JAX® NOTES Summer 2006, No. 502
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In this issue...
The Importance of Genetic Background in Mouse-based Biomedical Research
You may occasionally see a cautionary note on strain data sheets of some of our JAX® Mice models. We include this note because the variety of genetic backgrounds and the mutations characterized and published on them are continually increasing.
Characterization of DIO Model is Refined
The C57BL6J (B6) male mouse is the most commonly used model of diet-induced obesity (DIO). Male B6 mice have many of the same obesity phenotypes as do humans, including visceral adioposity, insulin resistance, hyperinsulinemia, hyperleptinemia, and leptin resistance.
Newly Available JAX® GEMM® Strains
See a list of newly available JAX® GEMM® Strains.
New JAX® Mice Database Goes Live
On Sunday, March 5, a new database began serving the JAX® Mice Web site.
How to Submit Data to the MGI Database
The Mouse Genome Informatics (MGI) database is the authoritative source for mouse gene, allele, and strain nomenclature, and gene associates to the Gene Ontology and Mammalian Phenotype Ontology.
Jackson Laboratory Awarded $15.1M Federal Grant
Under a "National Centers for Systems Biology" program, the National Institute of General Medical Sciences (NIGMS) has awarded a five-year grant for $15.073,585 to a team of Jackson Laboratory researchers and collaborators who are using a new systems approach to study the genetics of health and disease.
Courses and Conferences
A partial list of upcoming courses, workshops, and meetings sponsored by The Jackson Laboratory.
New Infectious Disease Resource Manual Available
Staff at The Jackson Laboratory recently compiled a new resource manual entitled "Infectious Disease Research and the Laboratory Mouse: A Jackson Laboratory Resource Manual."