JAX® NOTES Issue 513, Spring 2009
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Download JAX NOTES, Spring 2009, No. 513 as a printable PDF document |
In this issue...
The Jackson Laboratory—West: New Sacramento facility open for business
Expanded and improved service for West Coast researchers is here. Our brand new facility in Sacramento, Calif., The Jackson Laboratory—West, is now open for business.
JAX® In Vivo Core Services Comprehensive and customizable efficacy testing platforms
The new facility will include expanded research space for JAX® In Vivo Core Services.
JAX® In Vivo Cancer Services
Program Director Neal Goodwin, Ph.D., is experienced in preclinical drug development.
Study Director Sandra Biroc, Ph.D., oversees xenograft, orthotopic and metastatic cancer models projects.
JAX® Services Cancer Program
JAX® In Vivo Cancer Services offers xenograft services (NCI-60 panel; WSU-DLCL2 NHL), orthotopic models (featuring biophotonic imaging), teratoma pluripotency testing, endogenous models and humanized primary cancer clinical trial isolates (including collaborative predictive medicine platforms).
Expanded customer service and technical support hours
Customer Service and Technical Support staff are now available to accept orders and answer questions between 5 AM and 5 PM Pacific Time (8 AM and 8 PM Eastern Time), Monday through Friday.
Copy number variations (CNVs): a new layer of genomic complexity revealed
With the completion of the human genome sequence and that of other organisms used to model human disease, it appeared that the greatest discoveries of the genome were behind us.
JAX unveils new "Do-it-yourself" Sperm Cryo Kit
The JAX® Sperm Cryo Kit is a new approach to sperm cryopreservation: it gives you control over the first steps of the process yet preserves your access to JAX's robust quality testing and cryo storage protocols.
New JAX® Pathology Service
Need experienced pathologists to support your mouse-based research? Our new JAX® Pathology Service may be just what you need.
New JAX® Mouse Diversity Genotyping Array Service
JAX® Services is now offering a revolutionary genotyping service featuring the innovative Mouse Diversity Genotyping Array produced by Affymetrix, a leading source of genetic technologies.
Coming Soon: CNV Analysis Service
The analysis of Copy Number Variations (CNVs) is an important service that The Jackson Laboratory hopes to offer in the near future.
JAX® Cells, Tissues & Products: New Offerings
JAX® Mouse Embryonic Fibroblasts (JAX® MEFs) and JAX® Mouse Embryonic Stem Cells (JAX® mES cells)
JAX® Mice help reveal potential health benefits of resveratrol
What do red wine, soybeans, pomegranates, mulberries, red grapes and peanuts have in common?
Pleiades Promoter Project mice shine at The Jackson Laboratory
In Greek mythology, the Pleiades cluster represents the seven daughters of the Titan god, Atlas. Analogously, the Pleiades Promoter Project is a "daughter" of the Mouse Atlas Project, a scientific resource that provides expression maps of approximately 20,000 genes in the mouse.
Newly Available JAX® Mice strains
A listing of 13 newly available JAX® Mice strains.
JAX-engineered NSG mouse, an innovative cancer research tool
In the winter issue of JAX® NOTES, we explained how the NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ (005557) mouse, nicknamed "NSG" (for NOD scid gamma), is enabling cutting-edge HIV research (Kumar et al. 2008). In this issue, we call attention to the superior ability of this mouse to engraft human cells and tissues. As a result, new insights into the pathophysiology and development of therapies for several cancer types have been unveiled.
New JAX cancer researcher studies heat shock response
The most recent addition to The Jackson Laboratory's scientific staff, cancer researcher Chengkai Dai, M.D., Ph.D, is armed with a mission — to better understand the heat shock or stress response — a highly conserved adaptive mechanism that normally protects healthy cells from environmental stresses but sometimes changes allegiance to protect cancer cells.
JAX® ocular research produces eye-catching results
It's hard to imagine a 750+ page book written on the mouse eye, but that's exactly the subject matter of "Eye, retina and visual system of the mouse" (edited by Leo M. Chalupa and Robert W. Williams, MIT Press, Cambridge, MA)
Number of cryopreserved JAX® Mice strains grows by 800+
Online exclusive article
Over the last two years, over 800 JAX® Mice strains have been added to the JAX Repository, expanding its already vast selection of unique genetically engineered mouse strains by 30%.
JAX Professor Gridley awarded nearly $2 million NIH grant
Online exclusive article
The Eunice Kennedy Shriver National Institute of Child Health & Human Development awarded Professor Thomas Gridley, Ph.D., a five-year grant
JAX hires new computer scientist
Online exclusive article
Overwhelmed by the exponentially increasing volume of biological information hidden in computer databases? Help is on the way in the form of new JAX computational biologist Matthew Hibbs, Ph.D.
Collaborative Cross to improve systems genetics analysis
Online exclusive article
Genetic analysis is experiencing a new dawn — systems genetics, the study of the interactions among the genes in a biochemical pathway. A relatively new concept, systems genetics will help scientists better understand how genes function in the context of the entire biochemical pathway to which they belong.
MGI releases a new and more powerful Quick Search Tool
Online exclusive article
Mouse Genomie Informatics (MGI) has released a new and more powerful version of its Quick Search Tool.
JAX Professor Ken Paigen receives Fulbright Award
Online exclusive article
Insatiably curious and ever-ready to explore new scientific frontiers, Professor Kenneth Paigen, Ph.D., Executive Research Fellow at JAX, spent the month of November at France's Pasteur Institute collaborating with other researchers to better understand the processes that lead to genetic diversity.
JAX partners in international mouse sequencing project
Online exclusive article
In 2000, the human genome sequence was completed. Just over two years later, the sequence of JAX® Mice strain C57BL/6J was published.
History of Highseas
Online exclusive article
A history of The Jackson Laboratory's Highseas Conference Center, originally built in 1912 by Professor Rudolph E. Brunnow, a professor at Princeton University.
