Manuals are available on the following topics:
A Field Guide to Working with Mouse Models of Huntington's Disease
Working jointly with CHDI and PsychoGenics, Inc., we now have this valuable resource available for you. Inside the field guide you'll find:
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Working with ALS Mice
Guidelines for preclinical testing and colony management
This informative resource, prepared by scientists with Prize4Life and The Jackson Laboratory, discusses considerations for preclinical studies using SOD1 mice, colony management, QPCR protocol for determining copy number, and provides a sample neurological scoring system and template pedigree ledger.
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Reference Guide to Mouse Models of Spinal Muscular Atrophy
This reference guide summarizes the history of SMA mouse model development. It describes the original models developed in the laboratories of Drs. Michael Sendtner at the University of Worzburg and Arthur Burghes at Ohio State University, the latest models that allow temporal and tissue specific control of SMN expression, and models under development. It includes protocols for maintaining SMA models, criteria for choosing the right model(s), and techniques for maintaining the genetic and phenotypic integrity of future models.
Visit our SMA Resource