Search Criteria: Research Area is "Neurobiology Research: Receptor Defects (glutamate receptor: NMDA)"

JAX® Mice Strains

Stock
Number
Strain Name
 
Strain Description
Standard Supply
005246 B6.129S4-Grin1tm2Stl/J
Repository- Live
These mice possess loxP sites flanking approximately 12kb of sequence of the targeted gene that encodes the entire transmembrane domain and C-terminal region. Mice that are homozygous for this allele are viable, fertile, normal in size and do not display any gross physical or behavioral abnormalities.

When bred to a strain expressing Cre recombinase in the CA3 region of the hippocampus (see Stock No. 006474 for example), this mutant mouse strain may be useful in studies of associative memory recall.

When bred to a strain expressing Cre recombinase in the CA1 region of the hippocampus (see Stock No. 005359 for example), this mutant mouse strain may be useful in studies of nonspacial memory.

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