Coming Soon: CNV Analysis Service
JAX® NOTES Issue 513, Spring 2009
The analysis of Copy Number Variations (CNVs) is an important service that The Jackson Laboratory hopes to offer in the near future. The Mouse Diversity Genotyping Array contains over 900,000 invariant genomic probes (IGPs) to enable the detection of copy number variations. Currently, IGPs remain an experimental research application of this array. They were computationally mined from the NCBI Build 36 genome assembly of C57BL/6J and genomic sequence data from M. m. molossinus (MSM/Ms), an inbred strain derived from the Japanese wild mouse.
93% of Ensembl-annotated exons are represented with at least one IGP. To determine relative CNVs, IGP probe intensities can be compared among separate samples.
