Strain Name: |
B10.D2-Hc1 H2d H2-T18c/nSnJ |
|---|---|
Stock Number: |
000463 |
Availability: | Level 2 |
Price and Supply Information | |
General Terms and Conditions |
| Genes & Alleles | H2-T18; H2; H2d; Hc; Hc1; ; |
Product Information
Strain Details
Type JAX® GEMM® Strain - Congenic Additional information on JAX® GEMM® Strains. Type JAX® GEMM® Strain - Major Histocompatibility Congenic Type JAX® GEMM® Strain - Mutant Strain Mating System Homozygote x Homozygote (Female x Male) Species laboratory mouse Background Strain C57BL/10Sn Donor Strain DBA/2 Generation N16F105 (03-JAN-08) Appearance
black
Related Genotype: a/a
Gene & Allele Details
| Allele Symbol | H2d | ||
|---|---|---|---|
| Allele Name | d variant | ||
| Gene Symbol and Name | H2, histocompatibility-2, MHC | ||
| Chromosome | 17 | ||
| Gene Common Name(s) | H-2; MHC-II; | ||
| General Note | The d variant has been observed in the following strains: DBA/2, DBA/2J BALB/c, BALB/cByJ, BALB/cJ, C57BLKS, NZB | ||
| Allele Symbol | Hc1 | ||
| Allele Name | sufficient | ||
| Common Name(s) | C5 sufficient; C5-s; C5-suf; | ||
| Gene Symbol and Name | Hc, hemolytic complement | ||
| Chromosome | 2 | ||
| Gene Common Name(s) | C5; C5a; CPAMD4; FLJ17816; FLJ17822; He; MGC142298; RGD1561905; | ||
| General Note |
Hc was identified as a candidate gene for Abhr2 in a microarray analysis of lung mRNA from A/J, C3H/HeJ, and (A/J x C3H/HeJ)F1 x A/J backcross animals. Hc genotype shows statistically significant correlation to allergen-induced bronchial hyperresponsive phenotype. The C3H/HeJ allele does not have the 2 bp deletion and is associated with resistance to allergen-induced bronchial hyperresponsiveness. (J:108211) | ||
| Molecular Note | This allele does not contain the 2 base "TA" deletion found in the Hc0 allele and is found in the following mouse strains BALB/cJ, C57BL/6J, DBA/1J, and B10.D2/nSnJ. This is equivalent to the wild-type allele. [MGI Ref ID J:23983] | ||
| Gene Symbol and Name | H2-T18, histocompatibility 2, T region locus 18 | ||
| Chromosome | 17 | ||
| Gene Common Name(s) | H-2T18; TL Ag; Tla; thymus leukemia antigen; | ||
Control Information
| Control | ||
|---|---|---|
| 000666 C57BL/10SnJ | ||
| Considerations for Choosing Controls | ||
| Control Pricing Information for JAX® GEMM® Strains | ||
Colony Maintenance
| Diet Information | LabDiet® 5K52/5K67 |
|---|
Related Strains
Strains carrying H2d allele
005308 B10.Cg-H2d Tg(TcraCl4,TcrbCl4)1Shrm/ShrmJ 005534 B10.Cg-H2d Tg(Ins2-HA)165Bri/ShrmJ 005895 B10.Cg-Thy1a H2d Tg(TcraCl1,TcrbCl1)1Shrm/J 000462 B10.D2-H2d/n2SnJ 000460 B10.D2-Hc0 H2d H2-T18c/o2SnJ 000461 B10.D2-Hc0 H2d H2-T18c/oSnJ 003147 B10.D2-Hc1 H2d H2-T18c/nSnJ-Tg(DO11.10)10Dlo/J 000360 B6.C-H2d Mdmg1BALB/cBy/aByJ 000359 B6.C-H2d/bByJ 001893 BRVR.D2-H2d/J 000437 D1.C-H2d H2-T18c/SnJ 003153 WLC.C-H2d.GR-Mtv2/MorJ 003154 WLC.C-H2d/MorJ View Strains carrying H2d (13 strains)
000470 AK.M-H2m H2-T18a/nSnJ 005308 B10.Cg-H2d Tg(TcraCl4,TcrbCl4)1Shrm/ShrmJ 003147 B10.D2-Hc1 H2d H2-T18c/nSnJ-Tg(DO11.10)10Dlo/J 004306 NOD.CBALs-Hc1/LtJ
Phenotypic Data
Mouse Phenome Database
Additional Web Information
Congenic Nomenclature
Genetic Quality Control Annual Report
JAX® NOTES, October 1989; 439. Splenic Melanosis in Black Mice.
Animal Health Reports
Room Number MP13
Research Applications
This mouse can be used to support research in many areas including:
H2d relatedImmunology and Inflammation Research
CD Antigens, Antigen Receptors, and Histocompatibility Markers
Hc1 relatedImmunology and Inflammation Research
CD Antigens, Antigen Receptors, and Histocompatibility Markers
Immunodeficiency (specific complement deficiency) (control)
Research Tools
Immunology and Inflammation Research (specific complement deficiency) (C5 complement) (control)
References
Additional ReferencesPrice and Supply Information
| Strain Name: | B10.D2-Hc1 H2d H2-T18c/nSnJ |
| Stock Number: | 000463 |
Price Details
IMPORTANT NOTE: Prices are based on shipping destination. The shipping destinations are:
- USA, Canada and Mexico
- International
*Pricing for Shipping Destination selected:
International
| Price(s) in US dollars ($) | Genotype(s) Provided | ||||
|---|---|---|---|---|---|
| 3-5 weeks | $58.50 | Homozygous for Hc1, Homozygous for H2d, Homozygous for H2-T18c | Female | ||
| 6 weeks | $61.00 | Homozygous for Hc1, Homozygous for H2d, Homozygous for H2-T18c | Female | ||
| 7 weeks | $63.50 | Homozygous for Hc1, Homozygous for H2d, Homozygous for H2-T18c | Female | ||
| 8 weeks | $66.00 | Homozygous for Hc1, Homozygous for H2d, Homozygous for H2-T18c | Female | ||
| 9 weeks | $68.50 | Homozygous for Hc1, Homozygous for H2d, Homozygous for H2-T18c | Female | ||
| 10 weeks | $71.00 | Homozygous for Hc1, Homozygous for H2d, Homozygous for H2-T18c | Female | ||
| 3-5 weeks | $49.80 | Homozygous for Hc1, Homozygous for H2d, Homozygous for H2-T18c | Male | ||
| 6 weeks | $52.30 | Homozygous for Hc1, Homozygous for H2d, Homozygous for H2-T18c | Male | ||
| 7 weeks | $54.80 | Homozygous for Hc1, Homozygous for H2d, Homozygous for H2-T18c | Male | ||
| 8 weeks | $57.30 | Homozygous for Hc1, Homozygous for H2d, Homozygous for H2-T18c | Male | ||
| 9 weeks | $59.80 | Homozygous for Hc1, Homozygous for H2d, Homozygous for H2-T18c | Male | ||
| 10 weeks | $62.30 | Homozygous for Hc1, Homozygous for H2d, Homozygous for H2-T18c | Male | ||
Supply Details
| Standard Supply | Level 2. Up to 100 mice. Larger quantities or custom orders arranged upon request. |
|---|---|
| Supply Notes |
Histology and Tissue Collection Services are available for all JAX® Mice strains. For more information, please contact Customer Service at orderquest@jax.org or 1-207-288-5845. Shipped at a specific age in weeks. Mice at a precise age in days, littermates and retired breeders are also available. Strains that must be genotyped are not available until five to seven weeks of age. Genomic DNA is available for this strain from the Mouse DNA Resource. |
| Licensing | See General Terms and Conditions below |
| Control Information | View Control Information in Strain Details. View Control Pricing Information for JAX® Strains. |
General Terms and Conditions
View JAX® Mice & Services Conditions of Use.
The Jackson Laboratory's Genotype Promise
The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.Ordering and Purchasing Information
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Contact Information
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Tel: 800.422.6423 or 207.288.5845
Fax: 207.288.6150
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