New: JAX® QTL Mapping Analysis Service Launches
JAX® NOTES Issue 511, Fall 2008
JAX® Services is now offering QTL Mapping Analysis Services. Service options include one- and/or two-dimensional genome-wide scans to identify major QTLs and QTL interactions and fit multiple regression models for candidate QTLs and covariates, and the generation of scan plots, confidence intervals, effect plots, and a final report. Genome scans are performed with JAX's panel of over 2,100 validated single nucleotide polymorphic (SNP) markers. Statistical analyses were developed by JAX scientists (Broman et al. 2003; Doerge and Churchill 1996; Lander and Kruglyak 1995; Sen and Churchill 2001).
For all the details (including depth-of-analysis and pricing options), visit www.jax.org/jaxservices/qtl, or contact us at 1-800-422-6423, 1-207-288-5845, or jaxservices@jax.org.
References
(Authors in bold are Jackson Laboratory scientists)
Broman KW, Wu H, Sen S, Churchill GA. 2003. R/qtl: QTL mapping in experimental crosses. Bioinformatics 19:889-90.
Doerge RW, Churchill GA. 1996. Permutation tests for multiple loci affecting a quantitative character. Genetics 142:285-94.
Lander E, Kruglyak L. 1995. Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nat Genet 11:241-7.
Sen S, Churchill GA. 2001. A statistical framework for quantitative trait mapping. Genetics 159:371-87.
