Resource manuals
Resource manuals are available on the following topics:
- Autoimmune disease
- Breeding strategies
- Cancer
- Cardiovascular
- Infectious disease
- Neurobiology
- Research tools
- Sensorineural research
- Type 2 diabetes & obesity
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Autoimmune Disease ResearchThis resource manual highlights the extensive resources available from The Jackson Laboratory to help biomedical researchers with their mouse-based autoimmune disease research. It includes over 70 JAX® Mice models as well as JAX® Services appropriate for autoimmune disease research. |
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Breeding Strategies for Maintaining Mice ColoniesThis manual describes breeding strategies and techniques for maintaining colonies of laboratory mice. These techniques have been developed and used by The Jackson Laboratory for over 75 years. They are safe, reliable, economical, efficient, and ensure that the mouse strains produced are genetically well defined. |
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Cancer ResearchThe purpose of the Cancer Resource Manual is to inform investigators of the extensive resources available for cancer research at The Jackson Laboratory. They include hundreds of cancer research mouse models, publicly accessible databases such as the Mouse Tumor Biology Database, courses and conferences on and related to cancer and stem cell research, and the results of research by Jackson Laboratory scientists. |
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Cardiovascular ResearchThis manual highlights and compares more than 30 JAX® Mice models suitable for cardiovascular research. It also describes other Jackson Laboratory resources, including courses, Web sites, and JAX® Services, as well as briefly summarizing relevant research conducted by Jackson Laboratory Investigators. |
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Infectious Disease ResearchThis manual briefly describes various infectious diseases, summarizes selected studies, and describes JAX® Mice models useful for researching these diseases: HIV (AIDS), anthrax, botulism, ebola, plague, smallpox, and tularemia. |
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Neurobiology ResearchThe Neurobiology Resource Manual summarizes the neuroscience research of Jackson Laboratory scientists, describes Jackson Laboratory courses and web sites related to neuroscience research, and showcases nearly 30 of over 600 JAX® Mice models suitable for neurobiology research. |
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Research ToolsThe development of cutting-edge genetic tools such as Cre-lox, FLP-FRT, and fluorescent proteins has revolutionized the ability of research scientists to manipulate the mouse genome. These relatively new technologies, combined with more traditional tools, including Tet and lacZ expression systems, provide abundant possibilities for developing a new generation of genetically engineered mice to study normal gene function(s), and how alteration of these functions leads to disease. This manual is a guide to understanding the basic mechanisms of these technologies, how “research tool” mouse strains that implement these technologies can be used, and how to find these strains in the JAX® Mice Database. |
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Sensorineural ResearchThis Resource Manual briefly describes the sensorineural research conducted by Jackson Laboratory scientists, over 20 of the hundreds of suitable JAX® Mice, JAX online resources, and Jackson Laboratory courses and conferences relevant to sensorineural research. Request a copy of the sensorineural research resource manual |
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Type 2 Diabetes & Obesity ResearchThis manual describes and compares traditional and newly-developed JAX® Mice models of type 2 diabetes and diet-induced obesity (diabesity), describes the Diet Induced Obesity, Compound Evaluation, and Model Characterization programs offered by JAX® Services, summarizes the research of Jackson Laboratory scientists investigating diabetes and associated diseases, and lists the major diabetes-associated resources available to the biomedical research community. Request a copy of the type 2 diabetes & obesity resource manual |



