Search Criteria: Strain Type is "Insertion"
| Stock Number |
Strain Name Phenotype |
Standard Supply |
| 002027 | 129S8/SvEv-Gpi1c Hprt1b-m2/J | Repository-Cryopreserved |
| 005383 | B6.129S6-Dp(16Cbr1-ORF9)1Rhr/J | Repository-Cryopreserved |
| These mice are trisomic for the mouse chromosome segment orthologus to the human chromosome 21 Down syndrome critical region (DSCR). The borders of the 3.9 Mb region are defined by the carbonyl reductase 1 gene and a site adjacent to the myxovirus (influenza virus) resistance 2 locus. Trisomic mice are viable, fertile and are significantly larger than euploid littermates. Mandible size is enlarged as is skull size, with an overall elongation of the rostrocaudal aspect in comparison to euploid littermates. This mouse may be useful in studies exploring the consequences of polyploidy involving the DSCR. | ||
| 001914 | B6.Cg-Is(HSR;1)1Lub/J | Repository-Cryopreserved |
| 002460 | C3H/HeJ-Oca2p-J Is(7;1)40H/J | Repository-Cryopreserved |
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