Search Criteria: Research Area is "Mouse/Human Gene Homologs: ataxia telangiectasia"

JAX® Mice Strains

Stock
Number
Strain Name
 
Strain Description
Standard Supply
002753 129S6/SvEvTac-Atmtm1Awb/J
Repository- Live
Mice homozygous for the Atmtm1Awb targeted mutation display many of the characteristics of ataxia telangiectasia, including growth retardation, neurologic dysfunction, infertility, defects in T lymphocyte maturation, and extreme sensitivity to gamma-irradiation. Most homozygotes develop thymic lymphoma between 2 and 4 months of age. Heterozygous mice display no abnormalities through eight months of age.

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