JAX Mice Database - 000063 B6C3Fe a/a-sy/J

Strain Name:	B6C3Fe a/a-sy/J
Stock Number:	000063
Availability:	Cryopreserved - Ready for recovery

Description
Phenotype
Genes & alleles
Genotyping
Health & husbandry
References
Purchasing information
Terms of Use

Description

The genotypes of the animals provided may not reflect those discussed in the strain description or the mating scheme utilized by The Jackson Laboratory prior to cryopreservation. Please inquire for possible genotypes for this specific strain.

Strain Information

Former Names B6C3Fe-a/a-sy (Changed: 15-DEC-04 )

Type Mutant Strain; Spontaneous Mutation;
Additional information on Genetically Engineered and Mutant Mice.

Visit our online Nomenclature tutorial.

Species laboratory mouse

Generation N15 F1

Description
Most mice homozygous for the shaker-with-syndactylism mutation (sy) die within the first month, and none have lived to breed. Homozygous mutant mice may be syndactylous on all four feet; the forefeet may often be normal and possibly one or both hindfeet very occasionally so. The remainder of the skeleton shows many slight anomalies in addition to small size. The shafts of the long bones are considerably thinner than normal, and there are differences in shape of the sacral vertebrae and the scapula. Abnormal behavior appears during the first week. It consists of head-tossing and some circling, and the affected mice are always deaf. Abnormalities of the labyrinth can be seen at E13.
Development
This shaker-with-syndactylism mutation (sy) was found by Dr. P. Hertwig among descendants of an irradiated male.

Related Strains

Strains carrying a allele

003879 B10;TFLe-a/a T tf/+ tf/J

001538 B6 x B6C3Sn a/A-T(1;9)27H/J

000916 B6 x B6C3Sn a/A-T(5;12)31H/J

000602 B6 x B6C3Sn a/A-T(8;16)17H/J

000618 B6 x FSB/GnEi a/a Ctsl^fs/J

000577 B6 x STOCK a Oca2^p Hps5^ru2 Ednrb^s/J

000601 B6 x STOCK a/a T(7;18)50H/J

000592 B6 x STOCK T(2;4)13H a/J

000001 B6.C3 A/a Mgrn1^md/J

000231 B6;C3Fe a/a-Csf1^op/J

000785 B6;D2-a Es1^e/EiJ

000604 B6C3 a/A-T(10;13)199H +/+ Lyst^bg-J/J or Lyst^bg-2J/J

002807 B6C3Fe a/a-Meox2^fla/J

000224 B6C3Fe a/a-Scyl1^mdf/J

001037 B6C3Fe a/a-Agtpbp1^pcd/J

000221 B6C3Fe a/a-Alx4^lst-J/J

002062 B6C3Fe a/a-Atp7a^Mo-8J/J

001756 B6C3Fe a/a-Cacng2^stg/J

001815 B6C3Fe a/a-Col1a2^oim/J

000209 B6C3Fe a/a-Dh/J

000211 B6C3Fe a/a-Dst^dt-J/J

000210 B6C3Fe a/a-Edar^dl-J/J

000207 B6C3Fe a/a-Edaradd^cr/J

000182 B6C3Fe a/a-Eef1a2^wst/J

001278 B6C3Fe a/a-Glra1^spd/J

000241 B6C3Fe a/a-Glrb^spa/J

002875 B6C3Fe a/a-Hoxd13^spdh/J

000304 B6C3Fe a/a-Krt71^Ca Scn8a^med-J/J

000226 B6C3Fe a/a-Large^myd/J

000636 B6C3Fe a/a-Lmx1a^dr-J/J

001280 B6C3Fe a/a-Lse/J

001573 B6C3Fe a/a-Mitf^Mi/J

001035 B6C3Fe a/a-Napa^hyh/J

000181 B6C3Fe a/a-Otog^twt/J

000278 B6C3Fe a/a-Papss2^bm Hps1^ep Hps6^ru/J

000205 B6C3Fe a/a-Papss2^bm/J

002078 B6C3Fe a/a-Pcdh15^av-2J/J

000246 B6C3Fe a/a-Pitpna^vb/J

001430 B6C3Fe a/a-Ptch1^mes/J

000506 B6C3Fe a/a-Qk^qk/J

000235 B6C3Fe a/a-Reln^rl/J

000237 B6C3Fe a/a-Rora^sg/J

000290 B6C3Fe a/a-Sox10^Dom/J

000230 B6C3Fe a/a-Tcirg1^oc/J

003612 B6C3Fe a/a-Trak1^hyrt/J

001512 B6C3Fe a/a-Ttn^mdm/J

001607 B6C3Fe a/a-Unc5c^rcm/J

000005 B6C3Fe a/a-Wc/J

000243 B6C3Fe a/a-Wnt1^sw/J

000248 B6C3Fe a/a-Xpl/J

001750 B6C3Fe a/a-Xs^J/J

000624 B6C3Fe a/a-anx/J

008044 B6C3Fe a/a-bpck/J

003020 B6C3Fe a/a-dep/J

002018 B6C3Fe a/a-din/J

002339 B6C3Fe a/a-nma/J

000240 B6C3Fe a/a-soc/J

001055 B6C3Fe a/a-tip/J

000245 B6C3Fe a/a-tn/J

000296 B6C3Fe-a/a Hoxa13^Hd Mcoln3^Va-J/J

000019 B6C3Fe-a/a-Itpr1^opt/J

001022 B6C3FeF1/J a/a

006450 B6EiC3 a/A-Vss/GrsrJ

000971 B6EiC3 a/A-Och/J

000551 B6EiC3 a/A-Tbx15^de-H/J

000557 B6EiC3-+ a/Lnp^Ul A/J

000503 B6EiC3Sn a/A-Gy/J

001811 B6EiC3Sn a/A-Otc^spf-ash/J

002343 B6EiC3Sn a/A-Otc^spf/J

000391 B6EiC3Sn a/A-Pax6^Sey-Dey/J

001924 B6EiC3Sn a/A-Ts(17¹⁶)65Dn

001923 B6EiC3Sn a/A-Ts(4¹⁷)2Lws Tim^T(4;17)3Lws/J

000225 C3FeLe.B6 a/a-Ptpn6^me/J

008425 C3FeLe.B6-a Trl/J

000198 C3FeLe.B6-a/J

000291 C3FeLe.Cg-a/a Hm Kitl^Sl Krt71^Ca-J/J

001886 C3HeB/FeJLe a/a-gnd/J

000584 C57BL/6J-+ T(1;2)5Ca/a +/J

000284 CWD/LeJ

000670 DBA/1J

000671 DBA/2J

001057 HPT/LeJ

000260 JGBF/LeJ

000265 MY/HuLeJ

000308 SSL/LeJ

000994 STOCK a Myo5a^d Mreg^dsu/J

000064 STOCK a Tyrp1^b Si^si/J

002238 STOCK a Tyrp1^b shmy/J

001433 STOCK a skt/J

000579 STOCK a tp/J

000319 STOCK a us/J

002648 STOCK a/a Cln6^nclf/J

000317 STOCK a/a Egfr^wa2/J

000302 STOCK a/a Mitf^Mi-wh +/+ Itpr1^opt/J

000286 STOCK a/a Myo5a^d fd/+ +/J

000206 STOCK a/a Tyr^c-h/J

001432 STOCK a/a Tyrp1^b sks/Tyrp1^b +/J

000281 STOCK a/a ma Flg^ft/ma Flg^ft/J

000312 STOCK stb + a/+ Fign^fi a/J

000596 STOCK T(2;11)30H/+ x AEJ-a Gdf5^bp-H/J or A/J-a Gdf5^bp-J/J

000970 STOCK T(2;16)28H A/T(2;16)28H a/J

000590 STOCK T(2;4)1Sn a/J

000594 STOCK T(2;8)26H a/T(2;8)26H a Tyrp1⁺/Tyrp1^b/J

000623 TR/DiEiJ

View Strains carrying a (104 strains)

Strains carrying other alleles of a

003301 (C57BL/6J x C3H-Eya1^bor)F1/J

000251 AEJ.Cg-a^e +/a Gdf5^bp-H/J

000202 AEJ/Gn-bd/J

000199 AEJ/GnLeJ

000433 B10.C-H3^c H13^? A/(28NX)SnJ

000427 B10.CE-H13^b A^w/(30NX)SnJ

000423 B10.KR-H13^? A/SnJ

000420 B10.LP-H13^b A^w/Sn

000477 B10.PA-Pldn^pa H3^e a^t/SnJ

000419 B10.UW-H3^b we Pax1^un a^t/SnJ

000593 B6 x B6CBCa A^w-J/A-Grid2^Lc T(2;6)7Ca Mitf^Mi-wh/J

000502 B6 x B6CBCa A^w-J/A-Myo5a^flr Gnb5^flr/J

000599 B6 x B6CBCa A^w-J/A-T(5;13)264Ca Kit^W-v/J

002083 B6 x B6EiC3 a/A-T(7;16)235Dn/J

000507 B6 x B6EiC3 a/A-Otc^spf/J

003759 B6 x B6EiC3Sn a/A-T(10;16)232Dn/J

002071 B6 x B6EiC3Sn a/A-T(11;17)202Dn/J

002113 B6 x B6EiC3Sn a/A-T(11A2;16B3)238Dn/J

002068 B6 x B6EiC3Sn a/A-T(11B1;16B5)233Dn/J

002069 B6 x B6EiC3Sn a/A-T(14E4or5;16B5)225Dn/J

001926 B6 x B6EiC3Sn a/A-T(15;16)198Dn/J

001832 B6 x B6EiC3Sn a/A-T(15E;16B1)60Dn/J

003758 B6 x B6EiC3Sn a/A-T(16C3-4;17A2)65Dn/J

001833 B6 x B6EiC3Sn a/A-T(1C2;16C3)45Dn/J

001903 B6 x B6EiC3Sn a/A-T(6F;18C)57Dn/J

001535 B6 x B6EiC3Sn a/A-T(8A4;12D1)69Dn/J

001831 B6 x B6EiC3Sn a/A-T(8C3;16B5)164Dn/J

002016 B6(Cg)-A^w-J Eda^Ta-6J Chr Y^B6-Sxr/EiJ

000552 B6-A^w-J-Eda^Ta-6J.Cg-Sxr

001730 B6-A^w-J-Eda^Ta-6J.Cg-Sxr^b Hya^-/J

000841 B6-A^w-J.CBy-Eda^Ta-By/J

001809 B6-A^w-J.Cg-Eda^Ta-6J +/+ Ar^Tfm/J

000600 B6-Gpi1^b x B6CBCa A^w-J/A-T(7;15)9H Gpi1^a/J

000769 B6.C/(HZ18)By-a^t-44J/J

000203 B6.C3-A^iy/a/J

000017 B6.C3-A^vy/J

001572 B6.C3-a^m-J/J

000628 B6.CE-A Amy1^b Amy2a5^b/J

000021 B6.Cg-A^y/J

100409 B6129PF1/J-A^w-J/A^w

004200 B6;CBACa A^w-J/A-Npr2^cn-2J/GrsrJ

000505 B6C3 A^w-J/A-Muted^mu/J

000604 B6C3 a/A-T(10;13)199H +/+ Lyst^bg-J/J or Lyst^bg-2J/J

000065 B6C3Fe a/a-we Pax1^un a^t/J

000314 B6CBACa A^w-J/A-Eda^Ta/J-XO

000501 B6CBACa A^w-J/A-Aifm1^Hq/J

001046 B6CBACa A^w-J/A-Grid2^Lc/J

000500 B6CBACa A^w-J/A-Gs/J

002703 B6CBACa A^w-J/A-Hydin^hy3/J

000247 B6CBACa A^w-J/A-Kcnj6^wv/J

000287 B6CBACa A^w-J/A-Plp1^jp Eda^Ta/J

000515 B6CBACa A^w-J/A-Sfn^Er/J

000242 B6CBACa A^w-J/A-spc/J

000288 B6CBACa A^w-J/A-we a Mafb^kr/J

001201 B6CBACaF1/J-A^w-J/A

001752 B6CBCa A^w-J/A-T(7;15)9H/J

006450 B6EiC3 a/A-Vss/GrsrJ

000557 B6EiC3-+ a/Lnp^Ul A/J

000504 B6EiC3Sn a/A-Cacnb4^lh/J

000553 B6EiC3Sn a/A-Egfr^wa2 Wnt3a^vt/J

001811 B6EiC3Sn a/A-Otc^spf-ash/J

002343 B6EiC3Sn a/A-Otc^spf/J

001923 B6EiC3Sn a/A-Ts(4¹⁷)2Lws Tim^T(4;17)3Lws/J

001875 B6EiC3SnF1/J

000200 C3FeB6 A/A^w-J-Ank^ank/J

000638 C3FeB6 A/A^w-J-Spnb4^qv-J/J

001203 C3FeB6F1/J A/A^w-J

001272 C3H/HeSnJ-A^hvy/J

000099 C3HeB/FeJ-A^vy/J

000338 C57BL/6J A^w-J-Eda^Ta-6J/J

000258 C57BL/6J-Aⁱ/a/J

000774 C57BL/6J-A^sy/a/J

000569 C57BL/6J-A^w-J-Eda^Ta +/+ Ar^Tfm/J

000051 C57BL/6J-A^w-J/J

000055 C57BL/6J-a^t-33J/J

000070 C57BL/6J-a^td/J

002468 KK.Cg-A^y/J

000262 LS/LeJ

000283 LT.CAST-A/J

001759 STOCK A Tyr^c Sha/J

001427 STOCK A^w us/J

View Strains carrying other alleles of a (81 strains)

Phenotype

Phenotype Information

View Related Disease (OMIM) Terms

Related Disease (OMIM) Terms

NOT Contractural Arachnodactyly, Congenital; CCA - No similarity to the expected human disease phenotype was found.⁴

⁴ One or more human genes are associated with this human disease. The mouse genotype may involve mutations to orthologs of one or more of those genes, but the phenotype did not resemble the disease.

View Mammalian Phenotype Terms

Mammalian Phenotype Terms
assigned by genotype

The following phenotype information may relate to a genetic background differing from this JAX^® Mice strain.
sy/sy
Background Not Specified
lethality-postnatal

postnatal lethality (MGI Ref ID J:208)

within 1 month of birth

behavior/neurological phenotype

abnormal motor capabilities/coordination/movement (MGI Ref ID J:208)

circling (MGI Ref ID J:208)

head bobbing (MGI Ref ID J:208)

hearing/vestibular/ear phenotype

abnormal ear morphology (MGI Ref ID J:13002)

abnormal membranous labyrinth (MGI Ref ID J:13002)

development of excessive mesenchymal tissue followed by collapse of endolymphatic space and degeneration of membraneous labyrinth

abnormal otic capsule morphology (MGI Ref ID J:13002)

abnormal semicircular canal (MGI Ref ID J:13002)

thin semicircular canals

abnormal hearing physiology (MGI Ref ID J:13002)

deafness (MGI Ref ID J:208)

circling (MGI Ref ID J:208)

head bobbing (MGI Ref ID J:208)

limbs/digits/tail phenotype

abnormal digit morphology (MGI Ref ID J:208)

syndactyly (MGI Ref ID J:208)

variable penetrance

usually of digits 2 and 3 or 3 and 4

decreased diameter of long bones (MGI Ref ID J:12945)

thin long bones

skeleton phenotype

abnormal axial skeleton morphology (MGI Ref ID J:12945)

abnormal sacral vertebrae morphology (MGI Ref ID J:12945)

abnormal scapula morphology (MGI Ref ID J:12945)

abnormal skeleton development (MGI Ref ID J:12945)

decreased bone density (MGI Ref ID J:12945)

decreased diameter of long bones (MGI Ref ID J:12945)

thin long bones

synostosis (MGI Ref ID J:12945)

synostosis of phalanges

variable penetrance

View Research Applications

Research Applications
This mouse can be used to support research in many areas including:
sy related

Cell Biology Research
Defects in Cell Adhesion Molecules
Defects in Extracellular Matrix Molecules
Genes Regulating Growth and Proliferation

Developmental Biology Research
Defects in Cell Adhesion Molecules
Defects in Extracellular Matrix Molecules
Skeletal Defects
syndactyly

Mouse/Human Gene Homologs
congenital contractural arachnodactyly

Neurobiology Research
Vestibular and Hearing Defects

Sensorineural Research
Vestibular and Hearing Defects

Genes & Alleles

Gene & Allele Information


Allele Symbol		a
Allele Name		nonagouti
Allele Type		Spontaneous

Allele Symbol		sy
Allele Name		shaker with syndactylism
Allele Type		Radiation induced
Gene Symbol and Name		sy, shaker-with-syndactylism deletion region
Chromosome		18
Molecular Note		This deletion has been approximated to 1 cM region and consists of at least two genes. The gene responsible for deafness in the original sy mutant mouse and the ns allele has been identifed as Slc12a2. The gene responsible for the abnormal foot morphology seen in the fused phalanges alleles and the original sy mutant has been identified as Fbn2. [MGI Ref ID J:50578]

Genotyping

Genotyping Information

This strain will not have a genotyping protocol or one is not currently available.

Helpful Links

Genotyping resources and troubleshooting

References

Additional References

Arteaga-Solis E; Gayraud B; Lee SY; Shum L; Sakai L; Ramirez F. 2001. Regulation of limb patterning by extracellular microfibrils. J Cell Biol 154(2):275-81. [PubMed: 11470817] [MGI Ref ID J:70592]

Chaudhry SS; Gazzard J; Baldock C; Dixon J; Rock MJ; Skinner GC; Steel KP; Kielty CM; Dixon MJ. 2001. Mutation of the gene encoding fibrillin-2 results in syndactyly in mice. Hum Mol Genet 10(8):835-43. [PubMed: 11285249] [MGI Ref ID J:68881]
sy related

Chaudhry SS; Gazzard J; Baldock C; Dixon J; Rock MJ; Skinner GC; Steel KP; Kielty CM; Dixon MJ. 2001. Mutation of the gene encoding fibrillin-2 results in syndactyly in mice. Hum Mol Genet 10(8):835-43. [PubMed: 11285249] [MGI Ref ID J:68881]

Deol MS. 1963. The development of the inner ear in mice homozygous for shaker-with-syndactylism. J Embryol Exp Morphol 11(3):493-512. [PubMed: 14061956] [MGI Ref ID J:13002]

Dixon MJ; Gazzard J; Chaudhry SS; Sampson N; Schulte BA; Steel KP. 1999. Mutation of the Na-K-Cl co-transporter gene Slc12a2 results in deafness in mice. Hum Mol Genet 8(8):1579-84. [PubMed: 10401008] [MGI Ref ID J:56631]

Gruneberg H. 1956. Genetical studies on the skeleton of the mouse. XVIII. Three genes for syndactylism. J Genet 54:113-145. [MGI Ref ID J:13049]

Gruneberg H. 1962. Genetical studies on the skeleton of the mouse. XXXII. The development of shaker with syndactylism. Genet Res 3:157-166. [MGI Ref ID J:12945]

Hertwig P. 1942. Neue Mutationen und Koppelungsgruppen bei der Hausmaus Z Indukt Abstamm Vererbungsl 80:220-246. [MGI Ref ID J:208]

Johnson KR; Cook SA; Zheng QY. 1998. The original shaker-with-syndactylism mutation (sy) is a contiguous gene deletion syndrome. Mamm Genome 9(11):889-92. [PubMed: 9799839] [MGI Ref ID J:50578]

Health & husbandry

Health & Colony Maintenance Information

Currently there no information available for this strain. This may be due to the supply level of this strain.

Purchasing information

Pricing, Supply Level & Notes, Controls, General Terms & Conditions

Pricing

Pricing for USA, Canada and Mexico shipping destinations

Price (US dollars $)

Cryorecovery Fee $1900.00

Animals Provided
At least two mice that carry the mutation (if it is a mutant strain) will be provided. Their genotypes may not reflect those discussed in the strain description. Please inquire for possible genotypes and see additional details below.

	Price (US dollars $)
Cryorecovery Fee	$1900.00

Additional Supply Details

Pricing for International shipping destinations

Price (US dollars $)

Cryorecovery Fee $2470.00

Animals Provided
At least two mice that carry the mutation (if it is a mutant strain) will be provided. Their genotypes may not reflect those discussed in the strain description. Please inquire for possible genotypes and see additional details below.

	Price (US dollars $)
Cryorecovery Fee	$2470.00

Additional Supply Details

Supply Details

Standard Supply	Cryopreserved. Ready for recovery. Please refer to pricing and supply notes for further information.
Supply Notes	Cryorecovery of Strains Needing Progeny Testing. At least two untested males and two untested females (two pairs) will be recovered (eight or more mice is typical). The total number of animals provided, their gender and genotype will vary. Untested animals typically are available to ship between 13 and 16 weeks from the date of your order. If the first recovery attempt is unsuccessful, a second recovery will be done, extending the overall recovery time to approximately 25 weeks. Progeny testing is required to identify the genotype of mice of this strain, as a genotyping assay is not available. This type of testing involves breeding the recovered animals and assessing the phenotype of the offspring in order to identify animals carrying the mutation of interest. We can perform the progeny testing for you as a service or we can ship all recovered animals to you for progeny testing at your facility. If you perform the progeny testing, there is NO guarantee that a carrier will be identified. If we perform progeny testing as a service, additional breeding time will be required. In this case, when a male and female (one pair) are identified that carry the mutation, they and their offspring will be shipped. Delivery time for strains requiring progeny testing often exceeds 25 weeks and may take 12 months or more due to the difficulties in breeding some strains. The progeny testing cost is in addition to the recovery cost and is based on the number of boxes used and the time taken to produce the mice identified as carrying the mutation. Please note that identified pairs may not reflect the mating scheme utilized by The Jackson Laboratory prior to cryopreservation of the strain. Mating schemes are sometimes modified for successful cryopreservation. Please contact Customer Service for more information on the cost of progeny testing for a strain: Tel: 1-800-422-6423 (from U.S.A., Canada and Puerto Rico only) or 1-207-288-5845 (from any location). The Jackson Laboratory cannot guarantee the reproductive success of mice shipped to your facility. If the mice are lost after the first three days (post-arrival) or do not produce progeny at your facility, a new order and fee will be necessary. *Cryorecovery to establish a Dedicated Supply for greater quantities of mice.* Mice recovered can be used to establish a dedicated colony to contractually supply you mice according to your requirements. Price by quotation. For more information on Dedicated Supply, please contact JAX^® Services, Tel: 1-800-422-6423 (from U.S.A., Canada or Puerto Rico only) or 1-207-288-5845 (from any location). Genomic DNA is available for this strain from the Mouse DNA Resource.

Standard Supply

Cryopreserved. Ready for recovery. Please refer to pricing and supply notes for further information.

Supply Notes

Cryorecovery of Strains Needing Progeny Testing.
At least two untested males and two untested females (two pairs) will be recovered (eight or more mice is typical). The total number of animals provided, their gender and genotype will vary. Untested animals typically are available to ship between 13 and 16 weeks from the date of your order. If the first recovery attempt is unsuccessful, a second recovery will be done, extending the overall recovery time to approximately 25 weeks.
Progeny testing is required to identify the genotype of mice of this strain, as a genotyping assay is not available. This type of testing involves breeding the recovered animals and assessing the phenotype of the offspring in order to identify animals carrying the mutation of interest. We can perform the progeny testing for you as a service or we can ship all recovered animals to you for progeny testing at your facility. If you perform the progeny testing, there is NO guarantee that a carrier will be identified. If we perform progeny testing as a service, additional breeding time will be required. In this case, when a male and female (one pair) are identified that carry the mutation, they and their offspring will be shipped. Delivery time for strains requiring progeny testing often exceeds 25 weeks and may take 12 months or more due to the difficulties in breeding some strains. The progeny testing cost is in addition to the recovery cost and is based on the number of boxes used and the time taken to produce the mice identified as carrying the mutation. Please note that identified pairs may not reflect the mating scheme utilized by The Jackson Laboratory prior to cryopreservation of the strain. Mating schemes are sometimes modified for successful cryopreservation. Please contact Customer Service for more information on the cost of progeny testing for a strain: Tel: 1-800-422-6423 (from U.S.A., Canada and Puerto Rico only) or 1-207-288-5845 (from any location). The Jackson Laboratory cannot guarantee the reproductive success of mice shipped to your facility. If the mice are lost after the first three days (post-arrival) or do not produce progeny at your facility, a new order and fee will be necessary.
Cryorecovery to establish a Dedicated Supply for greater quantities of mice.
Mice recovered can be used to establish a dedicated colony to contractually supply you mice according to your requirements. Price by quotation. For more information on Dedicated Supply, please contact JAX^® Services, Tel: 1-800-422-6423 (from U.S.A., Canada or Puerto Rico only) or 1-207-288-5845 (from any location).
Genomic DNA is available for this strain from the Mouse DNA Resource.

Payment Terms and Conditions

Terms are granted by individual review and stated on the customer invoice(s) and account statement. These transactions are payable in U.S. currency within the granted terms. Payment for services, products, shipping containers, and shipping costs that are rendered are expected within the payment terms indicated on the invoice or stated by contract. Invoices and account balances in arrears of stated terms may result in The Jackson Laboratory pursuing collection activities including but not limited to outside agencies and court filings.

See Terms of Use tab for General Terms and Conditions

The Jackson Laboratory's Genotype Promise

The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX^® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX^® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX^® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.

Ordering and Purchasing Information

Purchasing Information
JAX^® Mice Orders
Surgical Services

Contact Information
Orders & Technical Support
Tel: 1-800-422-6423 or 1-207-288-5845
Fax: 1-207-288-6150
Technical Support Email Form

Terms of Use

General Terms and Conditions

Contact information

General inquiries

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phone:	207-288-6470
fax:	207-288-6655

JAX^® Mice, Products & Services Conditions of Use

"MICE" means mouse strains, their progeny derived by inbreeding or crossbreeding, unmodified derivatives from mouse strains or their progeny supplied by The Jackson Laboratory ("JACKSON"). "PRODUCTS" means biological materials supplied by JACKSON, and their derivatives. "RECIPIENT" means each recipient of MICE, PRODUCTS, or services provided by JACKSON including each institution, its employees and other researchers under its control. MICE or PRODUCTS shall not be: (i) used for any purpose other than the internal research, (ii) sold or otherwise provided to any third party for any use, or (iii) provided to any agent or other third party to provide breeding or other services. Acceptance of MICE or PRODUCTS from JACKSON shall be deemed as agreement by RECIPIENT to these conditions, and departure from these conditions requires JACKSON's prior written authorization.

No Warranty

MICE, PRODUCTS AND SERVICES ARE PROVIDED “AS IS”. JACKSON EXTENDS NO WARRANTIES OF ANY KIND, EITHER EXPRESS, IMPLIED, OR STATUTORY, WITH RESPECT TO MICE, PRODUCTS OR SERVICES, INCLUDING ANY IMPLIED WARRANTY OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE, OR ANY WARRANTY OF NON-INFRINGEMENT OF ANY PATENT, TRADEMARK, OR OTHER INTELLECTUAL PROPERTY RIGHTS.

In case of dissatisfaction for a valid reason and claimed in writing by a purchaser within ninety (90) days of receipt of mice, products or services, JACKSON will, at its option, provide credit or replacement for the mice or product received or the services provided.

No Liability

In no event shall JACKSON, its trustees, directors, officers, employees, and affiliates be liable for any causes of action or damages, including any direct, indirect, special, or consequential damages, arising out of the provision of MICE, PRODUCTS or services, including economic damage or injury to property and lost profits, and including any damage arising from acts or negligence on the part of JACKSON, its agents or employees. In purchasing or receiving MICE, PRODUCTS or services from JACKSON, purchaser or recipient, or any party claiming by or through them, expressly releases and discharges JACKSON from all such causes of action or damages, and further agrees to defend and indemnify JACKSON from any costs or damages arising out of any third party claims.

MICE and PRODUCTS are to be used in a safe manner and in accordance with all applicable governmental rules and regulations.

The foregoing represents the General Terms and Conditions applicable to JACKSON’s MICE, PRODUCTS or services. In addition, special terms and conditions of sale of certain MICE, PRODUCTS or services may be set forth separately in JACKSON web pages, catalogs, price lists, contracts, and/or other documents, and these special terms and conditions shall also govern the sale of these MICE, PRODUCTS and services by JACKSON, and by its licensees and distributors.

Acceptance of delivery of MICE, PRODUCTS or services shall be deemed agreement to these terms and conditions. No purchase order or other document transmitted by purchaser or recipient that may modify the terms and conditions hereof, shall be in any way binding on JACKSON, and instead the terms and conditions set forth herein, including any special terms and conditions set forth separately, shall govern the sale of MICE, PRODUCTS or services by JACKSON.

003879	B10;TFLe-a/a T tf/+ tf/J
001538	B6 x B6C3Sn a/A-T(1;9)27H/J
000916	B6 x B6C3Sn a/A-T(5;12)31H/J
000602	B6 x B6C3Sn a/A-T(8;16)17H/J
000618	B6 x FSB/GnEi a/a Ctsl^fs/J
000577	B6 x STOCK a Oca2^p Hps5^ru2 Ednrb^s/J
000601	B6 x STOCK a/a T(7;18)50H/J
000592	B6 x STOCK T(2;4)13H a/J
000001	B6.C3 A/a Mgrn1^md/J
000231	B6;C3Fe a/a-Csf1^op/J
000785	B6;D2-a Es1^e/EiJ
000604	B6C3 a/A-T(10;13)199H +/+ Lyst^bg-J/J or Lyst^bg-2J/J
002807	B6C3Fe a/a-Meox2^fla/J
000224	B6C3Fe a/a-Scyl1^mdf/J
001037	B6C3Fe a/a-Agtpbp1^pcd/J
000221	B6C3Fe a/a-Alx4^lst-J/J
002062	B6C3Fe a/a-Atp7a^Mo-8J/J
001756	B6C3Fe a/a-Cacng2^stg/J
001815	B6C3Fe a/a-Col1a2^oim/J
000209	B6C3Fe a/a-Dh/J
000211	B6C3Fe a/a-Dst^dt-J/J
000210	B6C3Fe a/a-Edar^dl-J/J
000207	B6C3Fe a/a-Edaradd^cr/J
000182	B6C3Fe a/a-Eef1a2^wst/J
001278	B6C3Fe a/a-Glra1^spd/J
000241	B6C3Fe a/a-Glrb^spa/J
002875	B6C3Fe a/a-Hoxd13^spdh/J
000304	B6C3Fe a/a-Krt71^Ca Scn8a^med-J/J
000226	B6C3Fe a/a-Large^myd/J
000636	B6C3Fe a/a-Lmx1a^dr-J/J
001280	B6C3Fe a/a-Lse/J
001573	B6C3Fe a/a-Mitf^Mi/J
001035	B6C3Fe a/a-Napa^hyh/J
000181	B6C3Fe a/a-Otog^twt/J
000278	B6C3Fe a/a-Papss2^bm Hps1^ep Hps6^ru/J
000205	B6C3Fe a/a-Papss2^bm/J
002078	B6C3Fe a/a-Pcdh15^av-2J/J
000246	B6C3Fe a/a-Pitpna^vb/J
001430	B6C3Fe a/a-Ptch1^mes/J
000506	B6C3Fe a/a-Qk^qk/J
000235	B6C3Fe a/a-Reln^rl/J
000237	B6C3Fe a/a-Rora^sg/J
000290	B6C3Fe a/a-Sox10^Dom/J
000230	B6C3Fe a/a-Tcirg1^oc/J
003612	B6C3Fe a/a-Trak1^hyrt/J
001512	B6C3Fe a/a-Ttn^mdm/J
001607	B6C3Fe a/a-Unc5c^rcm/J
000005	B6C3Fe a/a-Wc/J
000243	B6C3Fe a/a-Wnt1^sw/J
000248	B6C3Fe a/a-Xpl/J
001750	B6C3Fe a/a-Xs^J/J
000624	B6C3Fe a/a-anx/J
008044	B6C3Fe a/a-bpck/J
003020	B6C3Fe a/a-dep/J
002018	B6C3Fe a/a-din/J
002339	B6C3Fe a/a-nma/J
000240	B6C3Fe a/a-soc/J
001055	B6C3Fe a/a-tip/J
000245	B6C3Fe a/a-tn/J
000296	B6C3Fe-a/a Hoxa13^Hd Mcoln3^Va-J/J
000019	B6C3Fe-a/a-Itpr1^opt/J
001022	B6C3FeF1/J a/a
006450	B6EiC3 a/A-Vss/GrsrJ
000971	B6EiC3 a/A-Och/J
000551	B6EiC3 a/A-Tbx15^de-H/J
000557	B6EiC3-+ a/Lnp^Ul A/J
000503	B6EiC3Sn a/A-Gy/J
001811	B6EiC3Sn a/A-Otc^spf-ash/J
002343	B6EiC3Sn a/A-Otc^spf/J
000391	B6EiC3Sn a/A-Pax6^Sey-Dey/J
001924	B6EiC3Sn a/A-Ts(17¹⁶)65Dn
001923	B6EiC3Sn a/A-Ts(4¹⁷)2Lws Tim^T(4;17)3Lws/J
000225	C3FeLe.B6 a/a-Ptpn6^me/J
008425	C3FeLe.B6-a Trl/J
000198	C3FeLe.B6-a/J
000291	C3FeLe.Cg-a/a Hm Kitl^Sl Krt71^Ca-J/J
001886	C3HeB/FeJLe a/a-gnd/J
000584	C57BL/6J-+ T(1;2)5Ca/a +/J
000284	CWD/LeJ
000670	DBA/1J
000671	DBA/2J
001057	HPT/LeJ
000260	JGBF/LeJ
000265	MY/HuLeJ
000308	SSL/LeJ
000994	STOCK a Myo5a^d Mreg^dsu/J
000064	STOCK a Tyrp1^b Si^si/J
002238	STOCK a Tyrp1^b shmy/J
001433	STOCK a skt/J
000579	STOCK a tp/J
000319	STOCK a us/J
002648	STOCK a/a Cln6^nclf/J
000317	STOCK a/a Egfr^wa2/J
000302	STOCK a/a Mitf^Mi-wh +/+ Itpr1^opt/J
000286	STOCK a/a Myo5a^d fd/+ +/J
000206	STOCK a/a Tyr^c-h/J
001432	STOCK a/a Tyrp1^b sks/Tyrp1^b +/J
000281	STOCK a/a ma Flg^ft/ma Flg^ft/J
000312	STOCK stb + a/+ Fign^fi a/J
000596	STOCK T(2;11)30H/+ x AEJ-a Gdf5^bp-H/J or A/J-a Gdf5^bp-J/J
000970	STOCK T(2;16)28H A/T(2;16)28H a/J
000590	STOCK T(2;4)1Sn a/J
000594	STOCK T(2;8)26H a/T(2;8)26H a Tyrp1⁺/Tyrp1^b/J
000623	TR/DiEiJ

003301	(C57BL/6J x C3H-Eya1^bor)F1/J
000251	AEJ.Cg-a^e +/a Gdf5^bp-H/J
000202	AEJ/Gn-bd/J
000199	AEJ/GnLeJ
000433	B10.C-H3^c H13^? A/(28NX)SnJ
000427	B10.CE-H13^b A^w/(30NX)SnJ
000423	B10.KR-H13^? A/SnJ
000420	B10.LP-H13^b A^w/Sn
000477	B10.PA-Pldn^pa H3^e a^t/SnJ
000419	B10.UW-H3^b we Pax1^un a^t/SnJ
000593	B6 x B6CBCa A^w-J/A-Grid2^Lc T(2;6)7Ca Mitf^Mi-wh/J
000502	B6 x B6CBCa A^w-J/A-Myo5a^flr Gnb5^flr/J
000599	B6 x B6CBCa A^w-J/A-T(5;13)264Ca Kit^W-v/J
002083	B6 x B6EiC3 a/A-T(7;16)235Dn/J
000507	B6 x B6EiC3 a/A-Otc^spf/J
003759	B6 x B6EiC3Sn a/A-T(10;16)232Dn/J
002071	B6 x B6EiC3Sn a/A-T(11;17)202Dn/J
002113	B6 x B6EiC3Sn a/A-T(11A2;16B3)238Dn/J
002068	B6 x B6EiC3Sn a/A-T(11B1;16B5)233Dn/J
002069	B6 x B6EiC3Sn a/A-T(14E4or5;16B5)225Dn/J
001926	B6 x B6EiC3Sn a/A-T(15;16)198Dn/J
001832	B6 x B6EiC3Sn a/A-T(15E;16B1)60Dn/J
003758	B6 x B6EiC3Sn a/A-T(16C3-4;17A2)65Dn/J
001833	B6 x B6EiC3Sn a/A-T(1C2;16C3)45Dn/J
001903	B6 x B6EiC3Sn a/A-T(6F;18C)57Dn/J
001535	B6 x B6EiC3Sn a/A-T(8A4;12D1)69Dn/J
001831	B6 x B6EiC3Sn a/A-T(8C3;16B5)164Dn/J
002016	B6(Cg)-A^w-J Eda^Ta-6J Chr Y^B6-Sxr/EiJ
000552	B6-A^w-J-Eda^Ta-6J.Cg-Sxr
001730	B6-A^w-J-Eda^Ta-6J.Cg-Sxr^b Hya^-/J
000841	B6-A^w-J.CBy-Eda^Ta-By/J
001809	B6-A^w-J.Cg-Eda^Ta-6J +/+ Ar^Tfm/J
000600	B6-Gpi1^b x B6CBCa A^w-J/A-T(7;15)9H Gpi1^a/J
000769	B6.C/(HZ18)By-a^t-44J/J
000203	B6.C3-A^iy/a/J
000017	B6.C3-A^vy/J
001572	B6.C3-a^m-J/J
000628	B6.CE-A Amy1^b Amy2a5^b/J
000021	B6.Cg-A^y/J
100409	B6129PF1/J-A^w-J/A^w
004200	B6;CBACa A^w-J/A-Npr2^cn-2J/GrsrJ
000505	B6C3 A^w-J/A-Muted^mu/J
000604	B6C3 a/A-T(10;13)199H +/+ Lyst^bg-J/J or Lyst^bg-2J/J
000065	B6C3Fe a/a-we Pax1^un a^t/J
000314	B6CBACa A^w-J/A-Eda^Ta/J-XO
000501	B6CBACa A^w-J/A-Aifm1^Hq/J
001046	B6CBACa A^w-J/A-Grid2^Lc/J
000500	B6CBACa A^w-J/A-Gs/J
002703	B6CBACa A^w-J/A-Hydin^hy3/J
000247	B6CBACa A^w-J/A-Kcnj6^wv/J
000287	B6CBACa A^w-J/A-Plp1^jp Eda^Ta/J
000515	B6CBACa A^w-J/A-Sfn^Er/J
000242	B6CBACa A^w-J/A-spc/J
000288	B6CBACa A^w-J/A-we a Mafb^kr/J
001201	B6CBACaF1/J-A^w-J/A
001752	B6CBCa A^w-J/A-T(7;15)9H/J
006450	B6EiC3 a/A-Vss/GrsrJ
000557	B6EiC3-+ a/Lnp^Ul A/J
000504	B6EiC3Sn a/A-Cacnb4^lh/J
000553	B6EiC3Sn a/A-Egfr^wa2 Wnt3a^vt/J
001811	B6EiC3Sn a/A-Otc^spf-ash/J
002343	B6EiC3Sn a/A-Otc^spf/J
001923	B6EiC3Sn a/A-Ts(4¹⁷)2Lws Tim^T(4;17)3Lws/J
001875	B6EiC3SnF1/J
000200	C3FeB6 A/A^w-J-Ank^ank/J
000638	C3FeB6 A/A^w-J-Spnb4^qv-J/J
001203	C3FeB6F1/J A/A^w-J
001272	C3H/HeSnJ-A^hvy/J
000099	C3HeB/FeJ-A^vy/J
000338	C57BL/6J A^w-J-Eda^Ta-6J/J
000258	C57BL/6J-Aⁱ/a/J
000774	C57BL/6J-A^sy/a/J
000569	C57BL/6J-A^w-J-Eda^Ta +/+ Ar^Tfm/J
000051	C57BL/6J-A^w-J/J
000055	C57BL/6J-a^t-33J/J
000070	C57BL/6J-a^td/J
002468	KK.Cg-A^y/J
000262	LS/LeJ
000283	LT.CAST-A/J
001759	STOCK A Tyr^c Sha/J
001427	STOCK A^w us/J

Strain Name:

B6C3Fe a/a-sy/J

Stock Number:

000063

Availability:

Cryopreserved - Ready for recovery

Strain Information

Related Strains

Phenotype Information

sy/sy

Gene & Allele Information

Genotyping Information

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See Terms of Use tab for General Terms and Conditions

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JAX® Mice, Products & Services Conditions of Use

No Warranty

No Liability

JAX^® Mice, Products & Services Conditions of Use