Search Criteria: Research Area is "Immunology and Inflammation Research: Autoimmunity (lupus erythematosus, control)"
Strains from the Research Colonies of Jackson Laboratory Scientists
| Stock Number |
Strain Name Strain Description |
Standard Supply |
| 000742 | BXSB.B6-Yaa+/J | Repository-Cryopreserved |
| This strain is a control for BXSB/MpJ (stock #000740), which develops spontaneous autoimmune disease characterized by moderate lymph node and spleen enlargement, hemolytic anemia, hypergammaglobulinemia, and immune complex glomerulonephritis. This control congenic strain, lacking the BXSB Y Chromosome and therefore lacking Yaa, does not develop the autoimmune disease. | ||
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IMPORTANT NOTE: Price information is on the strain data sheet which can be viewed by clicking on the strain name.
| Stock Number |
Strain Name Strain Description |
Standard Supply |
| 001925 | BXSB.B6-Yaa+/MobJ | Research Strain |
| This BXSB strain carries the wild-type allele of the Yaa gene from C57BL/6 and serves as a control strain for BXSB/MpJ Yaa (Stock No. 000740). BXSB/MpJ Yaa mice develop spontaneous autoimmune disease characterized by moderate lymph node and spleen enlargement, hemolytic anemia, hypergammaglobulinemia, and immune complex glomerulonephritis. | ||
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