interfere with research, they are unacceptable in most facilities. If any of these organisms are found, all shipments from the room are suspended and customers are notified.

Encephalitozoon cuniculi

Pinworms

Fleas, fur mites, lice

Roundworms and other helminths

Follicle mites

Tapeworms

"B" List agents

Opportunistic organisms

These organisms are generally recognized as opportunistic pathogens that may complicate disease or interfere with research under certain circumstances, e.g., immunodeficient mice.  They are not tolerated in any Production area – positive results trigger a clinical investigation designed to eliminate all infected mice.  Shipping from the area is not stopped.

Bordetella bronchiseptica

Pneumocystis carinii**

Corynebacterium kutscheri

Pseudomonas spp.

Helicobacter spp.

Staphylococcus aureus

Klebsiella pneumoniae

Streptococcus spp.

Murine norovirus (MNV)

Opportunistic protozoa (e.g., Giardia, Spironucleus)

Pasteurella pneumotropica

 

** Pneumocystis carinii monitoring is conducted on severely immunodeficient mice only and performed only if severely immunodeficient mice are housed in the room.

Other (nonpathogenic) organisms

These organisms are generally viewed as normal flora of mice or as exogenous microorganisms with little or no potential to cause disease or interfere with research. If any of these organisms are found in any JAX® Mice strain, the finding is noted in this report, but shipments are not suspended.

Klebsiella spp. other than K. pneumoniae

Nonpathogenic protozoa (e.g., trichomonads)