Search Criteria: Strain Type is "Robertsonian"

New Strains Awaiting Transfer
Additional Register Interest Strains

JAX® Mice Strains

Stock
Number
Strain Name
 
Strain Description
Standard Supply
004850 B6EiC3Sn-Rb(12.Ts171665Dn)2Cje/CjeDnJ
Repository- Live
The trisomic segment in the Rb(12.Ts171665Dn)2Cje strain is genetically identical to the Ts65Dn strains, Stock No. 001924 and Stock No. 005252, with trisomy of the Chr 16 genes, from Mrpl39 to the distal telomere. Quantitative PCR confirmed the triplication of Chr 16 genes from App to Mx1. Transmission of the chromosome 16 segmental trisomy through the female germline is significantly improved over Ts65Dn (43% versus 24%). Dendritic spines on granule cells in the fascia dentata are enlarged in size and decreased in density (Villar AJ, et al. 2005). Unlike Ts65Dn, males are fertile. Trisomic mice are 20% smaller in size than controls. This strain serves a model for Down syndrome.
001802 CByJ.RBF-Rb(8.12)5Bnr/J
Repository- Live
Hybridomas are produced by fusing mouse meloma cells that are deficient in adenosine phosphoribosyltransferase (APRT) with spleen cells from mice immunized with specific antigens. A selection system using AAT (adenosine, aminopterin, and thymidine) medium eliminates all but the fusion cells that are APRT+ . Successful hybridomas must also retain the Igh heavy chain locus on chromosome 12 and one of the Igh light chain loci. The Robertsonian chromosome Rb(8.12)5Bnr can be used to produce hybridomas at a high frequency. Selecting for the Aprt locus on chromosome 8 also selects for the Igh locus on chromosome 12 because the two loci are "genetically linked" by the Robertsonian fusion chromosome. This chromosomal aberration congenic was created by backcrossing the Robertsonian chromosome Rb(8.12)5Bnr on the BALB/cByJ genetic background by Dr. Muriel Davisson at The Jackson Laboratory.
000726 RBF/DnJ
Repository- Live
The RBF inbred strain arose from crosses with wild mice, originally known as "tobacco mouse", captured in Valle di Poschiavo in S.E. Switzerland. The wild mice originally known as 'tobacco mouse' because of the coat colour. The strain was transferred to Dr. M. Davisson (Dn) in 1981 and subsequently to the production colony of The Jackson Laborotory (J). Mice are homozygous for Robertsonian translocation Rb(1.3)1Bnr, Rb(8.12)5Bnr and Rb(9.14)6Bnr.
001392 ZALENDE/EiJ
Repository- Live
This wild-derived inbred strain is homozygous for 7 Robertsonian translocations: Rb(1.3)1Bnr, Rb(4.6)2Bnr, Rb(5.15)3Bnr, Rb(11.13)4Bnr, Rb(8.12)5Bnr, Rb(9.14)6Bnr, and Rb(16.17)7Bnr (abbreviated Rb1Bnr - Rb7Bnr, respectively)(LL Washburn, pers. comm.).
001099 AEJ/GnRk-Rb(11.14)1Dn/J
Cryopreserved - Ready for recovery
002545 B6 x RBA/DnJ
Cryopreserved - Ready for recovery
000610 B6 x STOCK Rb(6.15)1Ald/J
Cryopreserved - Ready for recovery
014110 B6.Cg-Rb(1.3)1EiJ/AmonJ
Cryopreserved - Ready for recovery
Robertsonian chromosomes are bi-armed (metacentric) chromosomes formed by the joining of two single-armed (acrocentric) chromosomes at the centromere ends. Rb(1.3)1Ei carries a Robertsonian chromosome composed of chromosomes 1 and 3.

Karyotyping of this strain will be the responsibility of the Purchaser.

000861 B6.Cg-Rb(1.3)1Lub/J
Cryopreserved - Ready for recovery
000952 B6.Cg-Rb(10.11)8Bnr/J
Cryopreserved - Ready for recovery
014115 B6.Cg-Rb(10.12)5Lub/JAmonJ
Cryopreserved - Ready for recovery
Robertsonian chromosomes are bi-armed (metacentric) chromosomes formed by the joining of two single-armed (acrocentric) chromosomes at the centromere ends. This strain carries a Robertsonian chromosome composed of chromosomes 10 and 12.

Karyotyping of this strain will be the responsibility of the Purchaser.

000960 B6.Cg-Rb(2.8)2Lub/J
Cryopreserved - Ready for recovery
014113 B6.Cg-Rb(5.19)1Wh/JAmonJ
Cryopreserved - Ready for recovery
Robertsonian chromosomes are bi-armed (metacentric) chromosomes formed by the joining of two single-armed (acrocentric) chromosomes at the centromere ends. This strain carries a Robertsonian chromosome composed of chromosomes 5 and 19.

Karyotyping of this strain will be the responsibility of the Purchaser.

001733 B6.WMP-Rb(10.17)9Mpl/J
Cryopreserved - Ready for recovery
001734 B6.WMP-Rb(13.15)10Mpl/J
Cryopreserved - Ready for recovery
001727 B6.WMP-Rb(2.16)3Mpl/J
Cryopreserved - Ready for recovery
001728 B6.WMP-Rb(3.12)4Mpl/J
Cryopreserved - Ready for recovery
014111 B6.WMP-Rb(3.12)4Mpl/JAmonJ
Cryopreserved - Ready for recovery
Robertsonian chromosomes are bi-armed (metacentric) chromosomes formed by the joining of two single-armed (acrocentric) chromosomes at the centromere ends. Rb(3.12)4Mpl carries a Robertsonian chromosome composed of chromosomes 3 and 12.

Karyotyping of this strain will be the responsibility of the Purchaser.

001729 B6.WMP-Rb(4.6)5Mpl/J
Cryopreserved - Ready for recovery
001732 B6.WMP-Rb(8.9)8Mpl/J
Cryopreserved - Ready for recovery
001796 B6Ei.Cg-Rb(1.2)18Lub/J
Cryopreserved - Ready for recovery
001921 B6Ei.Cg-Rb(1.7)1Rma/J
Cryopreserved - Ready for recovery
001386 B6Ei.Cg-Rb(10.12)5Lub/J
Cryopreserved - Ready for recovery
001617 B6Ei.Cg-Rb(10.15)23Lub/J
Cryopreserved - Ready for recovery
001795 B6Ei.Cg-Rb(11.13)4Bnr/J
Cryopreserved - Ready for recovery
000150 B6Ei.Cg-Rb(11.16)2H/J
Cryopreserved - Ready for recovery
000906 B6Ei.Cg-Rb(16.17)8Lub tw3Lub/+ +/J
Cryopreserved - Ready for recovery
001387 B6Ei.Cg-Rb(2.17)11Rma/J
Cryopreserved - Ready for recovery
001613 B6Ei.Cg-Rb(5.14)21Lub/J
Cryopreserved - Ready for recovery
001616 B6Ei.Cg-Rb(5.15)4Lub/J
Cryopreserved - Ready for recovery
001791 B6Ei.Cg-Rb(5.19)1Wh/J
Cryopreserved - Ready for recovery
000762 B6Ei.Cg-Rb(6.15)1Ald/J
Cryopreserved - Ready for recovery
001798 B6Ei.Cg-Rb(6.16)24Lub/J
Cryopreserved - Ready for recovery
001389 B6Ei.Cg-Rb(6.7)13Rma/J
Cryopreserved - Ready for recovery
001615 B6Ei.Cg-Rb(7.18)9Lub/J
Cryopreserved - Ready for recovery
001797 B6Ei.Cg-Rb(8.12)22Lub/J
Cryopreserved - Ready for recovery
000888 B6Ei.Cg-Rb(8.14)16Rma/J
Cryopreserved - Ready for recovery
001792 B6Ei.Cg-Rb(9.19)163H/J
Cryopreserved - Ready for recovery
001794 B6Ei.WMP-Rb(13.16)1Mpl/J
Cryopreserved - Ready for recovery
002470 B6EiC3Sn x B6-Rb(5.8)3Dn/J
Cryopreserved - Ready for recovery
000975 C57BL/6J x STOCK Rb(1.3)1Ei/J
Cryopreserved - Ready for recovery
Robertsonian chromosomes are bi-armed (metacentric) chromosomes formed by the joining of two single-armed (acrocentric) chromosomes at the centromere ends. Rb(1.3)1Ei is a Robertsonian chromosome composed of Chromosomes 1 and 3.
001391 C57BL/6J-Rb(4.15)1Rk/J
Cryopreserved - Ready for recovery
001390 C57BL/6J-Rb(6.18)2Dn/J
Cryopreserved - Ready for recovery
001793 C57BL/6JEi-Rb(X.2)2Ad/J
Cryopreserved - Ready for recovery
000714 CByJ.RBF-Rb(8.12)5Bnr
Cryopreserved - Ready for recovery
002040 RB126Bnr/EiJ
Cryopreserved - Ready for recovery
002041 RB16Bnr/EiJ
Cryopreserved - Ready for recovery
000609 RBB/DnJ
Cryopreserved - Ready for recovery
000889 RBC/DnJ
Cryopreserved - Ready for recovery
001000 RBD/DnJ
Cryopreserved - Ready for recovery
000807 RBJ/DnJ
Cryopreserved - Ready for recovery
000862 STOCK Rb(1.7)1Rma/J
Cryopreserved - Ready for recovery
000891 STOCK Rb(10.11)5Rma/J
Cryopreserved - Ready for recovery
000614 STOCK Rb(10.11)8Bnr/J
Cryopreserved - Ready for recovery
000892 STOCK Rb(10.12)5Lub/J
Cryopreserved - Ready for recovery
000895 STOCK Rb(11.13)6Lub/J
Cryopreserved - Ready for recovery
001100 STOCK Rb(13.16)1Mpl/J
Cryopreserved - Ready for recovery
000615 STOCK Rb(16.17)7Bnr
Cryopreserved - Ready for recovery
Rb(16.17)7Bnr carries a Robertsonian chromosome containing mouse chromosomes 16 and 17. These mice can be used to generate embryos trisomic for all of mouse Chr 16 by mating to Rb(6.16)24Bnr (Stock No. 000885) to produce (Rb(6.16)24Lub x Rb(16.17)7Bnr)F1 hybrid mice. The F1 hybrid mice are typically mated to C57BL/6J (Stock No. 000664) mice to produce the aneuploid embryos.

Please see the Down Syndrome and Cytogenetics Models Resource for information on other chromosomal aberration strains.
003304 STOCK Rb(16.17)7Bnr-Myo15sh2-2J/J
Cryopreserved - Ready for recovery
000898 STOCK Rb(16.17)8Lub/J
Cryopreserved - Ready for recovery
000865 STOCK Rb(2.17)11Rma/J
Cryopreserved - Ready for recovery
000896 STOCK Rb(2.18)6Rma Rb(12.14)8Rma/J
Cryopreserved - Ready for recovery
000867 STOCK Rb(2.18)6Rma/J
Cryopreserved - Ready for recovery
000864 STOCK Rb(2.8)2Lub Rb(7.18)9Lub/J
Cryopreserved - Ready for recovery
000871 STOCK Rb(3.15)2Rk/J
Cryopreserved - Ready for recovery
000980 STOCK Rb(3.8)2Ei/J
Cryopreserved - Ready for recovery
000869 STOCK Rb(3.8)2Rma/J
Cryopreserved - Ready for recovery
000870 STOCK Rb(3.9)12Lub/J
Cryopreserved - Ready for recovery
000873 STOCK Rb(4.11)12Rma/J
Cryopreserved - Ready for recovery
000876 STOCK Rb(4.15)4Rma/J
Cryopreserved - Ready for recovery
000720 STOCK Rb(4.6)2Bnr/J
Cryopreserved - Ready for recovery
000878 STOCK Rb(5.14)21Lub/J
Cryopreserved - Ready for recovery
000880 STOCK Rb(5.15)15Rma/J
Cryopreserved - Ready for recovery
000881 STOCK Rb(5.17)7Rma/J
Cryopreserved - Ready for recovery
000882 STOCK Rb(5.19)1Wh/J
Cryopreserved - Ready for recovery
001884 STOCK Rb(5.6)1Ty/J
Cryopreserved - Ready for recovery
000885 STOCK Rb(6.16)24Lub
Cryopreserved - Ready for recovery
Rb(6.16)24Bnr carries a Robertsonian chromosome containing mouse chromosomes 6 and 16. These mice can be used to generate embryos trisomic for all of mouse Chr 16 by mating to Rb(16.17)7Bnr (Stock No. 000615) to produce (Rb(6.16)24Lub x Rb(16.17)7Bnr)F1 hybrid mice. The F1 hybrid mice are typically mated to C57BL/6J (Stock No. 000664) mice to produce the aneuploid embryos.

Please see the Down Syndrome and Cytogenetics Models Resource for information on other chromosomal aberration strains.
000887 STOCK Rb(8.12)22Lub/J
Cryopreserved - Ready for recovery
000929 TIRANO/EiJ
Cryopreserved - Ready for recovery
This wild-derived inbred strain is homozygous for 8 Robertsonian translocations: Rb(1.3)1Bnr, Rb(4.6)2Bnr, Rb(5.15)3Bnr, Rb(11.13)4Bnr, Rb(9.14)6Bnr, Rb(16.17)7Bnr, Rb(2.8)2Lub and Rb(10.12)5Lub (abbreviated Rb1Bnr - Rb7Bnr, Rb2Lub and Rb5Lub, respectively)(LL Washburn, pers. comm.).
001746 WMP/PasDnJ
Cryopreserved - Ready for recovery
The wild-derived WMP strain was trapped in Monastir, Tunisia by G Lefranc in 1980. With the exception of chromosome 19 and the sex chromosomes, which are the only acrocentric chromosomes, all other chromosomes are involved in metacentric Robertsonian translocations. In addition, WMP carries a heterozygous reciprocal translocation between chromosomes 13 and 17, (T13.17)1Lub. This strain provides indentifiable marker chromosomes for physical gene mapping.

(80 stocks)         Back to Top

New Strains Awaiting Transfer from the Donor

(See informational text following listing of strains)
How to Register Interest
Please indicate your interest in purchasing any of the strains listed below when they become available for distribution by checking the box next to the strain(s) of interest and then selecting the "Continue" button which leads to an Interest Form.

View a Data sheet for New Strains Awaiting Transfer
Select the strain name to link to the strain data sheet.

Stock
Number
Strain Name
 
Strain Description
Standard Supply
014109B6.Cg-Rb(1.2)18Lub/JAmonJ
Awaiting Transfer from the Donor
This strain carries a Robertsonian chromosome composed of chromosomes 1 and 2.
014117B6.Cg-Rb(11.13)4Bnr/JAmonJ
Awaiting Transfer from the Donor
This strain carries a Robertsonian chromosome composed of chromosomes 11 and 13.
014116B6.WMP-Rb(10.17)9Mpl/JAmonJ
Awaiting Transfer from the Donor
This strain carries a Robertsonian chromosome composed of chromosomes 10 and 17.

(3 stocks)         Back to Top

New Strains Awaiting Transfer from the Donor
  • Receive periodic updates on the status of the colony AWAITING TRANSFER
  • Obtain advance notification of strain availability and opportunity to order prior to the strain being published as available
  • Provide input affecting speed and quantity of availability
The Jackson Laboratory serves as a worldwide distributor and national repository for common and rare strains of inbred mice and mice carrying spontaneous mutations or induced mutations (i.e., transgenic, targeted/"knockout", or chemically induced mutations). At any one time, we have over 100 strains at various stages of development and colony expansion.

It is VERY IMPORTANT that you register interest in strains Awaiting Transfer. The anticipated demand for a strain enables us to determine effectively the distribution plan for each strain. Registering interest also provides benefits to you (including advance notification of pending availability). Whether a strain is made available from a live colony OR from our cryopreservation repository, you may want to consider the option of Dedicated Supply. To learn more about Dedicated Supply, go to Services.

Additional Register Interest Strains

Please indicate your interest in purchasing any of the strains listed below when they become available for distribution by checking the box next to the strain(s) of interest and then selecting the "Continue" button which leads to an Interest Form.

View a Data sheet for a Strain
Select the strain name to link to the strain data sheet.

Stock
Number
Strain Name
 
Strain Description
Standard Supply
014119B6.Cg-Rb(16.17)7Bnr/JAmonJ
In Progress
This strain carries a Robertsonian chromosome composed of chromosomes 16 and 17.
014112B6.Cg-Rb(6.16)24Lub/JAmonJ
In Progress
This strain carries a Robertsonian chromosome composed of chromosomes 6 and 16.
014118B6.Cg-Rb(13.16)1Mpl/JAmonJ
Under Development for Cryo
This strain carries a Robertsonian chromosome composed of chromosomes 13 and 16.
005354RB156Bnr/Ei Dsprul Gulosfx-2J/GrsrJ
On Hold
Gulosfx-2J mutants appear smaller than their control littermates and begin to hobble about their cage at 4-5 weeks of age. The eventually develop rear limb paralysis and many die by 8 weeks of age. Homozygotes also had cataracts and rosettes and wavy outer nuclear layer of retinas.
000613STOCK Rb(9.19)163H/J
On Hold

(5 stocks)         Back to Top


It is VERY IMPORTANT that you Register Interest. The anticipated demand for a strain enables us to determine effectively the distribution plan for each strain.

Send questions to our Technical Support team using the Express Technical Support Form.
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