Search Criteria: Research Area is "Mouse/Human Gene Homologs: apolipoprotein A1 deficiency, amyloid polyneuropathy-nephropathy"

JAX® Mice Strains

Stock
Number
Strain Name
 
Strain Description
Standard Supply
002055 B6.129P2-Apoa1tm1Unc/J
Repository- Live
Mice homozygous for the Apoa1tm1Unc targeted mutation have no APOA1 protein in their plasma. They have severely reduced levels of plasma cholesterol and HDL-cholesterol after overnight fasting. They also show a deficiency in alpha-migrating HDL particles. The Apoa1tm1Unc mutant mice appear to develop normally.

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