Search Criteria: Research Area is "Reproductive Biology Research: Fertility Defects Turner's syndrome"

JAX® Mice Strains

Stock
Number
Strain Name
 
Strain Description
Standard Supply
000314 B6CBACa Aw-J/A-EdaTa/J-XO
Repository- Live
XO or monsomy X mice lack a second sex chromosome. The condition is inherited as an X-linked dominant trait with male lethality. XO mice exhibit some degree of growth retardation, high frequency hearing loss, reduced thyroid activity, reduced body temperature and some behavioral abnormalities. Unlike Turner Syndrome in humans, XO females are fertile. The two-step mating system for this strain (described under Mating System) incorporates the X-linked coat color marker tabby so that mice can be identified by a combination of coat color and sex. This strain may be useful for studies of Turner Syndrome or X-linked recessive alleles.

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