JAX Mice Database - 000462 B10.D2-H2<d>/n2SnJ

Strain Name:	B10.D2-H2^d/n2SnJ
Stock Number:	000462
Availability:	Cryopreserved - Ready for recovery

Description
Phenotype
Genes & alleles
Genotyping
Health & husbandry
References
Purchasing information
Terms of Use

Description

The genotypes of the animals provided may not reflect those discussed in the strain description or the mating scheme utilized by The Jackson Laboratory prior to cryopreservation. Please inquire for possible genotypes for this specific strain.

Strain Information

Type Congenic; Major Histocompatibility Congenic; Mutant Strain;
Additional information on Genetically Engineered and Mutant Mice.

Visit our online Nomenclature tutorial.

Additional information on Congenic nomenclature.

Species laboratory mouse

Background Strain C57BL/10Sn

Donor Strain DBA/2

Generation F?+1p

Control Information

	Control
	000666 C57BL/10SnJ

Considerations for Choosing Controls

Related Strains

Strains carrying H2^d allele

005308 B10.Cg-H2^d Tg(TcraCl4,TcrbCl4)1Shrm/ShrmJ

005534 B10.Cg-H2^d Tg(Ins2-HA)165Bri/ShrmJ

005895 B10.Cg-Thy1^a H2^d Tg(TcraCl1,TcrbCl1)1Shrm/J

000460 B10.D2-Hc⁰ H2^d H2-T18^c/o2SnJ

000461 B10.D2-Hc⁰ H2^d H2-T18^c/oSnJ

000463 B10.D2-Hc¹ H2^d H2-T18^c/nSnJ

003147 B10.D2-Hc¹ H2^d H2-T18^c/nSnJ-Tg(DO11.10)10Dlo/J

000360 B6.C-H2^d Mdmg1^BALB/cBy/aByJ

000359 B6.C-H2^d/bByJ

001893 BRVR.D2-H2^d/J

000437 D1.C-H2^d H2-T18^c/SnJ

003153 WLC.C-H2^d.GR-Mtv2/MorJ

003154 WLC.C-H2^d/MorJ

View Strains carrying H2^d (13 strains)

Strains carrying other alleles of H2

006500 129.NOD-(D17Mit175-H2)/J

001649 A.BY H2^bc H2-T18^f/SnJ-Dstn^corn1/J

000140 A.BY-H2^bc H2-T18^f/SnJ

000472 A.CA-H2^f H2-T18^a/SnJ

000471 A.SW-H2^s H2-T18^b/SnJ

001066 A.TH-H2^t2/SfDvEgMobJ

001067 A.TL-H2^t1/SfDvEgMobJ

002089 AK.B6-H2^b Fv1^b/J

002090 AK.B6-H2^b/J

001094 AK.L-H2^b/1CyTyJ

001095 AK.L-H2^oz2/CyJ

001096 AK.L-H2^oz3/CyJ

000470 AK.M-H2^m H2-T18^a/nSnJ

003851 ALR.NOD-(D17Mit30-D17Mit123)/Lt

000469 B10.A-H2^a H2-T18^a/SgSnJ

000468 B10.A-H2^h2/(2R)SgSnJ

001150 B10.A-H2^h4/(4R)SgDvEgJ

001149 B10.A-H2ⁱ³/(3R)SgDvEgJ

000467 B10.A-H2ⁱ⁵ H2-T18^a/(5R)SgSnJ

000466 B10.AKM-H2^m H2-T18^a/SnJ

001954 B10.AQR-H2^y1/KljMcdJ

000465 B10.BR-H2^k H2-T18^a/SgSnJ

004804 B10.BR-H2^k H2-T18^a/SgSnJJrep

006446 B10.Cg H2^h4-Sh3pxd2b^nee/GrsrJ

010514 B10.Cg-H2^g Tg(Cd4-Klra1)6295Dl/J

006100 B10.Cg-H2^k Tg(NFkB/Fos-luc)26Rinc/J

006102 B10.Cg-H2^k Tg(Il2/NFAT-luc)83Rinc/J

002024 B10.D1-H2^q/SgJ

001163 B10.D2-H2^bm23/EgJ

001164 B10.D2-H2^dm1/EgJ

001151 B10.D2-H2^g3/(103R)EgJ

001153 B10.D2-H2ⁱ⁷/(107R)EgJ

001152 B10.D2-H2^ia/(106R)EgJ

000464 B10.DA-H2^qp1 H2-T18^b/(80NS)SnJ

001823 B10.F-H2^bp5/(14R)J

001818 B10.F-H2^pb1/(13R)J

001012 B10.HTG-H2^g/2CyJ

000999 B10.HTG-H2^g/3CyJ

001894 B10.LG-H2^ar1/J

000459 B10.M-H2^f H2-T18^a^?/SnJ

002225 B10.M-H2^f/nMob Fmn1^ld-2J/J

001068 B10.M-H2^f/nMobJ

000739 B10.M-H2^fm2/MobJ

001154 B10.MBR-H2^bq1/SxEgJ

010972 B10.NOD-(rs13459152-rs13483054)/1107MrkJ

001825 B10.P-H2^kp1/(10R)SgJ

003199 B10.PL-H2^u H2-T18^a/(73NS)Sn-Tg(TCRA)B1Jg/J

003200 B10.PL-H2^u H2-T18^a/(73NS)Sn-Tg(TCRB)C14Jg/J

000458 B10.PL-H2^u H2-T18^a/(73NS)SnJ

003599 B10.RIII H2^r H2-T18^b/(71NS)Sn-Ap3b1^pe-11J/J

000457 B10.RIII-H2^r H2-T18^b/(71NS)SnJ

001069 B10.RIII-H2^r/(71NS)nMobJ

001760 B10.S-H2^as1/(8R)/J

001953 B10.S-H2^s/SgMcdJ

001817 B10.S-H2^sm1/(12R)SgJ

001650 B10.S-H2^t4/(9R)/J

000456 B10.SM H2^v H2-T18^b/(70NS)Sn-cw/J

001155 B10.T-H2^y2/(6R)SgDvEgJ

000445 B10.WB-H2^j H2-T18^b/SnJ

000444 B10.Y-H2^pa H2-T18^c/SnJ

003483 B6 x B10.D1-H2^q/SgJ-Nox3^het-2J/J

003561 B6 x B10.PL-H2^u/(73NS)Sn-Hxl/J

002995 B6 x C.B10-H2^b/LiMcdJ-Fbn2^fp-2J/J

005717 B6(NOD) H2^g7-Sostdc1^shk/J

003584 B6.129S2-H2^dlAb1-Ea/J

001148 B6.AK-H2^k/FlaEgJ

001895 B6.AK-H2^k/J

001160 B6.C-H2^bm10/KhEgJ

001161 B6.C-H2^bm11/KhEgJ

000364 B6.C-H2^bm2/ByJ

000369 B6.C-H2^bm4/ByJ

001158 B6.C-H2^bm7/KhEgJ

001429 B6.C-H2^g6/J

005715 B6.Cg H2^g7-Tg(Ins2-CD80)3B7Flv/LwnJ

007958 B6.Cg-H2^b3/FlaCmwJ

007959 B6.Cg-H2^b4/FlaCmwJ

003068 B6.NOD-(Csf2-D11Mit42) (D17Mit21-D17Mit10)/J

003300 B6.NOD-(D17Mit21-D17Mit10)/LtJ

003069 B6.NOD-(D1Mit3-Bcl2) (D17Mit21-D17Mit10)/LtJ

003071 B6.NOD-(D1Mit5.1-D1Mit15) (D17Mit21-D17Mit10)/J

003067 B6.NOD-(D3Mit132-Tshb) (D17Mit21-D17Mit10)/J

003066 B6.NOD-(D6Mit54-D6Mit14) (D17Mit21-D17Mit10)/J

000944 B6.SJL-H2^b C3^c/2CyJ

000966 B6.SJL-H2^s C3^c/1CyJ

000945 B6.SW/1CyJ

003374 B6;129S2-H2^dlAb1-Ea/J

003240 B6;B10.A-H2^a-Tg(H2KmPCC)2939Stoe/J

002844 BALB.5R-H2ⁱ⁵/LilJ

001165 BALB/c-H2^dm2/KhEgJ

001041 BKS.B6-H2^b/J

001892 BRVR.B10-H2^b/J

002845 C.B-H2^b Tg(H2-D^d)D8Gja/LilJ

001952 C.B10-H2^b/LilMcdJ

001951 C.C3-H2^k/LilMcdJ

000443 C3.HTG-H2^g H2-T18^b^?/SnJ

000441 C3.JK-H2^j H2-T18^b/SnJ

000440 C3.LG-H2^ar1/CkcCyJ

000439 C3.NB-H2^p H2-T18^c^?/SnJ

000438 C3.SW-H2^b/SnJ

000473 C3H-H2^o2 C4b^b/SfSnJ

001156 C57BL/6J-H2^bm3/EgJ

001157 C57BL/6Kh-H2^bm5/KhEgJ

000436 D1.DA-H2^qp1/SnJ

000435 D1.LP-H2^b H2-T18^b^?/SnJ

000434 LP.RIII-H2^r H2-T18^b/SnJ

001383 LT.MA-Glo1^b H2^k/J

002591 NOD.B10Sn-H2^b/J

006935 NOD.Cg-H2^b thnh/J

004447 NOD.Cg-H2^h4/DilTacUmmJ

001626 NOD.NON-H2^nb1/LtJ

002032 NOD.SW-H2^q/J

001627 NON.NOD-H2^g7/LtJ

002974 STOCK Es1^e H2^d/J

001308 STOCK H2^473a/J

View Strains carrying other alleles of H2 (114 strains)

Phenotype

Phenotype Information

View Research Applications

Research Applications
This mouse can be used to support research in many areas including:
H2^d related

Immunology and Inflammation Research
CD Antigens, Antigen Receptors, and Histocompatibility Markers

Currently there is no phenotype information for this strain.

Genes & Alleles

Gene & Allele Information


Allele Symbol		H2^d
Allele Name		d variant
Allele Type		Spontaneous
Gene Symbol and Name		H2, histocompatibility-2, MHC
Chromosome		17
Gene Common Name(s)		H-2; MHC-II;
General Note		The d variant has been observed in the following strains: DBA/2, DBA/2J BALB/c, BALB/cByJ, BALB/cJ, C57BLKS, NZB.

Genotyping

Genotyping Information

This strain will not have a genotyping protocol or one is not currently available.

Helpful Links

Genotyping resources and troubleshooting

References

Additional References

H2^d related

Addis-Lieser E; Kohl J; Chiaramonte MG. 2005. Opposing regulatory roles of complement factor 5 in the development of bleomycin-induced pulmonary fibrosis. J Immunol 175(3):1894-902. [PubMed: 16034133] [MGI Ref ID J:107269]

Bakir HY; Tomiyama-Miyaji C; Watanabe H; Nagura T; Kawamura T; Sekikawa H; Abo T. 2006. Reasons why DBA/2 mice are resistant to malarial infection: expansion of CD3int B220+ gammadelta T cells with double-negative CD4- CD8- phenotype in the liver. Immunology 117(1):127-35. [PubMed: 16423048] [MGI Ref ID J:106141]

Bhadra S; Lozano MM; Payne SM; Dudley JP. 2006. Endogenous MMTV Proviruses Induce Susceptibility to Both Viral and Bacterial Pathogens. PLoS Pathog 2(12):e128. [PubMed: 17140288] [MGI Ref ID J:120299]

Buhlmann JE; Gonzalez M; Ginther B; Panoskaltsis-Mortari A; Blazar BR; Greiner DL; Rossini AA; Flavell R; Noelle RJ. 1999. Cutting edge: sustained expansion of CD8+ T cells requires CD154 expression by Th cells in acute graft versus host disease. J Immunol 162(8):4373-6. [PubMed: 10201970] [MGI Ref ID J:119788]

Chiorazzi N; Fox DA; Katz DH. 1977. Hapten-specific IgE antibody responses in mice. VII. Conversion of IgE non-responder strains to IgE responders by elimination of suppressor T cell activity. J Immunol 118(1):48-54. [PubMed: 299762] [MGI Ref ID J:5739]

Clarke SR; Barnden M; Kurts C; Carbone FR; Miller JF; Heath WR. 2000. Characterization of the ovalbumin-specific TCR transgenic line OT-I: MHC elements for positive and negative selection. Immunol Cell Biol 78(2):110-7. [PubMed: 10762410] [MGI Ref ID J:133645]

Croxford AL; Akilli-Ozturk O; Rieux-Laucat F; Forster I; Waisman A; Buch T. 2008. MHC-restricted T cell receptor signaling is required for alphabeta TCR replacement of the pre T cell receptor. Eur J Immunol 38(2):391-9. [PubMed: 18203137] [MGI Ref ID J:131357]

Dalloul AH; Ngo K; Fung-Leung WP. 1996. CD4-negative cytotoxic T cells with a T cell receptor alpha/beta intermediate expression in CD8-deficient mice. Eur J Immunol 26(1):213-8. [PubMed: 8566069] [MGI Ref ID J:112982]

El-Sawy T; Belperio JA; Strieter RM; Remick DG; Fairchild RL. 2005. Inhibition of polymorphonuclear leukocyte-mediated graft damage synergizes with short-term costimulatory blockade to prevent cardiac allograft rejection. Circulation 112(3):320-31. [PubMed: 15998678] [MGI Ref ID J:117219]

Fischer Lindahl K. 1997. On naming H2 haplotypes: functional significance of MHC class Ib alleles. Immunogenetics 46(1):53-62. [PubMed: 9148789] [MGI Ref ID J:41130]

Ford MS; Zhang ZX; Chen W; Zhang L. 2006. Double-negative T regulatory cells can develop outside the thymus and do not mature from CD8+ T cell precursors. J Immunol 177(5):2803-9. [PubMed: 16920915] [MGI Ref ID J:139556]

Fu G; Vallee S; Rybakin V; McGuire MV; Ampudia J; Brockmeyer C; Salek M; Fallen PR; Hoerter JA; Munshi A; Huang YH; Hu J; Fox HS; Sauer K; Acuto O; Gascoigne NR. 2009. Themis controls thymocyte selection through regulation of T cell antigen receptor-mediated signaling. Nat Immunol 10(8):848-56. [PubMed: 19597499] [MGI Ref ID J:151074]

Gershwin ME; Castles JJ; Ikeda RM; Erickson K; Montero J. 1979. Studies of congenitally immunologic mutant New Zealand mice. I. Autoimmune features of hereditarily asplenic (Dh/+) NZB mice; reduction of naturally occurring thymocytotoxic antibody and normal suppressor function. J Immunol 122(2):710-7. [PubMed: 310848] [MGI Ref ID J:12036]

Ghendler Y; Hussey RE; Witte T; Mizoguchi E; Clayton LK; Bhan AK; Koyasu S; Chang HC; Reinherz EL. 1997. Double-positive T cell receptor(high) thymocytes are resistant to peptide/major histocompatibility complex ligand-induced negative selection. Eur J Immunol 27(9):2279-89. [PubMed: 9341770] [MGI Ref ID J:133112]

Gubbels MR; Jorgensen TN; Metzger TE; Menze K; Steele H; Flannery SA; Rozzo SJ; Kotzin BL. 2005. Effects of MHC and gender on lupus-like autoimmunity in Nba2 congenic mice. J Immunol 175(9):6190-6. [PubMed: 16237116] [MGI Ref ID J:119371]

Klein J; Figueroa F; David CS. 1983. H-2 haplotypes, genes and antigens: second listing. II. The H-2 complex. Immunogenetics 17(6):553-96. [PubMed: 6407984] [MGI Ref ID J:7097]

Krupnick AS; Gelman AE; Barchet W; Richardson S; Kreisel FH; Turka LA; Colonna M; Patterson GA; Kreisel D. 2005. Murine vascular endothelium activates and induces the generation of allogeneic CD4+25+Foxp3+ regulatory T cells. J Immunol 175(10):6265-70. [PubMed: 16272276] [MGI Ref ID J:119348]

Laky K; Lewis JM; Tigelaar RE; Puddington L. 2003. Distinct requirements for IL-7 in development of TCR gamma delta cells during fetal and adult life. J Immunol 170(8):4087-94. [PubMed: 12682238] [MGI Ref ID J:125438]

Legge KL; Braciale TJ. 2005. Lymph node dendritic cells control CD8+ T cell responses through regulated FasL expression. Immunity 23(6):649-59. [PubMed: 16356862] [MGI Ref ID J:113311]

Mendiratta SK; Kovalik JP; Hong S; Singh N; Martin WD; Van Kaer L. 1999. Peptide dependency of alloreactive CD4+ T cell responses. Int Immunol 11(3):351-60. [PubMed: 10221647] [MGI Ref ID J:110542]

Miyashita N; Migita S; Moriwaki K. 1987. Effects of H-2 complex and non-H-2 background on urethane-induced chromosomal aberrations in mice. Mutat Res 176(1):59-67. [PubMed: 3099189] [MGI Ref ID J:109945]

Murphy DB. 1986. Overview: the murine MHC. In: Handbook of Experimental Immunology. Vol. 3, Genetic and Molecular Immunology. Blackwell Scientific Publ., Oxford. [MGI Ref ID J:30731]

Murphy WJ; Raziuddin A; Mason L; Kumar V; Bennett M; Longo DL. 1995. NK cell subsets in the regulation of murine hematopoiesis. I. 5E6+ NK cells promote hematopoietic growth in H-2d strain mice. J Immunol 155(6):2911-7. [PubMed: 7673708] [MGI Ref ID J:28582]

Oberg L; Johansson S; Michaelsson J; Tomasello E; Vivier E; Karre K; Hoglund P. 2004. Loss or mismatch of MHC class I is sufficient to trigger NK cell-mediated rejection of resting lymphocytes in vivo - role of KARAP/DAP12-dependent and -independent pathways. Eur J Immunol 34(6):1646-53. [PubMed: 15162434] [MGI Ref ID J:115484]

Porcellini S; Traggiai E; Schenk U; Ferrera D; Matteoli M; Lanzavecchia A; Michalak M; Grassi F. 2006. Regulation of peripheral T cell activation by calreticulin. J Exp Med 203(2):461-71. [PubMed: 16492806] [MGI Ref ID J:119147]

Poulin LF; Habran C; Stordeur P; Goldman M; McKenzie A; Van Snick J; Renauld JC; Braun MY. 2005. Interleukin-9 stimulates the production of interleukin-5 in CD4+ T cells. Eur Cytokine Netw 16(3):233-9. [PubMed: 16266865] [MGI Ref ID J:115764]

Reed-Loisel LM; Sullivan BA; Laur O; Jensen PE. 2005. An MHC class Ib-restricted TCR that cross-reacts with an MHC class Ia molecule. J Immunol 174(12):7746-52. [PubMed: 15944277] [MGI Ref ID J:109978]

Rodrigues OR; Moura RA; Gomes-Pereira S; Santos-Gomes GM. 2006. H-2 complex influences cytokine gene expression in Leishmania infantum-infected macrophages. Cell Immunol 243(2):118-26. [PubMed: 17316586] [MGI Ref ID J:120728]

Santiago ML; Montano M; Benitez R; Messer RJ; Yonemoto W; Chesebro B; Hasenkrug KJ; Greene WC. 2008. Apobec3 encodes Rfv3, a gene influencing neutralizing antibody control of retrovirus infection. Science 321(5894):1343-6. [PubMed: 18772436] [MGI Ref ID J:138778]

Sho M; Yamada A; Najafian N; Salama AD; Harada H; Sandner SE; Sanchez-Fueyo A; Zheng XX; Strom TB; Sayegh MH. 2002. Physiological mechanisms of regulating alloimmunity: cytokines, CTLA-4, CD25+ cells, and the alloreactive T cell clone size. J Immunol 169(7):3744-51. [PubMed: 12244168] [MGI Ref ID J:120408]

Sutton VR; Waterhouse NJ; Browne KA; Sedelies K; Ciccone A; Anthony D; Koskinen A; Mullbacher A; Trapani JA. 2007. Residual active granzyme B in cathepsin C-null lymphocytes is sufficient for perforin-dependent target cell apoptosis. J Cell Biol 176(4):425-33. [PubMed: 17283185] [MGI Ref ID J:119725]

Ueno T; Habicht A; Clarkson MR; Albin MJ; Yamaura K; Boenisch O; Popoola J; Wang Y; Yagita H; Akiba H; Ansari MJ; Yang J; Turka LA; Rothstein DM; Padera RF; Najafian N; Sayegh MH. 2008. The emerging role of T cell Ig mucin 1 in alloimmune responses in an experimental mouse transplant model. J Clin Invest 118(2):742-51. [PubMed: 18172549] [MGI Ref ID J:131045]

Varadhachary AS; Monestier M; Salgame P. 2001. Reciprocal induction of IL-10 and IL-12 from macrophages by low-density lipoprotein and its oxidized forms. Cell Immunol 213(1):45-51. [PubMed: 11747355] [MGI Ref ID J:115363]

Venkatesan P; Finch RG; Wakelin D. 1993. MHC haplotype influences primary Giardia muris infections in H-2 congenic strains of mice. Int J Parasitol 23(5):661-4. [PubMed: 8225770] [MGI Ref ID J:21687]

Wang L; Han R; Lee I; Hancock AS; Xiong G; Gunn MD; Hancock WW. 2005. Permanent survival of fully MHC-mismatched islet allografts by targeting a single chemokine receptor pathway. J Immunol 175(10):6311-8. [PubMed: 16272282] [MGI Ref ID J:119345]

Zhang ZX; Yang L; Young KJ; DuTemple B; Zhang L. 2000. Identification of a previously unknown antigen-specific regulatory T cell and its mechanism of suppression. Nat Med 6(7):782-9. [PubMed: 10888927] [MGI Ref ID J:118729]

Zhou P; Szot GL; Guo Z; Kim O; He G; Wang J; Grusby MJ; Newell KA; Thistlethwaite JR; Bluestone JA; Alegre ML. 2000. Role of STAT4 and STAT6 signaling in allograft rejection and CTLA4-Ig-mediated tolerance. J Immunol 165(10):5580-7. [PubMed: 11067913] [MGI Ref ID J:119580]

Zosky GR; Larcombe AN; White OJ; Burchell JT; von Garnier C; Holt PG; Turner DJ; Wikstrom ME; Sly PD; Stumbles PA. 2009. Airway hyperresponsiveness is associated with activated CD4+ T cells in the airways. Am J Physiol Lung Cell Mol Physiol 297(2):L373-9. [PubMed: 19482896] [MGI Ref ID J:151339]

Health & husbandry

Health & Colony Maintenance Information

Currently there no information available for this strain. This may be due to the supply level of this strain.

Purchasing information

Pricing, Supply Level & Notes, Controls, General Terms & Conditions

Pricing

Pricing for USA, Canada and Mexico shipping destinations

Price (US dollars $)

Cryorecovery Fee $1900.00

Animals Provided
At least two mice that carry the mutation (if it is a mutant strain) will be provided. Their genotypes may not reflect those discussed in the strain description. Please inquire for possible genotypes and see additional details below.

	Price (US dollars $)
Cryorecovery Fee	$1900.00

Additional Supply Details

Pricing for International shipping destinations

Price (US dollars $)

Cryorecovery Fee $2470.00

Animals Provided
At least two mice that carry the mutation (if it is a mutant strain) will be provided. Their genotypes may not reflect those discussed in the strain description. Please inquire for possible genotypes and see additional details below.

	Price (US dollars $)
Cryorecovery Fee	$2470.00

Additional Supply Details

Supply Details

Standard Supply	Cryopreserved. Ready for recovery. Please refer to pricing and supply notes for further information.
Supply Notes	Cryorecovery - Standard. We will fulfill your order by providing at least two pair of mice, at least one animal of each pair carrying the mutation of interest. The total number of animals provided, their gender and genotype will vary. Please inquire if larger numbers of animals with specific genotype and genders are needed. Animals typically ship between 13 and 16 weeks from the date of your order. If a second cryorecovery is needed in order to provide the minimum number of animals, animals will ship within 25 weeks. IMPORTANT NOTE: The genotypes of animals provided may not reflect the mating scheme utilized by The Jackson Laboratory prior to cryopreservation, or that discussed in the strain description. Please inquire about possible genotypes which will be recovered for this specific strain. The Jackson Laboratory cannot guarantee the reproductive success of mice shipped to your facility. If the mice are lost after the first three days (post-arrival) or do not produce progeny at your facility, a new order and fee will be necessary. *Cryorecovery to establish a Dedicated Supply for greater quantities of mice.* Mice recovered can be used to establish a dedicated colony to contractually supply you mice according to your requirements. Price by quotation. For more information on Dedicated Supply, please contact JAX^® Services, Tel: 1-800-422-6423 (from U.S.A., Canada or Puerto Rico only) or 1-207-288-5845 (from any location). Genomic DNA is available for this strain from the Mouse DNA Resource.

Standard Supply

Cryopreserved. Ready for recovery. Please refer to pricing and supply notes for further information.

Supply Notes

Cryorecovery - Standard.
We will fulfill your order by providing at least two pair of mice, at least one animal of each pair carrying the mutation of interest. The total number of animals provided, their gender and genotype will vary. Please inquire if larger numbers of animals with specific genotype and genders are needed. Animals typically ship between 13 and 16 weeks from the date of your order. If a second cryorecovery is needed in order to provide the minimum number of animals, animals will ship within 25 weeks. IMPORTANT NOTE: The genotypes of animals provided may not reflect the mating scheme utilized by The Jackson Laboratory prior to cryopreservation, or that discussed in the strain description. Please inquire about possible genotypes which will be recovered for this specific strain. The Jackson Laboratory cannot guarantee the reproductive success of mice shipped to your facility. If the mice are lost after the first three days (post-arrival) or do not produce progeny at your facility, a new order and fee will be necessary.
Cryorecovery to establish a Dedicated Supply for greater quantities of mice.
Mice recovered can be used to establish a dedicated colony to contractually supply you mice according to your requirements. Price by quotation. For more information on Dedicated Supply, please contact JAX^® Services, Tel: 1-800-422-6423 (from U.S.A., Canada or Puerto Rico only) or 1-207-288-5845 (from any location).
Genomic DNA is available for this strain from the Mouse DNA Resource.

Control Information

	Control
	000666 C57BL/10SnJ

Considerations for Choosing Controls
USA, Canada and Mexico - Control Pricing Information for Genetically Engineered Mutant Strains.
International - Control Pricing Information for Genetically Engineered Mutant Strains.

Payment Terms and Conditions

Terms are granted by individual review and stated on the customer invoice(s) and account statement. These transactions are payable in U.S. currency within the granted terms. Payment for services, products, shipping containers, and shipping costs that are rendered are expected within the payment terms indicated on the invoice or stated by contract. Invoices and account balances in arrears of stated terms may result in The Jackson Laboratory pursuing collection activities including but not limited to outside agencies and court filings.

See Terms of Use tab for General Terms and Conditions

The Jackson Laboratory's Genotype Promise

The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX^® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX^® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX^® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.

Ordering and Purchasing Information

Purchasing Information
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Contact Information
Orders & Technical Support
Tel: 1-800-422-6423 or 1-207-288-5845
Fax: 1-207-288-6150
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phone:	207-288-6470
fax:	207-288-6655

JAX^® Mice, Products & Services Conditions of Use

"MICE" means mouse strains, their progeny derived by inbreeding or crossbreeding, unmodified derivatives from mouse strains or their progeny supplied by The Jackson Laboratory ("JACKSON"). "PRODUCTS" means biological materials supplied by JACKSON, and their derivatives. "RECIPIENT" means each recipient of MICE, PRODUCTS, or services provided by JACKSON including each institution, its employees and other researchers under its control. MICE or PRODUCTS shall not be: (i) used for any purpose other than the internal research, (ii) sold or otherwise provided to any third party for any use, or (iii) provided to any agent or other third party to provide breeding or other services. Acceptance of MICE or PRODUCTS from JACKSON shall be deemed as agreement by RECIPIENT to these conditions, and departure from these conditions requires JACKSON's prior written authorization.

No Warranty

MICE, PRODUCTS AND SERVICES ARE PROVIDED “AS IS”. JACKSON EXTENDS NO WARRANTIES OF ANY KIND, EITHER EXPRESS, IMPLIED, OR STATUTORY, WITH RESPECT TO MICE, PRODUCTS OR SERVICES, INCLUDING ANY IMPLIED WARRANTY OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE, OR ANY WARRANTY OF NON-INFRINGEMENT OF ANY PATENT, TRADEMARK, OR OTHER INTELLECTUAL PROPERTY RIGHTS.

In case of dissatisfaction for a valid reason and claimed in writing by a purchaser within ninety (90) days of receipt of mice, products or services, JACKSON will, at its option, provide credit or replacement for the mice or product received or the services provided.

No Liability

In no event shall JACKSON, its trustees, directors, officers, employees, and affiliates be liable for any causes of action or damages, including any direct, indirect, special, or consequential damages, arising out of the provision of MICE, PRODUCTS or services, including economic damage or injury to property and lost profits, and including any damage arising from acts or negligence on the part of JACKSON, its agents or employees. In purchasing or receiving MICE, PRODUCTS or services from JACKSON, purchaser or recipient, or any party claiming by or through them, expressly releases and discharges JACKSON from all such causes of action or damages, and further agrees to defend and indemnify JACKSON from any costs or damages arising out of any third party claims.

MICE and PRODUCTS are to be used in a safe manner and in accordance with all applicable governmental rules and regulations.

The foregoing represents the General Terms and Conditions applicable to JACKSON’s MICE, PRODUCTS or services. In addition, special terms and conditions of sale of certain MICE, PRODUCTS or services may be set forth separately in JACKSON web pages, catalogs, price lists, contracts, and/or other documents, and these special terms and conditions shall also govern the sale of these MICE, PRODUCTS and services by JACKSON, and by its licensees and distributors.

Acceptance of delivery of MICE, PRODUCTS or services shall be deemed agreement to these terms and conditions. No purchase order or other document transmitted by purchaser or recipient that may modify the terms and conditions hereof, shall be in any way binding on JACKSON, and instead the terms and conditions set forth herein, including any special terms and conditions set forth separately, shall govern the sale of MICE, PRODUCTS or services by JACKSON.

005308	B10.Cg-H2^d Tg(TcraCl4,TcrbCl4)1Shrm/ShrmJ
005534	B10.Cg-H2^d Tg(Ins2-HA)165Bri/ShrmJ
005895	B10.Cg-Thy1^a H2^d Tg(TcraCl1,TcrbCl1)1Shrm/J
000460	B10.D2-Hc⁰ H2^d H2-T18^c/o2SnJ
000461	B10.D2-Hc⁰ H2^d H2-T18^c/oSnJ
000463	B10.D2-Hc¹ H2^d H2-T18^c/nSnJ
003147	B10.D2-Hc¹ H2^d H2-T18^c/nSnJ-Tg(DO11.10)10Dlo/J
000360	B6.C-H2^d Mdmg1^BALB/cBy/aByJ
000359	B6.C-H2^d/bByJ
001893	BRVR.D2-H2^d/J
000437	D1.C-H2^d H2-T18^c/SnJ
003153	WLC.C-H2^d.GR-Mtv2/MorJ
003154	WLC.C-H2^d/MorJ

006500	129.NOD-(D17Mit175-H2)/J
001649	A.BY H2^bc H2-T18^f/SnJ-Dstn^corn1/J
000140	A.BY-H2^bc H2-T18^f/SnJ
000472	A.CA-H2^f H2-T18^a/SnJ
000471	A.SW-H2^s H2-T18^b/SnJ
001066	A.TH-H2^t2/SfDvEgMobJ
001067	A.TL-H2^t1/SfDvEgMobJ
002089	AK.B6-H2^b Fv1^b/J
002090	AK.B6-H2^b/J
001094	AK.L-H2^b/1CyTyJ
001095	AK.L-H2^oz2/CyJ
001096	AK.L-H2^oz3/CyJ
000470	AK.M-H2^m H2-T18^a/nSnJ
003851	ALR.NOD-(D17Mit30-D17Mit123)/Lt
000469	B10.A-H2^a H2-T18^a/SgSnJ
000468	B10.A-H2^h2/(2R)SgSnJ
001150	B10.A-H2^h4/(4R)SgDvEgJ
001149	B10.A-H2ⁱ³/(3R)SgDvEgJ
000467	B10.A-H2ⁱ⁵ H2-T18^a/(5R)SgSnJ
000466	B10.AKM-H2^m H2-T18^a/SnJ
001954	B10.AQR-H2^y1/KljMcdJ
000465	B10.BR-H2^k H2-T18^a/SgSnJ
004804	B10.BR-H2^k H2-T18^a/SgSnJJrep
006446	B10.Cg H2^h4-Sh3pxd2b^nee/GrsrJ
010514	B10.Cg-H2^g Tg(Cd4-Klra1)6295Dl/J
006100	B10.Cg-H2^k Tg(NFkB/Fos-luc)26Rinc/J
006102	B10.Cg-H2^k Tg(Il2/NFAT-luc)83Rinc/J
002024	B10.D1-H2^q/SgJ
001163	B10.D2-H2^bm23/EgJ
001164	B10.D2-H2^dm1/EgJ
001151	B10.D2-H2^g3/(103R)EgJ
001153	B10.D2-H2ⁱ⁷/(107R)EgJ
001152	B10.D2-H2^ia/(106R)EgJ
000464	B10.DA-H2^qp1 H2-T18^b/(80NS)SnJ
001823	B10.F-H2^bp5/(14R)J
001818	B10.F-H2^pb1/(13R)J
001012	B10.HTG-H2^g/2CyJ
000999	B10.HTG-H2^g/3CyJ
001894	B10.LG-H2^ar1/J
000459	B10.M-H2^f H2-T18^a^?/SnJ
002225	B10.M-H2^f/nMob Fmn1^ld-2J/J
001068	B10.M-H2^f/nMobJ
000739	B10.M-H2^fm2/MobJ
001154	B10.MBR-H2^bq1/SxEgJ
010972	B10.NOD-(rs13459152-rs13483054)/1107MrkJ
001825	B10.P-H2^kp1/(10R)SgJ
003199	B10.PL-H2^u H2-T18^a/(73NS)Sn-Tg(TCRA)B1Jg/J
003200	B10.PL-H2^u H2-T18^a/(73NS)Sn-Tg(TCRB)C14Jg/J
000458	B10.PL-H2^u H2-T18^a/(73NS)SnJ
003599	B10.RIII H2^r H2-T18^b/(71NS)Sn-Ap3b1^pe-11J/J
000457	B10.RIII-H2^r H2-T18^b/(71NS)SnJ
001069	B10.RIII-H2^r/(71NS)nMobJ
001760	B10.S-H2^as1/(8R)/J
001953	B10.S-H2^s/SgMcdJ
001817	B10.S-H2^sm1/(12R)SgJ
001650	B10.S-H2^t4/(9R)/J
000456	B10.SM H2^v H2-T18^b/(70NS)Sn-cw/J
001155	B10.T-H2^y2/(6R)SgDvEgJ
000445	B10.WB-H2^j H2-T18^b/SnJ
000444	B10.Y-H2^pa H2-T18^c/SnJ
003483	B6 x B10.D1-H2^q/SgJ-Nox3^het-2J/J
003561	B6 x B10.PL-H2^u/(73NS)Sn-Hxl/J
002995	B6 x C.B10-H2^b/LiMcdJ-Fbn2^fp-2J/J
005717	B6(NOD) H2^g7-Sostdc1^shk/J
003584	B6.129S2-H2^dlAb1-Ea/J
001148	B6.AK-H2^k/FlaEgJ
001895	B6.AK-H2^k/J
001160	B6.C-H2^bm10/KhEgJ
001161	B6.C-H2^bm11/KhEgJ
000364	B6.C-H2^bm2/ByJ
000369	B6.C-H2^bm4/ByJ
001158	B6.C-H2^bm7/KhEgJ
001429	B6.C-H2^g6/J
005715	B6.Cg H2^g7-Tg(Ins2-CD80)3B7Flv/LwnJ
007958	B6.Cg-H2^b3/FlaCmwJ
007959	B6.Cg-H2^b4/FlaCmwJ
003068	B6.NOD-(Csf2-D11Mit42) (D17Mit21-D17Mit10)/J
003300	B6.NOD-(D17Mit21-D17Mit10)/LtJ
003069	B6.NOD-(D1Mit3-Bcl2) (D17Mit21-D17Mit10)/LtJ
003071	B6.NOD-(D1Mit5.1-D1Mit15) (D17Mit21-D17Mit10)/J
003067	B6.NOD-(D3Mit132-Tshb) (D17Mit21-D17Mit10)/J
003066	B6.NOD-(D6Mit54-D6Mit14) (D17Mit21-D17Mit10)/J
000944	B6.SJL-H2^b C3^c/2CyJ
000966	B6.SJL-H2^s C3^c/1CyJ
000945	B6.SW/1CyJ
003374	B6;129S2-H2^dlAb1-Ea/J
003240	B6;B10.A-H2^a-Tg(H2KmPCC)2939Stoe/J
002844	BALB.5R-H2ⁱ⁵/LilJ
001165	BALB/c-H2^dm2/KhEgJ
001041	BKS.B6-H2^b/J
001892	BRVR.B10-H2^b/J
002845	C.B-H2^b Tg(H2-D^d)D8Gja/LilJ
001952	C.B10-H2^b/LilMcdJ
001951	C.C3-H2^k/LilMcdJ
000443	C3.HTG-H2^g H2-T18^b^?/SnJ
000441	C3.JK-H2^j H2-T18^b/SnJ
000440	C3.LG-H2^ar1/CkcCyJ
000439	C3.NB-H2^p H2-T18^c^?/SnJ
000438	C3.SW-H2^b/SnJ
000473	C3H-H2^o2 C4b^b/SfSnJ
001156	C57BL/6J-H2^bm3/EgJ
001157	C57BL/6Kh-H2^bm5/KhEgJ
000436	D1.DA-H2^qp1/SnJ
000435	D1.LP-H2^b H2-T18^b^?/SnJ
000434	LP.RIII-H2^r H2-T18^b/SnJ
001383	LT.MA-Glo1^b H2^k/J
002591	NOD.B10Sn-H2^b/J
006935	NOD.Cg-H2^b thnh/J
004447	NOD.Cg-H2^h4/DilTacUmmJ
001626	NOD.NON-H2^nb1/LtJ
002032	NOD.SW-H2^q/J
001627	NON.NOD-H2^g7/LtJ
002974	STOCK Es1^e H2^d/J
001308	STOCK H2^473a/J

Strain Name:

B10.D2-H2d/n2SnJ

Stock Number:

000462

Availability:

Cryopreserved - Ready for recovery

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JAX® Mice, Products & Services Conditions of Use

No Warranty

No Liability

B10.D2-H2^d/n2SnJ

JAX^® Mice, Products & Services Conditions of Use