Description

Strain Information

Former Names MOL 3-III    (Changed: 15-DEC-04 ) Type Inbred Strain; Additional information on Inbred Strains. Type Wild-Derived; Additional information on Wild-Derived Mice. Visit our online Nomenclature tutorial. Mating System Sibling x Sibling         (Female x Male)   01-MAR-06 Species M. m. molossinus Generation F17+56 (30-OCT-09) Geographic Origin Fukuoka, Kyushu, Japan

Appearance
white-bellied agouti
Related Genotype: A^w/A^w

Description
A 7 base pair deletion was reported in the Cd4 5' untranslated region of Stock No. 000550, MOLF/EiJ (Wade et al., 1993, Capparelli et al., 2004). Subsequent testing at The Jackson Laboratory indicated that MOLC/EiJ, MOLD/EiJ and MOLG/EiJ also carry the variant sequence. The deletion is not believed to affect expression.

Development
In 1969 Dr. Michael Potter at NCI sent to Dr. Eva Eicher and Dr Thomas Roderick at The Jackson Laboratory 10 M. m. molossinus from a population that was within 1 to 3 generations of the wild population captured in Fukuoka, Kyushu, Japan. Dr. Roderick generated three inbred lines from single pairings of these mice and named them MOLC/Rk, MOLD/Rk, and MOLF/Rk. MOLC/Rk derived from the line he designated MOL 3-I, and MOLD/Rk and MOLE/Rk derived from the line designated MOL 3-III. MOLG/DnJ was split off as a substrain from MOLC/Rk at F14. (Roderick, 1982.)

Additional Web Information

JAX^® NOTES, Winter 1994; 456. Differences between MOLF/Ei, MOLD/Rk and MOLG/Dn.
JAX^® NOTES, Winter 1995; 460. Wild-Derived Mice Strains - Tips on Their Care and Handling.

Phenotype

Phenotype Information

View Research Applications

Research Applications

This mouse can be used to support research in many areas including:

Research Tools
Genetics Research
      Evolution and Systematics Research
      Gene Mapping: Polymorphisms

Genes & Alleles

Gene & Allele Information

Currently there are no related genes or alleles for this strain.

Genotyping

Genotyping Information

This strain will not have a genotyping protocol or one is not currently available.

Helpful Links

Genotyping resources and troubleshooting

References

References

Additional References

Capparelli R; Costabile A; Viscardi M; Iannelli D. 2004. Monoallelic expression of mouse Cd4 gene. Mamm Genome 15(8):579-84. [PubMed: 15457337]  [MGI Ref ID J:93064]

Wade N; Flaherty L. 1993. DNA sequence analysis and polymorphism of the mouse CD4 gene. Immunogenetics 38(5):384. [PubMed: 8344730]  [MGI Ref ID J:16098]

Health & husbandry

Health & Colony Maintenance Information

Animal Health Reports

Room Number           A2A

Colony Maintenance

Breeding & Husbandry	These mice are small and may need to delay weaning until 4+ weeks.
Mating System	Sibling x Sibling         (Female x Male)   01-MAR-06

Purchasing information

Pricing, Supply Level & Notes, Controls, General Terms & Conditions

Pricing

Supply Details

Standard Supply

Repository-Live. A collection of over 1000 strains maintained as live colonies. Individual colonies are sized to meet current customer demand. Delivery for orders of 10 mice or less ranges on average from one to eight weeks; mice are generally shipped between four to six weeks of age with a maximum shipping age of approximately nine weeks. Colony sizes do not generally support stringent age specifications for large volumes of mice; however custom orders and larger quantities of mice are easily arranged. Estimated ship dates for all orders provided within two business days following order placement.

Supply Notes

Usually shipped between four and eight weeks of age. This strain is included in the Mouse Mutant Resource collection. Genomic DNA is available for this strain from the Mouse DNA Resource.

Payment Terms and Conditions

Terms are granted by individual review and stated on the customer invoice(s) and account statement. These transactions are payable in U.S. currency within the granted terms. Payment for services, products, shipping containers, and shipping costs that are rendered are expected within the payment terms indicated on the invoice or stated by contract. Invoices and account balances in arrears of stated terms may result in The Jackson Laboratory pursuing collection activities including but not limited to outside agencies and court filings.

See Terms of Use tab for General Terms and Conditions

The Jackson Laboratory's Genotype Promise

The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX^® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX^® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX^® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.

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Ordering and Purchasing Information

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Contact Information
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Terms of Use

Terms of Use

General Terms and Conditions

Contact information

General inquiries

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phone:	207-288-6470
fax:	207-288-6655

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