Search Criteria: Research Area is "Research Tools: Cancer Research (Gliomas/Glioblastomas, induced)"

JAX® Mice Strains

Stock
Number
Strain Name
 
Strain Description
Standard Supply
003528 STOCK Tg(GFAP-TVA)5Hev/J
Repository-Cryopreserved
This strain expresses the avian cell surface receptor(TVA) for subgroup A avian leukosis viruses. The transgene is under the control of an astrocyte-specific promoter derived from the human glial fibrillary acidic protein (GFAP ) gene. The result is to render glial cells specifically susceptible to infection by viral vectors making possible the glia-specific viral transfer of genes.
003529 STOCK Tg(NES-TVA)12Hev/J
Repository-Cryopreserved
This strain expresses the avian cell surface receptor(TVA) for subgroup A avian leukosis viruses. The transgene is under the control of a glial progenitor-specific promoter derived from the human nestin (NES) gene. The result is to render glial progenitor cells specifically susceptible to infection by viral vectors making possible the glia-specific viral transfer of genes. Please note: Mice recovered from this cryopreserved colony may have retinal degeneration.

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