Search Criteria: Strain Type is "Robertsonian"

New Strains Under Development

JAX® Mice Strains

Stock
Number
Strain Name
 
Strain Description
Standard Supply
000726 RBF/DnJ
Level 4
The RBF inbred strain arose from crosses with wild mice, originally known as "tobacco mouse", captured in Valle di Poschiavo in S.E. Switzerland. The wild mice originally known as 'tobacco mouse' because of the coat colour. The strain was transferred to Dr. M. Davisson (Dn) in 1981 and subsequently to the production colony of The Jackson Laborotory (J). Mice are homozygous for Robertsonian translocation Rb(1.3)1Bnr, Rb(8.12)5Bnr and Rb(9.14)6Bnr. This strain is useful for production of antibody producing hybridomas.
001802 CByJ.RBF-Rb(8.12)5Bnr/J
Repository- Live
Hybridomas are produced by fusing mouse meloma cells that are deficient in adenosine phosphoribosyltransferase (APRT) with spleen cells from mice immunized with specific antigens. A selection system using AAT (adenosine, aminopterin, and thymidine) medium eliminates all but the fusion cells that are APRT+ . Successful hybridomas must also retain the Igh heavy chain locus on chromosome 12 and one of the Igh light chain loci. The Robertsonian chromosome Rb(8.12)5Bnr can be used to produce hybridomas at a high frequency. Selecting for the Aprt locus on chromosome 8 also selects for the Igh locus on chromosome 12 because the two loci are "genetically linked" by the Robertsonian fusion chromosome. This chromosomal aberration congenic was created by backcrossing the Robertsonian chromosome Rb(8.12)5Bnr on the BALB/cByJ genetic background by Dr. Muriel Davisson at The Jackson Laboratory.
005354 RB156Bnr/Ei rul-Gulosfx-2J/J
Repository- Live
The phenotype of the sfx2J remutation is identifiable at 4-5 weeks of age when the mutants appear smaller than their control littermates and begin to hobble about their cage. Between 5 and 8 weeks of age the mutants develop rear limb paralysis and many die by 8 weeks of age. The phenotypic characteristics of this mutation are similar to the original mutation spontaneous fracture (Gulosfx ) except for the eye phenotype described below that is inherent in the background strain on which the sfx2J mutation arose. Mice homozygous for the sfx2J remutation also had cataracts and rosettes and wavy outer nuclear layer of retinas. The eyes of a female mutant were checked using an opthalmascope and it was found to have cataracts on both eyes (as the strain background has characteristically). It has not yet been determined if the rosettes and wavy outer nuclear layer of the retinas is also characteristic of the background s .....
For more information please see the full phenotype on the strain data sheet
000874 RBA/DnJ
Repository- Live
000729 STOCK Rb(11.13)4Bnr/J
Repository- Live
000929 TIRANO/EiJ
Repository- Live
This wild-derived inbred strain is homozygous for 8 Robertsonian translocations: Rb(1.3)1Bnr, Rb(4.6)2Bnr, Rb(5.15)3Bnr, Rb(11.13)4Bnr, Rb(9.14)6Bnr, Rb(16.17)7Bnr, Rb(2.8)2Lub and Rb(10.12)5Lub (abbreviated Rb1Bnr - Rb7Bnr, Rb2Lub and Rb5Lub, respectively)(LL Washburn, pers. comm.).
001392 ZALENDE/EiJ
Repository- Live
This wild-derived inbred strain is homozygous for 7 Robertsonian translocations: Rb(1.3)1Bnr, Rb(4.6)2Bnr, Rb(5.15)3Bnr, Rb(11.13)4Bnr, Rb(8.12)5Bnr, Rb(9.14)6Bnr, and Rb(16.17)7Bnr (abbreviated Rb1Bnr - Rb7Bnr, respectively)(LL Washburn, pers. comm.).
001099 AEJ/GnRk-Rb(11.14)1Dn/J
Repository-Cryopreserved
002545 B6 x RBA/DnJ
Repository-Cryopreserved
000610 B6 x STOCK Rb(6.15)1Ald/J
Repository-Cryopreserved
000861 B6.Cg-Rb(1.3)1Lub/J
Repository-Cryopreserved
000952 B6.Cg-Rb(10.11)8Bnr/J
Repository-Cryopreserved
000960 B6.Cg-Rb(2.8)2Lub/J
Repository-Cryopreserved
001733 B6.WMP-Rb(10.17)9Mpl/J
Repository-Cryopreserved
001734 B6.WMP-Rb(13.15)10Mpl/J
Repository-Cryopreserved
001727 B6.WMP-Rb(2.16)3Mpl/J
Repository-Cryopreserved
001728 B6.WMP-Rb(3.12)4Mpl/J
Repository-Cryopreserved
001729 B6.WMP-Rb(4.6)5Mpl/J
Repository-Cryopreserved
001732 B6.WMP-Rb(8.9)8Mpl/J
Repository-Cryopreserved
001796 B6Ei.Cg-Rb(1.2)18Lub/J
Repository-Cryopreserved
001921 B6Ei.Cg-Rb(1.7)1Rma/J
Repository-Cryopreserved
001386 B6Ei.Cg-Rb(10.12)5Lub/J
Repository-Cryopreserved
001617 B6Ei.Cg-Rb(10.15)23Lub/J
Repository-Cryopreserved
001795 B6Ei.Cg-Rb(11.13)4Bnr/J
Repository-Cryopreserved
000150 B6Ei.Cg-Rb(11.16)2H/J
Repository-Cryopreserved
000906 B6Ei.Cg-Rb(16.17)8Lub-tw3Lub/+ +/J
Repository-Cryopreserved
001387 B6Ei.Cg-Rb(2.17)11Rma/J
Repository-Cryopreserved
001613 B6Ei.Cg-Rb(5.14)21Lub/J
Repository-Cryopreserved
001616 B6Ei.Cg-Rb(5.15)4Lub/J
Repository-Cryopreserved
001791 B6Ei.Cg-Rb(5.19)1Wh/J
Repository-Cryopreserved
000762 B6Ei.Cg-Rb(6.15)1Ald/J
Repository-Cryopreserved
001798 B6Ei.Cg-Rb(6.16)24Lub/J
Repository-Cryopreserved
001389 B6Ei.Cg-Rb(6.7)13Rma/J
Repository-Cryopreserved
001615 B6Ei.Cg-Rb(7.18)9Lub/J
Repository-Cryopreserved
001797 B6Ei.Cg-Rb(8.12)22Lub/J
Repository-Cryopreserved
000888 B6Ei.Cg-Rb(8.14)16Rma/J
Repository-Cryopreserved
001792 B6Ei.Cg-Rb(9.19)163H/J
Repository-Cryopreserved
001794 B6Ei.WMP-Rb(13.16)1Mpl/J
Repository-Cryopreserved
002470 B6EiC3Sn x B6-Rb(5.8)3Dn/J
Repository-Cryopreserved
004850 B6EiC3Sn-Rb(12.T171665Dn)2Cje/CjeDn
Repository-Cryopreserved
Like B6EiC3Sn a/A - Ts(1716)65Dn (Stock No. 001924), this strain has three copies of most of the genes on mouse Chromosome 16 that are homologues of human Chromosome 21 genes. Transmission of the chromosome 16 segmental trisomy through the female germline is significantly improved over Ts65Dn (43% versus 24%). Dendritic spines on granule cells in the fascia dentata are enlarged in size and decreased in density (Villar AJ, et al. 2005). Unlike Ts65Dn, males are fertile. Mice are 20% smaller in size than controls. This strain serves a model for Down syndrome.
000975 C57BL/6J x STOCK Rb(1.3)1Ei/J
Repository-Cryopreserved
001391 C57BL/6J-Rb(4.15)1Rk/J
Repository-Cryopreserved
001390 C57BL/6J-Rb(6.18)2Dn/J
Repository-Cryopreserved
001793 C57BL/6JEi-Rb(X.2)2Ad/J
Repository-Cryopreserved
000714 CByJ.RBF-Rb(8.12)5Bnr
Repository-Cryopreserved
002040 RB126Bnr/EiJ
Repository-Cryopreserved
002041 RB16Bnr/EiJ
Repository-Cryopreserved
000609 RBB/DnJ
Repository-Cryopreserved
000889 RBC/DnJ
Repository-Cryopreserved
001000 RBD/DnJ
Repository-Cryopreserved
000807 RBJ/DnJ
Repository-Cryopreserved
000862 STOCK Rb(1.7)1Rma/J
Repository-Cryopreserved
000891 STOCK Rb(10.11)5Rma/J
Repository-Cryopreserved
000614 STOCK Rb(10.11)8Bnr/J
Repository-Cryopreserved
000892 STOCK Rb(10.12)5Lub/J
Repository-Cryopreserved
000895 STOCK Rb(11.13)6Lub/J
Repository-Cryopreserved
001100 STOCK Rb(13.16)1Mpl/J
Repository-Cryopreserved
000615 STOCK Rb(16.17)7Bnr
Repository-Cryopreserved
Please see Rb(16.17)7Bnr at the Cytogenetics Models Resource for more information on this strain.
003304 STOCK Rb(16.17)7Bnr-Myo15sh2-2J/J
Repository-Cryopreserved
000898 STOCK Rb(16.17)8Lub/J
Repository-Cryopreserved
000865 STOCK Rb(2.17)11Rma/J
Repository-Cryopreserved
000896 STOCK Rb(2.18)6Rma Rb(12.14)8Rma/J
Repository-Cryopreserved
000867 STOCK Rb(2.18)6Rma/J
Repository-Cryopreserved
000864 STOCK Rb(2.8)2Lub Rb(7.18)9Lub/J
Repository-Cryopreserved
000871 STOCK Rb(3.15)2Rk/J
Repository-Cryopreserved
000980 STOCK Rb(3.8)2Ei/J
Repository-Cryopreserved
000869 STOCK Rb(3.8)2Rma/J
Repository-Cryopreserved
000870 STOCK Rb(3.9)12Lub/J
Repository-Cryopreserved
000873 STOCK Rb(4.11)12Rma/J
Repository-Cryopreserved
000876 STOCK Rb(4.15)4Rma/J
Repository-Cryopreserved
000720 STOCK Rb(4.6)2Bnr/J
Repository-Cryopreserved
000878 STOCK Rb(5.14)21Lub/J
Repository-Cryopreserved
000880 STOCK Rb(5.15)15Rma/J
Repository-Cryopreserved
000881 STOCK Rb(5.17)7Rma/J
Repository-Cryopreserved
000882 STOCK Rb(5.19)1Wh/J
Repository-Cryopreserved
001884 STOCK Rb(5.6)1Ty/J
Repository-Cryopreserved
000885 STOCK Rb(6.16)24Lub
Repository-Cryopreserved
Please see Rb(6.16)24Lub at the Cytogenetics Models Resource for more information on this strain.
000887 STOCK Rb(8.12)22Lub/J
Repository-Cryopreserved
001746 WMP/PasDnJ
Repository-Cryopreserved

(79 stocks)         Back to Top

New Strains Under Development

(See informational text following listing of strains)
How to Register Interest
Please indicate your interest in purchasing any of the strains listed below when they become available for distribution by checking the box next to the strain(s) of interest and then selecting the "Continue" button which leads to an Interest Form.

View a Data sheet for New Strains Under Development
Select the strain name to link to the strain data sheet.

Stock
Number
Strain Name
 
Strain Description
Standard Supply
000613STOCK Rb(9.19)163H/J
On Hold
001887(STOCK Rb(6.16)24Lub x STOCK Rb(16.17)7Bnr)F1/J
Under Development for Cryo

(2 stocks)         Back to Top

New Strains Under Development The Jackson Laboratory serves as a worldwide distributor and national repository for common and rare strains of inbred mice and mice carrying spontaneous mutations or induced mutations (i.e., transgenic, targeted/"knockout", or chemically induced mutations). At any one time, we have over 100 strains at various stages of development and colony expansion. Strains "Under Development" fall into two categories depending on the anticipated demand from the scientific community.
  1. Strains that will be made available from a live distribution colony at The Jackson Laboratory.
    These strains are designated as: "Under Development for Distribution Colony"
  2. Strains that will be made available through the Cryopreservation Repository.
    These strains are designated as: "Under Development for Cryopreservation Repository"
It is VERY IMPORTANT that you register interest in strains Under Development. The anticipated demand for a strain enables us to determine effectively the distribution plan for each strain Under Development. Registering interest also provides benefits to you (including advance notification of pending availability). Whether a strain is made available from a live colony OR from our cryopreservation repository, you may want to consider the option of Dedicated Supply. To learn more about Dedicated Supply, go to Services.

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