Strains Newly Available

Sensorineural Research


Strains Under Development for all Sensorineural Research models.
View all Research Models for Sensorineural Research
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Allele Symbol Stock Number Strain Name
 
Description		 Standard Supply
Agtpbp1pcd-8J 008292 BALB/cJ-Agtpbp1pcd-8J/J
Repository- Live
Cdh23ahl 007048 DBA/2J-Gpnmb+/SjJ
Repository- Live
This coisogenic strain has a functional allele of Gpnmb. Homozygous mice do not develop the elevated intraocular pressure or glaucoma found in DBA/2J mice (Stock 000671), although they exhibit a mild iris stromal atrophy (ISA). This strain provides a genetically matched control for DBA/2J.
Dscamdel17 008000 B6.CBy-Dscamdel17/RwbJ
Repository- Live
Mice homozygous for this spontaneous mutation become severely uncoordinated by postnatal day 3, developing spontaneous seizures and kyphosis. On the C57BL/6 background, homozygotes exhibit a severe phenotype and die shortly after birth. Retinal amacrine cells display defects in the arborization of processes and spacing of cell bodies. This mutant mouse strain may useful in studies of the retina and the mechanism of neuronal self-avoidance.
Dvl1tm1Awb 007965 129S-Dvl1tm1Awb/J
Repository- Live
Homozygotes exhibit diminished social interaction behavior, do not barber or trim whiskers of cagemates, show subordinance in social dominance tests, do not sleep huddled together and do not build nests. This mutant mouse strain may be useful in studies of social behavior, sensorimotor gating, and possibly psychiatric disorders.
Dvl1tm1Awb 007969 B6.129S6-Dvl1tm1Awb/J
Repository- Live
Mice that are homozygous for this targeted mutation on the 129S genetic background exhibit diminished social interaction behavior, do not barber or trim whiskers of cagemates, show subordinance in social dominance tests, do not sleep huddled together and do not build nests. This mutant mouse strain may be useful in studies of social behavior, sensorimotor gating, and possibly psychiatric disorders.
EgfrVel 006926 C57BL/6J-EgfrVel/J
Repository- Live
Esrrbtm1.1Nat 007674 STOCK Esrrbtm1.1Nat/J
Repository- Live
These Nr3b2CKO mutant mice may be useful in generating conditional mutations to study disorders of hearing and balance, inner ear development (such as endolymph-producing epithelia within the auditory and vestibular divisions), and control of cell fate decisions by nuclear receptors.
Esrrbtm1.2Nat 007674 STOCK Esrrbtm1.1Nat/J
Repository- Live
These Nr3b2CKO mutant mice may be useful in generating conditional mutations to study disorders of hearing and balance, inner ear development (such as endolymph-producing epithelia within the auditory and vestibular divisions), and control of cell fate decisions by nuclear receptors.
Gpi1a-m1J 006562 B6.CBy(Cg)-Gusbmps Gpi1a-m1J/BrkJ
Repository- Live
Gpnmb+ 007048 DBA/2J-Gpnmb+/SjJ
Repository- Live
This coisogenic strain has a functional allele of Gpnmb. Homozygous mice do not develop the elevated intraocular pressure or glaucoma found in DBA/2J mice (Stock 000671), although they exhibit a mild iris stromal atrophy (ISA). This strain provides a genetically matched control for DBA/2J.
Gusbmps 006562 B6.CBy(Cg)-Gusbmps Gpi1a-m1J/BrkJ
Repository- Live
Gusbmps 006564 B6(C)-KitW-41J Gusbmps/BrkJ
Repository-Cryopreserved
Hc0 007048 DBA/2J-Gpnmb+/SjJ
Repository- Live
This coisogenic strain has a functional allele of Gpnmb. Homozygous mice do not develop the elevated intraocular pressure or glaucoma found in DBA/2J mice (Stock 000671), although they exhibit a mild iris stromal atrophy (ISA). This strain provides a genetically matched control for DBA/2J.
KitW-41J 006564 B6(C)-KitW-41J Gusbmps/BrkJ
Repository-Cryopreserved
Lgals1tm1Rob 006337 B6.Cg-Lgals1tm1Rob/J
Repository- Live
Olfr151tm28Mom 006677 STOCK Olfr151tm28Mom/MomJ
Repository- Live
Olfr17tm1Mom 006595 B6;129P2-Olfr17tm1Mom/MomJ
Repository- Live
Oprd1tm1Kff 007557 B6.129S2-Oprd1tm1Kff/J
Repository- Live
Oprk1tm1Kff 007558 B6.129S2-Oprk1tm1Kff/J
Repository- Live
Oprm1tm1Kff 007559 B6.129S2-Oprm1tm1Kff/J
Repository- Live
Rom1tm1Mci 004510 STOCK Rom1tm1Mci/J
Repository- Live
Tmc1dn 006169 CBA.Cg-Tmc1dn/AjgJ
Repository- Live
Homozygotes for this spontaneous mutation exhibit degeneration in the spiral ganglion neurons as well as the organ of Corti and the saccular macula. Mice are deaf throughout life. This strain may be used to research inherited deafness.
Tyrc-2J 007484 B6.Cg-Tyrc-2J Tg(Tyr)3412ARpw Tg(Sry-EGFP)92Ei/EiJ
Repository- Live
Tg(Camk2a-Bdnf)A9Stl 006579 C57BL/6-Tg(Camk2a-Bdnf)A9Stl/J
Repository- Live
Tg(Crx-GFP,-ALPP)1Clc 007066 B6.SJL-Tg(Crx-GFP,-ALPP)1Clc/J
Repository- Live
Tg(Nes-cre)1Kln 007674 STOCK Esrrbtm1.1Nat/J
Repository- Live
These Nr3b2CKO mutant mice may be useful in generating conditional mutations to study disorders of hearing and balance, inner ear development (such as endolymph-producing epithelia within the auditory and vestibular divisions), and control of cell fate decisions by nuclear receptors.
Tg(Sox2-cre)1Amc 007674 STOCK Esrrbtm1.1Nat/J
Repository- Live
These Nr3b2CKO mutant mice may be useful in generating conditional mutations to study disorders of hearing and balance, inner ear development (such as endolymph-producing epithelia within the auditory and vestibular divisions), and control of cell fate decisions by nuclear receptors.
Tg(Sry-EGFP)92Ei 007484 B6.Cg-Tyrc-2J Tg(Tyr)3412ARpw Tg(Sry-EGFP)92Ei/EiJ
Repository- Live
Tg(Tyr)3412ARpw 007484 B6.Cg-Tyrc-2J Tg(Tyr)3412ARpw Tg(Sry-EGFP)92Ei/EiJ
Repository- Live

(29 stocks)

 

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