In Vivo Services for cancer researchers
Located in Sacramento, California, JAX® In Vivo Services deliver target validation and efficacy testing in the context of mouse models of human disease through leveraging our extensive collection of mouse strains. We provide highly customizable preclinical oncology research services to help customers evaluate novel anticancer therapies.
Under the direction of Dr. Neal Goodwin, the JAX® In Vivo Services cancer program offers a breadth of technologies that span from traditional xenograft services to advanced humanized mouse models of cancer.
Technical strengths
- Xenograft, orthotopic, and endogenous mouse model platforms for multiple human cancer therapeutic areas
- State-of-the-art phenotyping laboratory featuring high-throughput, cost-effective, and non-invasive test platforms for characterizing models, evaluating key physiological parameters, validating drug targets, and testing drug efficacy
- Non-invasive bioluminescent and fluorescent imaging
- Flexibility to customize studies and import client-provided animals and cancer cell lines
Why work with The Jackson Laboratory?
- Facilitated access to our best JAX® Mice cancer models including the NOD.Cg-PrkdcscidIl2rgtm1Wjl/SzJ (stock #005557) mouse for developing humanized mouse models of cancer
- Ph.D. study directors and technical staff dedicated specifically for cancer in vivo services
- Highly skilled experts at dosing and testing drug efficacy in over 100 mouse models, including diverse cancer models
- Support from our extensive research staff, which includes over 200 Ph.D.s, M.D.s, and D.V.M.s
