New Version of MGI Database Enhances Information on Mouse Models of Human Diseases
JAX® NOTES Issue 500, Winter 2006
Mouse Genome Informatics (MGI) is pleased to announce the release of a new version of its database. Version 3.3 improves your ability to explore phenotypes, sequence, expression, orthology and other related data by integrating data from MGI on mouse genes and strains with data from Online Mendelian Inheritance in Man (OMIM) on mouse models of human disease and human disease etiology.
You can now use MGI to search for either existing and potential mouse models of a human disease or all the human diseases that a mouse can be used to model. You can perform such a search with any of the four MGI query forms (listed below) in the Phenotype/Disease field.
For example, to search for all the mouse models of diabetes that also exhibit insulin resistance, enter "diabetes" and "insulin resistance." The search yields 36 alleles in 25 genes. You can also perform the search by entering "125853" (the OMIM accession ID for Noninsulin-Dependent Diabetes Mellitus, NIDDM) and "insulin resistance." That search yields nine alleles in nine genes. If MGI has data associating a disease with a mouse model, it appears in the browser and query results.
Please send questions and comments to mgi-help@informatics.jax.org.
Four MGI Query Forms
