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Virology Research

 
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Virology Research

Allele Symbol
 
Strain Description		 Stock Number Strain Name
   (link to Data Sheet)
Dmdmdx 018018
Awaiting Transfer from the Donor		 B10ScSn.Cg-Prkdcscid Dmdmdx/J
MDX/SCID mice exhibit necrosis, centrally located nuclei and and the muscle degeneration characteristic of DMD and may be used a dystrophic model for the transplantation of human donor cells to evaluate skeletal muscle regeneration.
H2-Ab1tm1Doi 004606
On Hold		 NOD.Cg-Prkdcscid H2-Ab1tm1Doi Tg(HLA-DQA1,HLA-DQB1)1Dv/SzJ
This strain which is MHC II deficient and has no functional T or B cells expresses a humanized transgenic HLA-DQ8 molecule that has been linked to IDDM development. This model is a valuable genetic tool for identifying the role of HLA-DQ8 in Type 1 Diabetes.
Prkdcscid 018018
Awaiting Transfer from the Donor		 B10ScSn.Cg-Prkdcscid Dmdmdx/J
MDX/SCID mice exhibit necrosis, centrally located nuclei and and the muscle degeneration characteristic of DMD and may be used a dystrophic model for the transplantation of human donor cells to evaluate skeletal muscle regeneration.
Prkdcscid 017620
Awaiting Transfer from the Donor		 NOD.Cg-Prkdcscid Tg(CAG-DsRed*MST)1Nagy/KupwJ
This compound mutant strain combines the immunodeficiency features of the Prkdcscid mutation and widespread fluorescent cell labeling capabilities of CAG-DsRed on the NOD genetic background. These mice are effective recipients of allogeneic and xenogenic grafts, and are an excellent source of fluorescent-labeled cells for transfer experiments.
Prkdcscid 004606
On Hold		 NOD.Cg-Prkdcscid H2-Ab1tm1Doi Tg(HLA-DQA1,HLA-DQB1)1Dv/SzJ
This strain which is MHC II deficient and has no functional T or B cells expresses a humanized transgenic HLA-DQ8 molecule that has been linked to IDDM development. This model is a valuable genetic tool for identifying the role of HLA-DQ8 in Type 1 Diabetes.
Tg(CAG-DsRed*MST)1Nagy 017620
Awaiting Transfer from the Donor		 NOD.Cg-Prkdcscid Tg(CAG-DsRed*MST)1Nagy/KupwJ
This compound mutant strain combines the immunodeficiency features of the Prkdcscid mutation and widespread fluorescent cell labeling capabilities of CAG-DsRed on the NOD genetic background. These mice are effective recipients of allogeneic and xenogenic grafts, and are an excellent source of fluorescent-labeled cells for transfer experiments.
Tg(HLA-DQA1,HLA-DQB1)1Dv 004606
On Hold		 NOD.Cg-Prkdcscid H2-Ab1tm1Doi Tg(HLA-DQA1,HLA-DQB1)1Dv/SzJ
This strain which is MHC II deficient and has no functional T or B cells expresses a humanized transgenic HLA-DQ8 molecule that has been linked to IDDM development. This model is a valuable genetic tool for identifying the role of HLA-DQ8 in Type 1 Diabetes.
Tg(TcraTcrbVP2)1Bkim 018030
Awaiting Transfer from the Donor		 SJL.Cg-Tg(TcraTcrbVP2)1Bkim/J
This transgenic mouse expressed the TMEV capsid protein peptide, VP274-86, specific regulatory T cell receptor. These mice are useful for studying Th17 responses to viral infection and subsequent inflammatory diseases.

(8 stocks)

 

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