JAX Mice Database - 000468 B10.A-H2<h2>/(2R)SgSnJ

Strain Name:	B10.A-H2^h2/(2R)SgSnJ
Stock Number:	000468
Availability:	Repository- Live

Description
Phenotype
Genes & alleles
Genotyping
Health & husbandry
References
Purchasing information
Terms of Use

Description

Strain Information

Former Names B10.A-H2^h2 (2R)/SgSnJ (Changed: 15-DEC-04 )

B10.A-H2^h2/(2R)SgSnJ (Changed: 15-DEC-04 )

Type Congenic; Major Histocompatibility Congenic; Mutant Strain;
Additional information on Genetically Engineered Mutant Mice.

Mating System Sibling x Sibling (Female x Male)

Species laboratory mouse

Background Strain C57BL/10SnSg

Donor Strain A/WySn

Generation N10F141+3 (26-DEC-07)

Appearance
black
Related Genotype: a/a

Control Information

	Control
	000666 C57BL/10SnJ	(approximate)

Considerations for Choosing Controls

Related Strains

Strains carrying other alleles of H2

000471 A.SW-H2^s H2-T18^b/SnJ

002089 AK.B6-H2^b Fv1^b/J

002090 AK.B6-H2^b/J

001094 AK.L-H2^b/1CyTyJ

003851 ALR.NOD-(D17Mit30-D17Mit123)/Lt

000469 B10.A-H2^a H2-T18^a/SgSnJ

001150 B10.A-H2^h4/(4R)SgDvEgJ

000467 B10.A-H2ⁱ⁵ H2-T18^a/(5R)SgSnJ

000465 B10.BR-H2^k H2-T18^a/SgSnJ

004804 B10.BR-H2^k H2-T18^a/SgSnJJrep

005308 B10.Cg-H2^d Tg(TcraCl4,TcrbCl4)1Shrm/ShrmJ

005534 B10.Cg-H2^d Tg(Ins2-HA)165Bri/ShrmJ

006102 B10.Cg-H2^k Tg(Il2/NFAT-luc)83Rinc/J

006100 B10.Cg-H2^k Tg(NFkB/Fos-luc)26Rinc/J

005895 B10.Cg-Thy1^a H2^d Tg(TcraCl1,TcrbCl1)1Shrm/J

002024 B10.D1-H2^q/SgJ

000462 B10.D2-H2^d/n2SnJ

001153 B10.D2-H2ⁱ⁷/(107R)EgJ

000460 B10.D2-Hc⁰ H2^d H2-T18^c/o2SnJ

000461 B10.D2-Hc⁰ H2^d H2-T18^c/oSnJ

000463 B10.D2-Hc¹ H2^d H2-T18^c/nSnJ

003147 B10.D2-Hc¹ H2^d H2-T18^c/nSnJ-Tg(DO11.10)10Dlo/J

001953 B10.S-H2^s/SgMcdJ

002995 B6 x C.B10-H2^b/LiMcdJ-Fbn2^fp-2J/J

005717 B6(NOD) H2^g7-Sostdc1^shk/J

003584 B6.129S2-H2^dlAb1-Ea/J

001148 B6.AK-H2^k/FlaEgJ

001895 B6.AK-H2^k/J

000360 B6.C-H2^d Mdmg1^BALB/cBy/aByJ

000359 B6.C-H2^d/bByJ

005715 B6.Cg H2^g7-Tg(Ins2-CD80)3B7Flv/LwnJ

003068 B6.NOD-(Csf2-D11Mit42) (D17Mit21-D17Mit10)/J

003300 B6.NOD-(D17Mit21-D17Mit10)/LtJ

003069 B6.NOD-(D1Mit3-Bcl2) (D17Mit21-D17Mit10)/LtJ

003071 B6.NOD-(D1Mit5.1-D1Mit15) (D17Mit21-D17Mit10)/J

003067 B6.NOD-(D3Mit132-Tshb) (D17Mit21-D17Mit10)/J

003066 B6.NOD-(D6Mit54-D6Mit14) (D17Mit21-D17Mit10)/J

000944 B6.SJL-H2^b C3^c/2CyJ

000966 B6.SJL-H2^s C3^c/1CyJ

000945 B6.SW/1CyJ

003374 B6;129S2-H2^dlAb1-Ea/J

003240 B6;B10.A-H2^a-Tg(H2KmPCC)2939Stoe/J

002844 BALB.5R-H2ⁱ⁵/LilJ

001041 BKS.B6-H2^b/J

001892 BRVR.B10-H2^b/J

001893 BRVR.D2-H2^d/J

001952 C.B10-H2^b/LilMcdJ

001951 C.C3-H2^k/LilMcdJ

000438 C3.SW-H2^b/SnJ

000437 D1.C-H2^d H2-T18^c/SnJ

000435 D1.LP-H2^b H2-T18^b^?/SnJ

001383 LT.MA-Glo1^b H2^k/J

002591 NOD.B10Sn-H2^b/J

004447 NOD.Cg-H2^h4/DilTacUmmJ

002032 NOD.SW-H2^q/J

001627 NON.NOD-H2^g7/LtJ

003153 WLC.C-H2^d.GR-Mtv2/MorJ

003154 WLC.C-H2^d/MorJ

View Strains carrying other alleles of H2 (58 strains)

Additional Web Information

Congenic Nomenclature
Genetic Quality Control Annual Report
JAX^® NOTES, October 1989; 439. Splenic Melanosis in Black Mice.

Phenotype

Phenotype Information

View Research Applications

Research Applications
This mouse can be used to support research in many areas including:

Immunology and Inflammation Research
CD Antigens, Antigen Receptors, and Histocompatibility Markers

Genes & Alleles

Gene & Allele Information

Allele Symbol		H2^h2
Allele Name		h2 variant
Allele Type		Not Applicable
Gene Symbol and Name		H2, histocompatibility-2, MHC
Chromosome		17
Gene Common Name(s)		H-2; MHC-II;
General Note		The h2 variant has been observed in the following strains: B10.A(2R)/SgSn

Genotyping

Genotyping Information

This strain will not have a genotyping protocol or one is not currently available.

Helpful Links

Optimizing PCR Protocols

References

Additional References

H2^h2 related

Miyashita N; Migita S; Moriwaki K. 1987. Effects of H-2 complex and non-H-2 background on urethane-induced chromosomal aberrations in mice. Mutat Res 176(1):59-67. [PubMed: 3099189] [MGI Ref ID J:109945]

Moons L; Shi C; Ploplis V; Plow E; Haber E; Collen D; Carmeliet P. 1998. Reduced transplant arteriosclerosis in plasminogen-deficient mice. J Clin Invest 102(10):1788-97. [PubMed: 9819364] [MGI Ref ID J:115027]

Podolin PL; Pressey A; DeLarato NH; Fischer PA; Peterson LB; Wicker LS. 1993. I-E+ nonobese diabetic mice develop insulitis and diabetes. J Exp Med 178(3):793-803. [PubMed: 8350054] [MGI Ref ID J:14178]

Reed-Loisel LM; Sullivan BA; Laur O; Jensen PE. 2005. An MHC class Ib-restricted TCR that cross-reacts with an MHC class Ia molecule. J Immunol 174(12):7746-52. [PubMed: 15944277] [MGI Ref ID J:109978]

Health & husbandry

Health & Colony Maintenance Information

Animal Health Reports
Room Number AX11

Colony Maintenance

Mating System Sibling x Sibling (Female x Male)

Diet Information LabDiet® 5K52/5K67

Mating System	Sibling x Sibling (Female x Male)
Diet Information	LabDiet® 5K52/5K67

Weeks of Age	Price*	Gender	Genotypes Provided
Individual Mouse Price	$41.50	Female or Male	Homozygous for H2^h2

Supply Notes	Histology and Tissue Collection Services are available for all JAX^® Mice strains. For more information, please contact Customer Service at orderquest@jax.org or 1-800-422-6423.

Weeks of Age	Price*	Gender	Genotypes Provided
Individual Mouse Price	$54.00	Female or Male	Homozygous for H2^h2

Supply Notes	Histology and Tissue Collection Services are available for all JAX^® Mice strains. For more information, please contact Customer Service at orderquest@jax.org or 1-207-288-5845.

Standard Supply	Repository-Live. A collection of over 1000 strains maintained as live colonies. Individual colonies are sized to meet current customer demand. Delivery for orders of 10 mice or less ranges on average from one to eight weeks; mice are generally shipped between four to six weeks of age with a maximum shipping age of ~nine weeks. Colony sizes do not generally support stringent age specifications for large volumes of mice; however custom orders and larger quantities of mice are easily arranged. Estimated ship dates for all orders provided within 48 hours of order placement.
Supply Notes	Usually shipped between four and eight weeks of age. This strain is included in the Mouse Mutant Resource collection. Genomic DNA is available for this strain from the Mouse DNA Resource.

Repository-Live. A collection of over 1000 strains maintained as live colonies. Individual colonies are sized to meet current customer demand. Delivery for orders of 10 mice or less ranges on average from one to eight weeks; mice are generally shipped between four to six weeks of age with a maximum shipping age of ~nine weeks. Colony sizes do not generally support stringent age specifications for large volumes of mice; however custom orders and larger quantities of mice are easily arranged. Estimated ship dates for all orders provided within 48 hours of order placement.

Supply Notes

Usually shipped between four and eight weeks of age.
This strain is included in the Mouse Mutant Resource collection.
Genomic DNA is available for this strain from the Mouse DNA Resource.

Control Information

	Control
	000666 C57BL/10SnJ	(approximate)

Considerations for Choosing Controls
USA, Canada and Mexico - Control Pricing Information for Genetically Engineered Mutant Strains.
International - Control Pricing Information for Genetically Engineered Mutant Strains.

General Terms and Conditions

See Terms of Use

The Jackson Laboratory's Genotype Promise

The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX^® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX^® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX^® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.

Ordering and Purchasing Information

Purchasing Information
JAX^® Mice Orders
Surgical Services

Contact Information
Orders & Technical Support
Tel: 800.422.6423 or 207.288.5845
Fax: 207.288.6150
Technical Support Email Form

Terms of Use

General Terms and Conditions

Contact information

General inquiries

Contracts Administration

phone:	207-288-6470
fax:	207-288-6655

JAX^® Mice & Services Conditions of Use

“Each recipient institution, including its employees and other researchers under its control (RECIPIENT), of mice or services using mice from The Jackson Laboratory (TJL) agrees that such mice, descendants of those mice derived by inbreeding or crossbreeding, including unmodified derivatives of those mice or their descendants (“MICE”) shall not be: (i) used for any purpose other than the internal research of the RECIPIENT, (ii) sold or otherwise provided to any third party for any use, or (iii) provided to any agent or other third party to provide breeding or other services with respect to MICE. Acceptance of MICE from TJL shall be deemed agreement by RECIPIENT to these conditions, and departure from these conditions requires The Jackson Laboratory’s prior written authorization.”

No Warranty

MICE, PRODUCTS AND SERVICES ARE PROVIDED “AS IS”. THE LABORATORY EXTENDS NO WARRANTIES OF ANY KIND, EITHER EXPRESS, IMPLIED, OR STATUTORY, WITH RESPECT TO MICE, PRODUCTS OR SERVICES, INCLUDING ANY IMPLIED WARRANTY OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE, OR ANY WARRANTY OF NON-INFRINGEMENT OF ANY PATENT, TRADEMARK, OR OTHER INTELLECTUAL PROPERTY RIGHTS.

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No Liability

In no event shall The Jackson Laboratory, its trustees, directors, officers, employees, and affiliates be liable for any causes of action or damages, including any direct, indirect, special, or consequential damages, arising out of the provision of MICE, products or services, including economic damage or injury to property and lost profits, and including any damage arising from acts or negligence on the part of The Jackson Laboratory, its agents or employees. In purchasing or receiving MICE, products or services from The Jackson Laboratory, purchaser or recipient, or any party claiming by or through them, expressly releases and discharges The Jackson Laboratory from all such causes of action or damages, and further agrees to defend and indemnify The Jackson Laboratory from any costs or damages arising out of any third party claims.

MICE and biological materials are to be used in a safe manner and in accordance with all applicable governmental rules and regulations.

The foregoing represents the General Terms and Conditions applicable to The Jackson Laboratory’s MICE, products and services. In addition, special terms and conditions of sale of certain MICE, products and services may be set forth separately in The Jackson Laboratory web pages, catalogs, price lists, contracts, and/or other documents, and these special terms and conditions shall also govern the sale of these MICE, products and services by The Jackson Laboratory, and by its licensees and distributors.

Acceptance of delivery of MICE, products or services shall be deemed agreement to these terms and conditions. No purchase order or other document transmitted by purchaser or recipient that may modify the terms and conditions hereof, shall be in any way binding on The Jackson Laboratory, and instead the terms and conditions set forth herein, including any special terms and conditions set forth separately, shall govern the sale of MICE, products services by The Jackson Laboratory.

000471	A.SW-H2^s H2-T18^b/SnJ
002089	AK.B6-H2^b Fv1^b/J
002090	AK.B6-H2^b/J
001094	AK.L-H2^b/1CyTyJ
003851	ALR.NOD-(D17Mit30-D17Mit123)/Lt
000469	B10.A-H2^a H2-T18^a/SgSnJ
001150	B10.A-H2^h4/(4R)SgDvEgJ
000467	B10.A-H2ⁱ⁵ H2-T18^a/(5R)SgSnJ
000465	B10.BR-H2^k H2-T18^a/SgSnJ
004804	B10.BR-H2^k H2-T18^a/SgSnJJrep
005308	B10.Cg-H2^d Tg(TcraCl4,TcrbCl4)1Shrm/ShrmJ
005534	B10.Cg-H2^d Tg(Ins2-HA)165Bri/ShrmJ
006102	B10.Cg-H2^k Tg(Il2/NFAT-luc)83Rinc/J
006100	B10.Cg-H2^k Tg(NFkB/Fos-luc)26Rinc/J
005895	B10.Cg-Thy1^a H2^d Tg(TcraCl1,TcrbCl1)1Shrm/J
002024	B10.D1-H2^q/SgJ
000462	B10.D2-H2^d/n2SnJ
001153	B10.D2-H2ⁱ⁷/(107R)EgJ
000460	B10.D2-Hc⁰ H2^d H2-T18^c/o2SnJ
000461	B10.D2-Hc⁰ H2^d H2-T18^c/oSnJ
000463	B10.D2-Hc¹ H2^d H2-T18^c/nSnJ
003147	B10.D2-Hc¹ H2^d H2-T18^c/nSnJ-Tg(DO11.10)10Dlo/J
001953	B10.S-H2^s/SgMcdJ
002995	B6 x C.B10-H2^b/LiMcdJ-Fbn2^fp-2J/J
005717	B6(NOD) H2^g7-Sostdc1^shk/J
003584	B6.129S2-H2^dlAb1-Ea/J
001148	B6.AK-H2^k/FlaEgJ
001895	B6.AK-H2^k/J
000360	B6.C-H2^d Mdmg1^BALB/cBy/aByJ
000359	B6.C-H2^d/bByJ
005715	B6.Cg H2^g7-Tg(Ins2-CD80)3B7Flv/LwnJ
003068	B6.NOD-(Csf2-D11Mit42) (D17Mit21-D17Mit10)/J
003300	B6.NOD-(D17Mit21-D17Mit10)/LtJ
003069	B6.NOD-(D1Mit3-Bcl2) (D17Mit21-D17Mit10)/LtJ
003071	B6.NOD-(D1Mit5.1-D1Mit15) (D17Mit21-D17Mit10)/J
003067	B6.NOD-(D3Mit132-Tshb) (D17Mit21-D17Mit10)/J
003066	B6.NOD-(D6Mit54-D6Mit14) (D17Mit21-D17Mit10)/J
000944	B6.SJL-H2^b C3^c/2CyJ
000966	B6.SJL-H2^s C3^c/1CyJ
000945	B6.SW/1CyJ
003374	B6;129S2-H2^dlAb1-Ea/J
003240	B6;B10.A-H2^a-Tg(H2KmPCC)2939Stoe/J
002844	BALB.5R-H2ⁱ⁵/LilJ
001041	BKS.B6-H2^b/J
001892	BRVR.B10-H2^b/J
001893	BRVR.D2-H2^d/J
001952	C.B10-H2^b/LilMcdJ
001951	C.C3-H2^k/LilMcdJ
000438	C3.SW-H2^b/SnJ
000437	D1.C-H2^d H2-T18^c/SnJ
000435	D1.LP-H2^b H2-T18^b^?/SnJ
001383	LT.MA-Glo1^b H2^k/J
002591	NOD.B10Sn-H2^b/J
004447	NOD.Cg-H2^h4/DilTacUmmJ
002032	NOD.SW-H2^q/J
001627	NON.NOD-H2^g7/LtJ
003153	WLC.C-H2^d.GR-Mtv2/MorJ
003154	WLC.C-H2^d/MorJ

Strain Name:

B10.A-H2h2/(2R)SgSnJ

Stock Number:

000468

Availability:

Repository- Live

Strain Information

Control Information

Related Strains

Additional Web Information

Phenotype Information

Gene & Allele Information

Genotyping Information

Helpful Links

References

Additional References

Health & Colony Maintenance Information

Animal Health Reports

Colony Maintenance

Pricing, Supply Level & Notes, Controls, General Terms & Conditions

Pricing

Additional Supply Details

Additional Supply Details

Supply Details

Control Information

General Terms and Conditions

See Terms of Use

The Jackson Laboratory's Genotype Promise

Terms of Use

Contact information

Contracts Administration

JAX® Mice & Services Conditions of Use

No Warranty

No Liability

B10.A-H2^h2/(2R)SgSnJ

JAX^® Mice & Services Conditions of Use