JAX® NOTES Issue 511, Fall 2008

Download JAX Notes, Fall 2008, No. 511 as a printable PDF document

In this issue...

Cryopreservation and recovery: Critical components in disaster preparedness for mouse-based research

Hurricane Katrina. The California fires. The Midwest floods. The China earthquakes. Are your years of research and valuable research mice safe from such disasters? Have you considered cryopreserving your research stocks — in several locations?

NEW: Special J Offers - savings on selected JAX® Mice strains

The Jackson Laboratory routinely maintains some mouse strains in colonies large enough to facilitate the discovery of spontaneous mutations. This practice occasionally results in excess mice.

Jackson Laboratory employees support Red Cross relief effort for victims of China earthquakes

In the aftermath of devastating earthquakes that left millions of people in China without food or shelter, a group of Jackson Laboratory employees came together to help, donating nearly $10,000 to the Red Cross relief effort.

NEW: Volume pricing program for select JAX® Mice strains

Do you anticipate ordering large quantities of C57BL/6J (000664) or BALB/cJ (000651) mice in the near future? If so, we have some good news!

Two New JAX Regional Representatives

New to The Jackson Laboratory are Regional Representatives Rick Huntress, for the upper Northeastern U.S., and Rebekah Harden, for the Southeastern U.S.

caBIG™ at The Jackson Laboratory offers innovative tools to further cancer research

Designated as a Cancer Center since 1983 by the National Cancer Institute (NCI), The Jackson Laboratory actively participates in NCI’s cancer Biomedical Information Grid (caBIG™) initiative.

MGI Gene Expression Database (GXD) updated

Expression data from the Gene Expression Database (GXD) project is now seamlessly integrated into the Mouse Genome Informatics website.

Improved: Strain Data Sheets for JAX® Mice

Find the information you need about JAX® Mice quickly! Move from one type of information to another and back with ease! It’s all possible, thanks to an improved tab-formatted redesign of JAX® Mice Strain Data Sheets.

TALLYHO, a new polygenic model of type 2 diabetes

TALLYHO!! Most people associate this word with the cry used in the British Isles to excite and prompt fox hunting hounds to chase after their quarry. At JAX, however, TALLYHO has an entirely different meaning.

NOD scid gamma (NSG): official common name for the NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ JAX® Mice strain

Many of our JAX® mice are not commonly referred to by their official strain names. Over time, they acquire common names, such as "NOD scid", "Black six" or "B6", "BALB", and "B6 Rag".

“Healer” JAX® Mice strain can regenerate cartilage

Someday, revolutionary treatments for human knee, shoulder, and hip injuries may be the result of research conducted with one of our JAX® Mice strains.

Ifng-deficient BALB/cJ mice play key role in lymphoma vaccine

With the help of JAX® Mice strain C.129S7(B6)-Ifngtm1Ts/J (002286), an interferon gamma (Ifng)-deficient mouse with a BALBc/J (000651) background, scientists recently moved one step closer to developing a vaccine against anaplastic large cell lymphoma (ALCL).

New body weight Information for B6.V-Lepob/J and BKS.Cg-m +/+ Leprdb/J strains

New body weight information for JAX® Mice strains B6.V-Lepob/J (000632) and BKS.Cg-m +/+ Leprdb/J (000642)

Influence of Nnt alleles on DIO in C57BL/6 JAX® Mice

If you research diabetes and/or obesity you may be wondering if the null mutation of the NAD nucleotide transhydrogenase (Nnt) gene (Toye et al. 2005; Freeman et al. 2006) in JAX® Mice strain C57BL/6J (B6/J, 000664) affects its responsiveness to diet-induced obesity (DIO).

Newly Available JAX® Mice Strains

Newly Available JAX® Mice Strains

New: JAX® QTL Mapping Analysis Service Launches

JAX® Services is now offering QTL Mapping Analysis Services. Service options include one- and/or two-dimensional genome-wide scans to identify major QTLs and QTL interactions and fit multiple regression models for candidate QTLs and covariates, and the generation of scan plots, confidence intervals, effect plots, and a final report.

JAX® Histology Services Expands

JAX® Histology Services specializes in collecting, fixing, staining, sectioning, and embedding mouse tissues for biomedical researchers. It is an excellent option for researchers who don’t have the resources to perform these operations themselves.

New study directors at Jackson Laboratory—West

Two new study directors recently joined the JAX® In Vivo Services team at our California facility.

The Jackson Laboratory enters partnership to fight Friedreich’s Ataxia

Early in 2008, the Friedreich’s Ataxia Research Alliance (FARA) engaged The Jackson Laboratory to discuss opportunities to have Friedrich’s Ataxia (FA) mouse models brought into JAX and made available to the research community.

Dr. Victor McKusick, “Father of Medical Genetics”, succumbs to cancer at age 86

Dr. Victor McKusick, Johns Hopkins University physician known as “The Father of Medical Genetics”, died July 22, 2008, at the age of 86.

Oxford English Dictionary credits word “genomics” to Jackson Laboratory scientist

The Oxford English Dictionary has credited the word “genomics” to retired Jackson Laboratory geneticist and Bangor native Dr. Thomas H. Roderick. The dictionary defines the term as “the scientific study of genomes . . .

Colony Management: Principles and Practices

Colony Management: Principles and Practices

Visit The Jackson Laboratory on the Road

Representatives of The Jackson Laboratory will be attending the following meetings and conferences during the remainder of 2008.

Updated: JAX® Most Popular Strains Catalog

Request a complimentary copy of our expanded JAX® Most Popular Strains Catalog (2008 edition) — chock full of information about our 41 most widely used JAX® Mice strains.