Search Criteria: Research Area is "Sensorineural Research: Cataracts (nuclear)"
| Stock Number |
Strain Name Strain Description |
Standard Supply |
| 000385 | 129S;AKR-bs/J | Repository-Cryopreserved |
| Mice homozygous for the spontaneous blind sterile mutation (bs) are characterized by bilateral nuclear cataracts, smaller than normal eyes, and glossy coats. Female mutant mice are fertile but males are sterile. Cataracts are visible in 16 day embryos and continue to adulthood. Adult male mice copulate normally but have smaller than normal testes. Defects in spermatogenesis lead to a reduced number of sperm and those that are formed completely lack acrosomes. | ||
| 004275 | B6.Cg-Fignfi/Frk | Repository-Cryopreserved |
| 002000 | C3.Cg-CrygeElo/J | Repository-Cryopreserved |
| 002352 | STOCK MipCat-Fr/J | Repository-Cryopreserved |
| 001385 | STOCK lop13/J | Repository-Cryopreserved |
| lop13 is a recessive mutation that causes bilateral cataracts that do not affect the cortex of the lens. This presents at 3 to 4 weeks of age as a white area in the center of the lens. The size of the eyes is normal. (Varnum, 1981.) | ||
| 000312 | STOCK stb + a/+ Fignfi a/J | Repository-Cryopreserved |
| Mice homozygous for the fidget spontaneous mutation (Fignfi) toss their heads from side to side and tend to run in circles. Homozygous fidgit mice are hypersensitive to sound in early life, but later lose hearing ability. Corneal lesions are common, and hind foot polydactylism occurs. The bony labyrinth is quite defective. Other abnormalities including small eyes, absence of lachrymal glands, dislocation of the hip, and displaced parafloccular lobes of the cerebellum. Viability of homozygotes is usually less than normal and fertility is poor. The STOCK is also carrying the stubby spontaneous mutation (stb). Homozygous stubby mice are recognizable at 4 or 5 days by a domed head and thick short tail. Adult stubby mice have shorter heads, bodies, and legs compared to wildtype mice. Most females are fertile but males do not breed. Male mice do produce normal numbers of motile sperm. Cartilage histology is within normal limits, but chondrogenesis stops earlier than
..... For more information please see the full descriiption on the strain data sheet | ||
(6 stocks) Back to Top
Send questions to our Technical Support team using the Express Technical Support Form.
(3.2)