JAX® NOTES issue 516, Winter 2010
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In this issue...
Prize4Life and JAX Team up to Fight ALS
Today, there is no cure or significant treatment for amyotrophic lateral sclerosis (ALS, or Lou Gehrig's disease), but that may change in the very near future.
Chemical Treatment Slows ALS in SOD1 Mouse
A recent study involving the SOD1 mouse may lead to a new therapy for ALS patients.
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Six New mES Cell Lines Available
JAX® Services is now offering six new mouse embryonic stem (mES) cell lines.
JAX—West Helps Search for Compounds That Radically Extend Lifespan
In a novel approach to fighting disease and improving human health, RosScreening Inc., a subsidiary of Rostock Group, has enlisted the help of The Jackson Laboratory—West to launch a mouse screening project that will test the ability of some 1,000 compounds to extend the lifespan of mice by at least 30%.
JAX Scientist Investigating Telomere Role in Cancer
Cancer is responsible for approximately 25% of all deaths in the United States since 1950, second only to deaths caused by heart disease. The number of people expected to die of cancer worldwide will reach 9 million in 2015 and 11.4 million in 2030 (World Health Organization).
JAX Resources for Cancer Research
Founded in 1929 as a cancer research facility, The Jackson Laboratory has been an NCI-designated Cancer Center since 1983.
JAX Scientist Awarded Cancer Grant
The American Cancer Society has awarded a $720,000 Research Scholar Grant to JAX Assistant Professor Dr. Kyuson Yun to investigate whether a highly expressed protein in aggressive cancers (including breast, colon, and pancreatic cancers) is also expressed in glioblastoma stem cells.
JAX Patents Unique Genetic Stability Program
Will your mouse-based research stand the test of time? Or will it be confounded by genetic drift, ". . . the constant tendency of genes to evolve even in the absence of selective forces . . . fueled by spontaneous neutral mutations that disappear or become fixed in a population at random" (Silver 1995)?
The NSG, a Better Model for Malaria Research
Each year, 300 to 500 million cases of malaria are reported, and more than a million people die from the disease.
"Drug-less" Diabetes/Obesity Vaccine Tested in JAX® Mice
A preclinical-stage vaccine company named Braasch Biotech LLC recently announced that it has developed a "drug-less" vaccine that may one day be used to treat diabetes, heart disease, Rett syndrome, and other metabolic disorders.
Newly Available JAX Mice Strains
Newly Available JAX® Mice Strains
