Texas Institute for Genomic Medicine (TIGM) resources
Extensive library of knockout mice and ES cell clones
The Texas Institute for Genomic Medicine (TIGM) is an excellent resource for academic researchers looking to procure genetically engineered knockout mice and mouse embryonic stem (ES) cells quickly and with favorable intellectual property (IP) terms. TIGMs resources include the world's largest gene trap library of ES cells in the C57BL/6 mouse strain and access to the largest library of ES cells in the 129/SvEvBrd mouse strain.
C57BL/6 gene trap library
The TIGM gene trap library contains approximately 350,000 cell lines in the C57BL/6 mouse background. This library contains mutated ES cell clones representing more than 10,000 genes.
129/SvEvBrd gene trap library
TIGM has access to a privately held 129/SvEvBrd gene trap library. This library contains more than 270,000 sequence-tagged embryonic stem cell clones in the 129/SvEvBrd mouse strain representing mutations in over 9,000 genes. The National Institutes of Health (NIH) has obtained rights to a subset of these lines, thus allowing TIGM to make them available for distribution to academic researchers on a subsidized basis.
Together, these established resources provide wide coverage of the mouse genome with over 620,000 cell lines representing over 13,000 unique genes.
Online public database
TIGM has an extensive, user-friendly database accessible via the Internet. It allows you to search through our C57BL/6 or the 129/SvEvBrd gene trap libraries, inquire about a specific line, and place an order. Search by: Entrez Gene ID, Gene symbol, Keyword, Sequence, or Chromosome.
For a detailed price quote for any of these resources, contact TIGM at 888-377-TIGM (toll-free U.S. and Canada), +1-713-677-7429, or email info@tigm.org.
