Type 1 diabetes resources
Type 1 diabetes, once known as juvenile diabetes, is a disease that results from the body not making sufficient insulin to control blood sugar. Complications of type 1 diabetes include: heart disease (cardiovascular disease), blindness (retinopathy), nerve damage (neuropathy), and kidney damage (nephropathy). The Jackson Laboratory has 49 strains available for studying type 1 diabetes and many others under development.
JAX® Mice for type 1 diabetes research
- All diabetes strains
- Type 1 diabetes (IDDM) strains
- Type 1 diabetes (IDDM) analysis strains
- Research tool strains
Type 1 Diabetes Resource
The National Center for Research Resources (NCRR) at NIH has funded a Type 1 Diabetes Resource at The Jackson Laboratory. The purpose of this resource is to collect and cryopreserve ~ 150 mouse stocks important to research in type 1 diabetes.
STZ-induced diabetes models
C57BL/6J males with streptozotocin (STZ)-induced diabetes shipped at 8-10 days post injection. Protocols can be modified for other strains and sexes.
References
An ongoing, growing list of published research using type 1 diabetes strains.
Type 1 diabetes research at The Jackson Laboratory
See the faculty research page for Dr. David Serreze, Ph.D. and for Dr. Ed Leiter, Ph.D.
Incidence Studies
Incidence studies done by the Type 1 Diabetes Resource
