Both cryopreserved and live Repository strains can be quickly and efficiently expanded to deliver cohorts directly into your discovery program. With JAX® Dedicated Supply Service and JAX® Speed Expansion Service you'll get the mice you need when you need them — fast.
| Stock Number |
Strain Name Strain Description |
Standard Supply |
| 002692 | B6.129S1-Il12atm1Jm/J | Repository- Live |
| Mice homozygous for the Il12atm1Jm targeted mutation on a normally resistant 129/Sv genetic background are unable to restrict the progression of Leishmania major infection, demonstrating the importance of this cytokine for developing such resistance. Homozygotes are unable to mount a delayed-type hypersensitivity (DTH) reaction but a TH2 response is induced. Also known as p35. Please refer to the Il12b-deficient related targeted mutations (Stock No. 002693 and 002694).
In an attempt to offer alleles on well-characterized or multiple genetic backgrounds, alleles are frequently moved to a genetic background different from that on which an allele was first characterized. This is the case for the strain above. It should be noted that the phenotype could vary from that originally described. We will modify the strain description if necessary a ..... | ||
| 002691 | C.129S1(B6)-Il12atm1Jm/J | Cryopreserved - Ready for recovery |
| Mice homozygous for the Il12atm1Jm targeted mutation on a normally resistant 129/Sv genetic background are unable to restrict the progression of Leishmania major infection, demonstrating the importance of this cytokine for developing such resistance. Homozygotes are unable to mount a delayed-type hypersensitivity (DTH) reaction but a TH2 response is induced. Also known as p35. Please refer to the Il12b-deficient related targeted mutations (002693 & 002694). In an attempt to offer alleles on well-characterized or multiple genetic backgrounds, alleles are frequently moved to a genetic background different from that on which an allele was first characterized. This is the case for the strain above. It should be noted that the phenotype could vary from that originally described. We will modify the strain description if necessary as published results become available. | ||
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