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JAX® Mice and Services news

May 27

Desktop Wallpaper Calendars for June 2015
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May 27

Oxytocin Primes the Maternal Left Brain in Mice

New York University researchers have identified oxytocin-responsive neurons in the left auditory cortex that mediate maternal pup retrieval.

May 27

Generating New Self-Specific Treg Cells to Target Autoimmune Disorders

Deregulated, impaired Treg cells allow uncontrolled destruction of healthy tissues by cytotoxic T cells in many common autoimmune disorders.

May 18

Reduced prices on JAX® Mice strains—Special J offers
Save 25% off select strains of JAX® Mice, while supplies last

May 13

Modeling Antibody-Induced Cytokine Storm in Hu-PBMC NSG™ Mice
Therapeutic antibodies (Abs) are being used clinically to treat cancer.  For many patients receiving these compounds, a potentially life- threatening condition called cytokine storm or cytokine release syndrome (CRS) can render these treatments unfeasible.

May 13

RBM3 Mediates Protective Effects of Cooling on Neurodegeneration
A new study in Nature (Peretti et al. 2015) demonstrates the protective effects of the cold-shock protein RBM3 on neurodegeneration in the 5XFAD mouse model of Alzheimer’s disease and a mouse model for prion disease.  The data suggests that modulating cold-shock protein pathways offers a potential and novel new therapeutic approach for preventing and treating neurodegenerative diseases.

April 29

Repurposing Viagra Reverses Peripheral Neuropathy in Diabetic Mice
A recent report in PLoS One (Wang et al. 2015) demonstrates that sildenafil (Viagra®) treatment significantly alleviates diabetic peripheral neuropathy and neurovascular dysfunction in mice with long-term diabetes.

April 29

Psychiatric Disorders in Offspring Linked to Asthmatic Mothers
A recent study (Schwartzer et al. 2015) in mice examining the developmental and behavioral differences between offspring born to asthmatic and non-asthmatic mothers draws an important link between inflammatory signaling in utero and its effect on neurological development.

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