Search Criteria: Research Area is "Hematological Research: Anemia, Iron Deficiency and Transport Defects (microcytic) (iron deficiency)"
| Stock Number |
Strain Name Strain Description |
Standard Supply |
| 000023 | FL/1ReJ | Repository-Cryopreserved |
| 000025 | FL/4ReJ | Repository-Cryopreserved |
| 000259 | JE/LeJ | Repository-Cryopreserved |
| Mice homozygous for the jerker spontaneous mutation (Espnje) show behavior typical of the circling mutants - head-tossing, circling, and hyperactivity. Homozygous mutant mice are deaf from birth and have no detectable stimulus-related cochlear potential at any stage. The abnormal behavior and deafness are associated with postnatal degeneration of the sensory cells of the cochlea and the sacculus and utriculus in homozygotes. The primary influence of the jerker gene appears to be on the apical hair cells, not development of neural structures. Heterozygous jerker mice undergo a similar type of degeneration, but the onset is delayed. Auditory brainstem response is totally absent in homozygotes while heterozygous mice undergo a progressive impairment with age. JE/Le mice are also homozygous for the nonagouti (a), flexed tail (f), and ruby-eye (Hps6ru) mutations. | ||
| 000791 | WB.Cg-f/J | Repository-Cryopreserved |
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