Strain Name: |
B10.BR-H2k H2-T18a/SgSnJ |
|---|---|
Stock Number: |
000465 |
Availability: | Level 2 |
Price and Supply Information | |
General Terms and Conditions |
| Genes & Alleles | H2-T18; H2; H2k; ; |
Product Information
Strain Details
Type JAX® GEMM® Strain - Congenic Additional information on JAX® GEMM® Strains. Type JAX® GEMM® Strain - Major Histocompatibility Congenic Type JAX® GEMM® Strain - Mutant Strain Mating System Sibling x Sibling (Female x Male) Species laboratory mouse Background Strain C57BL/10SnSg Donor Strain C57BR/cdJ Generation N9F102 (14-DEC-06) Appearance
black, may exhibit white belly spots
Related Genotype: a/aStrain Description
Some phenotypic parameters of the B10.BR-H2k H2-T18a/SgSnJ mice may have changed recently relative to the strain's previous performance. In order to confirm that a change had occurred and in order to better characterize any differences that may have arisen, animals were recovered from cryo-preserved embryos of the strain (Stock No. 004804) that had been frozen in 1991, and the two lines of B10.BR-H2k H2-T18a/SgSnJ were compared. Differences between the two strains have been identified in the CD4/CD8 ratios among several cell populations, and in some dendritic cell populations. As more information is gathered, this website will be updated. Both colonies of B10.BR-H2k H2-T18a/SgSnJ (Stock No's. 000465 and 004804) may exhibit white belly spots; these spots are considered a strain characteristic.
Gene & Allele Details
| Allele Symbol | H2k | ||
|---|---|---|---|
| Allele Name | k variant | ||
| Common Name(s) | H-2k; | ||
| Gene Symbol and Name | H2, histocompatibility-2, MHC | ||
| Chromosome | 17 | ||
| Gene Common Name(s) | H-2; MHC-II; | ||
| General Note | The k variant has been observed in the following strains: C3H, C3H/HeJ, C3H/An, C3H/Bi, C3H/DiSn, C3H/St, CBA, CBA/CaJ, CBA/N, AKR/J, CE/J, C57BR/cdJ, C58/J, MA/J, RF/J, ST/bJ, MRL/MpJ-Faslpr/J | ||
| Gene Symbol and Name | H2-T18, histocompatibility 2, T region locus 18 | ||
| Chromosome | 17 | ||
| Gene Common Name(s) | H-2T18; TL Ag; Tla; thymus leukemia antigen; | ||
Control Information
| Control | ||
|---|---|---|
| 000666 C57BL/10SnJ | (approximate) | |
| Considerations for Choosing Controls | ||
| Control Pricing Information for JAX® GEMM® Strains | ||
Colony Maintenance
| Diet Information | LabDiet® 5K52/5K67 |
|---|
Related Strains
Strains carrying H2k allele
004804 B10.BR-H2k H2-T18a/SgSnJJrep 006102 B10.Cg-H2k Tg(Il2/NFAT-luc)83Rinc/J 006100 B10.Cg-H2k Tg(NFkB/Fos-luc)26Rinc/J 001148 B6.AK-H2k/FlaEgJ 001895 B6.AK-H2k/J 001951 C.C3-H2k/LilMcdJ 001383 LT.MA-Glo1b H2k/J View Strains carrying H2k (7 strains)
Additional Web Information
Congenic Nomenclature
Genetic Quality Control Annual Report
JAX Notes, October 1989; 439. Splenic Melanosis in Black Mice.
Level B Pathogen, November /December 2003
Animal Health Reports
Room Number MP13
Research Applications
This mouse can be used to support research in many areas including:
H2k relatedImmunology and Inflammation Research
CD Antigens, Antigen Receptors, and Histocompatibility Markers
Immunology and Inflammation Research
CD Antigens, Antigen Receptors, and Histocompatibility Markers
References
Additional ReferencesPrice and Supply Information
| Strain Name: | B10.BR-H2k H2-T18a/SgSnJ |
| Stock Number: | 000465 |
Price Details
IMPORTANT NOTE: Prices are based on shipping destination. The shipping destinations are:
- USA, Canada and Mexico
- International
*Pricing for Shipping Destination selected:
International
| Price(s) in US dollars ($) | Genotype(s) Provided | ||||
|---|---|---|---|---|---|
| 3-5 weeks | $45.30 | Homozygous for H2k, Homozygous for H2-T18a | Female | ||
| 6 weeks | $47.80 | Homozygous for H2k, Homozygous for H2-T18a | Female | ||
| 7 weeks | $50.30 | Homozygous for H2k, Homozygous for H2-T18a | Female | ||
| 8 weeks | $52.80 | Homozygous for H2k, Homozygous for H2-T18a | Female | ||
| 3-5 weeks | $45.30 | Homozygous for H2k, Homozygous for H2-T18a | Male | ||
| 6 weeks | $47.80 | Homozygous for H2k, Homozygous for H2-T18a | Male | ||
| 7 weeks | $50.30 | Homozygous for H2k, Homozygous for H2-T18a | Male | ||
| 8 weeks | $52.80 | Homozygous for H2k, Homozygous for H2-T18a | Male | ||
Supply Details
| Standard Supply | Level 2. Up to 100 mice. Larger quantities or custom orders arranged upon request. |
|---|---|
| Supply Notes |
Histology and Tissue Collection Services are available for all JAX® Mice strains. For more information, please contact Customer Service at orderquest@jax.org or 1-207-288-5845. Shipped at a specific age in weeks. Mice at a precise age in days, littermates and retired breeders are also available. Strains that must be genotyped are not available until five to seven weeks of age. Genomic DNA is available for this strain from the Mouse DNA Resource. |
| Licensing | See General Terms and Conditions below |
| Control Information | View Control Information in Strain Details. View Control Pricing Information for JAX® Strains. |
General Terms and Conditions
View JAX® Mice & Services Conditions of Use.
The Jackson Laboratory's Genotype Promise
The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.Ordering and Purchasing Information
Purchasing Information
JAX® Mice Orders
Surgical Services
Contact Information
Orders & Technical Support
Tel: 800.422.6423 or 207.288.5845
Fax: 207.288.6150
Technical Support Email Form