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Strain Name: |
B6CBACa Aw-J/A-Gs/J |
Stock Number: |
000500 |
Availability:
| Repository-Cryopreserved |
Product Information
Strain Details
| Type |
JAX® GEMM® Strain -
Mutant Strain |
| Additional information on
JAX® GEMM® Strains. |
| Type |
JAX® GEMM® Strain -
Spontaneous Mutation |
| Species | laboratory mouse |
| Generation | N21p
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Mammalian Phenotype Terms assigned by genotype
The following phenotype information may relate to a genetic background differing from this JAX® Mice strain.
Gs/Gs
Background
Not Specified
- skin/coat/nails phenotype
- abnormal coat appearance
(MGI Ref ID J:15053)
Gs/Gs+
Background
Not Specified
- limbs/digits/tail phenotype
- polydactyly
(MGI Ref ID J:11266)
- occasionally seen in hallux region of rear feet
- syndactyly
(MGI Ref ID J:11266)
- involves mainly digits 1 and 2 of both or either front or rear feet
- skin/coat/nails phenotype
- abnormal coat appearance
(MGI Ref ID J:11266)
- striped appearance resembles heterozygous tabby, Eda, females
Gs/Y
Background
Not Specified
- skin/coat/nails phenotype
- abnormal coat appearance
(MGI Ref ID J:30359)
- skin and hair follicles are normal
- lipid abnormality is predicted
- greasy coat
(MGI Ref ID J:15053)
- coat looks and feels oily
- abnormal hair texture
(MGI Ref ID J:30359)
- rough hair
(MGI Ref ID J:30359)
- mice older than 7 months have a rough, greasy coat
- abnormal zigzag hairs
(MGI Ref ID J:30359)
- sharp angulation at characteristic constrictions of these hairs is missing
- hair of 7 month old mice comprises almost exclusively this hair type
- darkened coat color
(MGI Ref ID J:30359)
- hair is darker, less yellow pigment
- pigmentation phenotype
- darkened coat color
(MGI Ref ID J:30359)
- hair is darker, less yellow pigment
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Gene & Allele Details
| Allele Symbol |
Aw-J |
| Allele Name |
white bellied agouti Jackson |
| Common Name(s) |
AWJ;
|
| Strain of Origin | C57BL/6J |
| Gene Symbol and Name |
a, nonagouti |
| Chromosome |
2 |
| Gene Common Name(s) |
AGSW;
AGTI;
AGTIL;
ASP;
As;
MGC126092;
MGC126093;
SHEP9;
agouti;
agouti signal protein;
agouti suppressor;
|
| |
| Allele Symbol |
Gs |
| Allele Name |
greasy |
| Molecular Note |
The Gs mutation was discovered among later descendants of an irradiated male, but is probably of spontaneous origin. |
Genotyping Protocols
Aw-J
Related Strains
Strains carrying Aw-J allele
View Strains carrying Aw-J (31 strains)
Strains carrying other alleles of a
View Strains carrying other alleles of a (138 strains)
Research Applications
This mouse can be used to support research in many areas including:
Gs related
Dermatology Research
Skin and Hair Texture Defects
References
Additional References
Price and Supply Information
| Strain Name: |
B6CBACa Aw-J/A-Gs/J |
| Stock Number: |
000500 |
Price Details
IMPORTANT NOTE: Prices are based on shipping destination.
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Supply Details
| Standard Supply | Repository-Cryopreserved. Must Be Recovered. Please refer to pricing and supply notes for further information. |
| Supply Notes |
Cryorecovery - Standard. The recovery process begins when a signed agreement form is returned to the Customer Service Department after order placement. Although results vary by strain, at least two males and two females (two pairs) will be provided, typically within 15 weeks of our receipt of the signed agreement form. If the first recovery attempt is unsuccessful or only one pair is recovered, a second recovery will be done, extending the delivery time to approximately 25 weeks. At least one member of each pair will be of known genotype and will carry the mutation if it is a mutant strain. Please note that pairs may not reflect the mating scheme utilized by The Jackson Laboratory prior to cryopreservation of the strain. Mating schemes are sometimes modified for successful cryopreservation. Price represents a repository maintenance fee, which includes the cost of recovery of the strain from the cryopreservation resource and the periodic replacement of the frozen embryos used for recovery.
Cryorecovery to establish a Dedicated Supply for greater quantities of mice. One to two pairs will be recovered to establish a Dedicated Supply of mice. Price by quotation. For more information on Dedicated Supply, please contact JAX® Services: Tel: 1-800-422-6423 or 1-207-288-5845; Email: jaxservices@jax.org.
Genomic DNA is available for this strain from the Mouse DNA Resource.
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| Licensing | See General Terms and Conditions below
|
General Terms and Conditions
View
JAX® Mice & Services Conditions of Use.
The Jackson Laboratory's Genotype Promise
The Jackson Laboratory has rigorous genetic quality control and mutant gene
genotyping programs to ensure the genetic background of JAX
® Mice strains as
well as the genotypes of strains with identified molecular mutations.
JAX
® Mice strains are only made available to researchers after meeting our
standards. However, the phenotype of each strain may not be fully
characterized and/or captured in the strain data sheets.
Therefore, we
cannot guarantee a strain's phenotype will meet all expectations. To
ensure that JAX
® Mice will meet the needs of individual research projects
or when requesting a strain that is new to your research, we suggest ordering
and performing tests on a small number of mice to determine suitability for
your particular project.
Ordering and Purchasing Information
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Tel: 800.422.6423 or 207.288.5845
Fax: 207.288.6150
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