JAX Mice Database - 000578 B6 x STOCK Tyr<c-ch> Bmp5<se> +/+ Myo6<sv>/J

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Strain Name:	B6 x STOCK Tyr^c-ch Bmp5^se +/+ Myo6^sv/J
Stock Number:	000578
Availability:	Repository- Live

Price and Supply Information
General Terms and Conditions

Genes & Alleles

Bmp5; Bmp5^se; Myo6; Myo6^sv; Tyr; Tyr^c-ch;

Product Information

Strain Details

Type JAX^® GEMM^® Strain - Mutant Stock

Additional information on JAX^® GEMM^® Strains.

Species laboratory mouse

Generation ?+F14 (06-DEC-07)

Strain Description
Mice homozygous for the Snell's waltzer spontaneous mutation (Myo6^sv) show to a marked degree the typical circling, head-tossing, deafness, and hyperactivity of other mutant mice of this type. Homozygous mutant mice are recognizable by the age of 1 week. The abnormalities of the inner ear consist of degeneration of the entire neuroepithelium comprising the organ of Corti, the saccular and utricular maculae, and the cristae of all three semicircular canals. Although viability of homozygotes is nearly normal, breeding ability is reduced and males are more reliable breeders than females.
Specific cytoskeletal components are critical for specific cellular structures. The microvilli of intestinal brush border cells in Myo6^sv homozygotes are shorter than normal. While myosin 6 is not critical for the development of hair cell stereocilia, it is essential for their maintenance. At birth the stereocilia appear nearly normal with only occasional stereocilia showing early signs of fusion at their bases, but by 3 days of age most hair cells appear disorganized with full fusing of steriocilia. Continued degeneration yields giant stereocilia by 20 days of age and degeneration of the inner and outer hair cells in the organ of Corti by 6 weeks of age. Reissner's membrane, the stria vascularis, and the spiral ganglion appear normal. At 20 or 30 days of age, direct cochlear stimulation failed to elicit a compound action potential or cochlear microphonic response indicating deafness in Myo6^sv homozygotes. A mutation in human MYO6 has been associated with a nonsyndromic dominant form of deafness. (Deol and Green, 1966; Avraham et al., 1995; Self et al., 1999; Melchoinda et al., 2001; Buss et al., 2001.)
Although myosin 6 co-localization with clatherin-coated pits suggests a role in endocytosis, Self et al. reported uptake of the membrane dye FM1-43 by hair cells of 1 and 3 day old Myo6^sv mutant mice indicating that endocytosis by hair cells does not require MYO6. Fibroblast cell lines from mice homozygous for the Myo6^sv mutation have a 40% reduction in the level of trans-Golgi network secretion to the plasma membrane paralleling a 40% reduction in Golgi volume. Additionally, the mutant Golgi complexes are smaller and more fragmented than normal. Transfection of fibroblasts from Myo6^sv homozygotes with full length myosin 6 returns the Golgi morphology and secretion to normal. (Self et al., 1999; Warner et al., 2003.) In addition to cochlear defects, homozygous mice exhibit a significant reduction in the amplitude of a and b waves as measured by electroretinogram, although there is no photoreceptor cell loss. (Kitamoto et al., 2005)
The Snell's waltzer mutation is maintained in repulsion with the closely linked short ear mutation (Bmp^se), both located on Chromosome 9.
Strain Development
The chinchilla (Tyr^c-ch) mutation arose spontaneously in the 1920's (Feldman H. W. 1922 Am. Nat. 56:573-574). Short ear (Bmp5^se) arose spontaneously in mice obtained from a commercial breeder about 1921 (Lynch C.H. 1921 Am. Nat. 55:421-426). The Snell's waltzer (Myo6^sv) mutation was found in the B10.HA(33NX) stock of Dr. G.D. Snell at the Jackson Laboratory in the late 1950s. In 1959 an Myo6^sv/Myo6^sv mouse was crossed to the SEC/1 strain of Dr. M. C. Green. The genotype of SEC/1 was a/a Tyrp1^b/Tyrp1^b Tyr^c-ch/Tyr^c-ch Bmp5^se/+. A very close linkage was found between Bmp5^se and Myo6^sv and the two loci were maintained in repulsion. The stock was inbred as Tyr^c-ch/Tyr^c-ch Bmp5^se +/+ Myo6^sv and was cryopreserved in 1983 by crossing C57BL/6J females to Tyr^c-ch/Tyr^c-ch Bmp5^se +/+ Myo6^sv at F67 to generate embryos.

Related Disease (OMIM) Terms

Deafness, Autosomal Dominant Nonsyndromic Sensorineural 22; DFNA22

Deafness, Congenital Neurosensory, Autosomal Recessive 37; DFNB37

Ear, Patella, Short Stature Syndrome

Mammalian Phenotype Terms assigned by genotype

Myo6^sv/Myo6⁺
B6 x STOCK Tyr^c-ch Bmp5^se +/+ Myo6^sv/J
hearing/vestibular/ear phenotype

reduced linear vestibular evoked potential (MGI Ref ID J:116914)

elevated threshold and reduced amplitudes

Myo6^sv/Myo6^sv
B6 x STOCK Tyr^c-ch Bmp5^se +/+ Myo6^sv/J
hearing/vestibular/ear phenotype

absent linear vestibular evoked potential (MGI Ref ID J:116914)

VESPs are absent at the maximum stimulus intensity used

circling (MGI Ref ID J:116914)

behavior/neurological phenotype

abnormal reflex (MGI Ref ID J:116914)

abnormal drop reflex; mice do not demonstrate expected dorsoflexion and spread out the front paws when quickly lowered from ~20 cm above a table surface, while controls do exhibit this behavior

circling (MGI Ref ID J:116914)

impaired swimming (MGI Ref ID J:116914)

mice exhibit poor swimming ability; mice can not maneuver in the water and can not remain at the surface

The following phenotype information may relate to a genetic background differing from this JAX^® Mice strain.
Bmp5^se/Bmp5^se
SEC/Gn
skeleton phenotype

abnormal cartilage development (MGI Ref ID J:13011)

cartilage forms more slowly in healing rib fractures

abnormal osteogenesis (MGI Ref ID J:13011)

reduced rate of proliferation of osteogenic cells of the periosteum in healing rib fractures

Bmp5^se/Bmp5^se
SEC/1Gn
skeleton phenotype

abnormal cartilage development (MGI Ref ID J:13011)

cartilage forms more slowly in healing rib fractures

cardiovascular system phenotype

abnormal artery morphology (MGI Ref ID J:5086)

the right renal artery lies ventral to the posterior vena cava rather than dorsal to it as in controls

immune system phenotype

granulomatous inflammation (MGI Ref ID J:5086)

granulomas are seen on the ventral surface of the central and left lateral lobes of the liver

liver/biliary system phenotype

abnormal liver morphology (MGI Ref ID J:5086)

increase in liver lesions, mainly due to an increase in granulomas

respiratory system phenotype

lung cysts (MGI Ref ID J:5086)

have numerous small cysts in the lungs

Myo6^sv/Myo6^sv
involves: B10.HA/(33NX)Sn * C57BL/6J
behavior/neurological phenotype

hyperactivity (MGI Ref ID J:29898)

stereotypic behavior (MGI Ref ID J:29898)

circling (MGI Ref ID J:29898)

mutants can be identified by circling behavior

head bobbing (MGI Ref ID J:134368)

mutants can be identified by head bobbing

head tossing (MGI Ref ID J:29898)

growth/size phenotype

decreased body size (MGI Ref ID J:86379)

slightly reduced body size

hearing/vestibular/ear phenotype

abnormal cochlear sensory epithelium morphology (MGI Ref ID J:29898)

in adults there was degeneration of the entire neuroepithelium in the inner ear

cochlear hair cell degeneration (MGI Ref ID J:29898)

hair cell degeneration apparent by 3 weeks of age

cochlear inner hair cell degeneration (MGI Ref ID J:29898)

by 6 weeks of age, inner hair cells in the organ of Corti were lost

cochlear outer hair cell degeneration (MGI Ref ID J:29898)

by 6 weeks of age, outer hair cells in the organ of Corti were lost

fused inner hair cell stereocilia (MGI Ref ID J:58030)

cochlear hair cells appear to start develop normally, but from around birth these arrays become progressively more disorganized and the stereocilia fuse

by 3 days after birth, practically all hair cells are affected, and stereocilia fusion is extensive

fused outer hair cell stereocilia (MGI Ref ID J:58030)

cochlear hair cells appear to start develop normally, but from around birth these arrays become progressively more disorganized and the stereocilia fuse

by 3 days after birth, practically all hair cells are affected, and stereocilia fusion is extensive

absent cochlear nerve compound action potential (MGI Ref ID J:29898)

no action potentials generated in the cochlear nerve by direct cochlear stimulation

circling (MGI Ref ID J:29898)

mutants can be identified by circling behavior

head bobbing (MGI Ref ID J:134368)

mutants can be identified by head bobbing

head tossing (MGI Ref ID J:29898)

organ of Corti degeneration (MGI Ref ID J:29898)

in adults

reproductive system phenotype

reduced fertility (MGI Ref ID J:29898)

both sexes were fertile but with reduced productivity

nervous system phenotype

absent cochlear nerve compound action potential (MGI Ref ID J:29898)

no action potentials generated in the cochlear nerve by direct cochlear stimulation

cochlear hair cell degeneration (MGI Ref ID J:29898)

hair cell degeneration apparent by 3 weeks of age

cochlear inner hair cell degeneration (MGI Ref ID J:29898)

by 6 weeks of age, inner hair cells in the organ of Corti were lost

cochlear outer hair cell degeneration (MGI Ref ID J:29898)

by 6 weeks of age, outer hair cells in the organ of Corti were lost

fused inner hair cell stereocilia (MGI Ref ID J:58030)

cochlear hair cells appear to start develop normally, but from around birth these arrays become progressively more disorganized and the stereocilia fuse

by 3 days after birth, practically all hair cells are affected, and stereocilia fusion is extensive

fused outer hair cell stereocilia (MGI Ref ID J:58030)

cochlear hair cells appear to start develop normally, but from around birth these arrays become progressively more disorganized and the stereocilia fuse

by 3 days after birth, practically all hair cells are affected, and stereocilia fusion is extensive

vision/eye phenotype

*normal* vision/eye phenotype (MGI Ref ID J:134368)

retinal morphology appears normal; photoreceptor ultrastructure and photoreceptor counts in animals aged 224-303 days are not different from controls

abnormal eye electrophysiology (MGI Ref ID J:134368)

in mutants 42-48 days old, a- and b-waves in electroretinogram are reduced in amplitude (25 and 30% respectively) compared to littermate controls

intensity-response curves are reduced in amplitude by 20% at flash intensities above 3.0 and 6.0 log units of attenuation for a- and b-waves, respectively000

amplitudes are similary reduced in mutants 254-257 days of age

Gene & Allele Details

Allele Symbol		Bmp5^se
Allele Name		short ear
Common Name(s)		se^GnJ;
Strain of Origin		mice from Abbie Lathrop mouse farm
Gene Symbol and Name		Bmp5, bone morphogenetic protein 5
Chromosome		9
Gene Common Name(s)		AU023399; MGC34244; expressed sequence AU023399; se; short ear;
Molecular Note		The C to T transition creates a stop codon at amino acid 208. The resulting truncated protein does not include the carboxy terminal signaling portion of the molecule. [MGI Ref ID J:21484]

Allele Symbol		Myo6^sv
Allele Name		Snell's waltzer
Common Name(s)		sv;
Strain of Origin		B10.HA/(33NX)Sn
Gene Symbol and Name		Myo6, myosin VI
Chromosome		9
Gene Common Name(s)		BC029719; DFNA22; DFNB37; KIAA0389; RGD1560646; Snell's waltzer; cDNA sequence BC029719; sv;
Molecular Note		On the basis of a series of southern blots, this mutation appears to involve a 1.1 kb intragenic deletion. Gene transcripts could be detected by RT-PCR. Sequence analysis of these transcripts identified a 150 bp deletion corresponding to nucleotides 2456-2585. The deletion results in a frame shift which introduces a stop codon at the beginning of the neck region. [MGI Ref ID J:29898]

Allele Symbol		Tyr^c-ch
Allele Name		chinchilla
Common Name(s)		c^ch; c^r;
Strain of Origin		fancier's stock
Gene Symbol and Name		Tyr, tyrosinase
Chromosome		7
Gene Common Name(s)		C; OCA1A; OCAIA; SHEP3; albino; c; skc35; skin/coat color 35;
Molecular Note		The mutation in the chinchilla allele was found to be a G to A point mutation that results in an amino acid change at position 464 from alanine to threonine. [MGI Ref ID J:19279]

Control Information

	Control
	? +/+ ? untested from colony

Considerations for Choosing Controls
Control Pricing Information for JAX^® GEMM^® Strains

Related Strains

Strains carrying Bmp5^se allele

000004 ABP/LeJ

000056 B6.Cg-Bmp5^se/J

000285 B6.Cg-Rora^sg + +/+ Myo5a^d Bmp5^se/J

000253 DLS/LeJ

000644 SEA/GnJ

000270 SEC/1GnLeJ

View Strains carrying Bmp5^se (6 strains)

Strains carrying Tyr^c-ch allele

000091 129T1/Sv-Oca2⁺ Tyr^c-ch Dnd1^Ter/J

001279 129T1/Sv-Oca2⁺ Tyr^c-ch-Aft/J

000619 FS/EiJ

004828 FVB.129P2-Pde6b⁺ Tyr^c-ch/AntJ

000271 SH1/LeJ

000306 STOCK Dll3^pu + Tyr^c-ch/+ Oca2^p Tyr^c-ch/J

View Strains carrying Tyr^c-ch (6 strains)

Strains carrying other alleles of Bmp5

001496 C57BL/6J-Bmp5^se-4J/J

005420 C;129S7 Gt(ROSA)26Sor-Bmp5^cfe-se7J/J

005421 CBy;B6-Bmp5^cfe-se8J/J

View Strains carrying other alleles of Bmp5 (3 strains)

Strains carrying other alleles of Myo6

008456 129S1/SvImJ-Myo6^sv-4J/J

006124 B6.Cg-Myo6^sv-2J/J

005749 C57BL/6J-Myo6^sv-3J/J

View Strains carrying other alleles of Myo6 (3 strains)

Strains carrying other alleles of Tyr

000090 129S1/Sv-Oca2⁺ Tyr⁺ Kitl^Sl-J/J

005445 A.B6 Tyr⁺-Cyba^nmf333/J

005012 A.B6 Tyr⁺-Myo5a^d-l31J/J

002565 A.B6-Tyr⁺/J

001017 AKXD10/TyJ

000765 AKXD13/TyJ

000954 AKXD15/TyJ

000958 AKXD16/TyJ

001093 AKXD18/TyJ

001062 AKXD21/TyJ

000947 AKXD22/TyJ

000969 AKXD24/TyJ

000777 AKXD6/TyJ

000763 AKXD9/TyJ

000409 B10.129P-H1^b Hbb^d Tyr^c Ea7^a/(5M)oSnJ

000418 B10.129P-H1^b Tyr^c Hbb^d/(5M)nSnJ

000432 B10.C-H1^b Hbb^d Tyr^c/(41N)SnJ

000580 B10.D2/nSn-Tyr^c-4J/J

000822 B6 x 129S1/SvEi Oca2⁺ Tyr⁺-Vsx2^or-J/J

000058 B6(Cg)-Tyr^c-2J/J

000383 B6.C-Tyr^c H1^b Hbb^d/ByJ

007484 B6.Cg-Tyr^c-2J Tg(Tyr)3412ARpw Tg(Sry-EGFP)92Ei/EiJ

000035 B6.Cg-Tyr^c-J/J

000104 B6.Cg-Tyr^c-h/J

000054 B6.D2-Tyr^c-p/J

000899 C.B6-Tyr⁺ Hbb^s/J

000339 C3H/HeJ-Tyr^c-9J/J

001294 C3H/HeJ-Tyr^c-a/J

001002 C57BL/10SnJ-Tyr^c-11J/J

001006 CBA/J-Tyr^c-10J/J

000657 CE/J

007483 FVB.Cg-Tg(Tyr)3412ARpw Tg(Sry-EGFP)92Ei/EiJ

000494 J.Cg-Oca2⁺ Tyr⁺ Lyst^bg/J

002281 NFS.C58-Tyr⁺/J

004304 NOD.CBALs-Tyr⁺/LtJ

005115 NOD.FVB-Tg(INS-MT2A,Tyr)1Pne/PneJ

005114 NOD.FVB-Tg(Ins1-Cat,Tyr)25Pne/PneJ

001759 STOCK A Tyr^c Sha/J

000006 STOCK Hk Tyr^c/J

000206 STOCK a/a Tyr^c-h/J

View Strains carrying other alleles of Tyr (40 strains)

Animal Health Reports

Room Number A1

Research Applications

This mouse can be used to support research in many areas including:

Bmp5^se related

Developmental Biology Research
Growth Defects
Skeletal Defects

Myo6^sv related

Cell Biology Research
Vesicular Trafficking

Mouse/Human Gene Homologs
deafness, autosomal dominant nonsyndromic sensorineural 22 (DFNA22)
deafness, autosomal recessive nonsyndromic sensorineural 37 (DFNB37)

Neurobiology Research
Vestibular and Hearing Defects

Sensorineural Research
Vestibular and Hearing Defects

Tyr^c-ch related

Dermatology Research
Color and White Spotting Defects

Developmental Biology Research
Neurodevelopmental Defects
Skeletal Defects

Mouse/Human Gene Homologs
albinism, tyrosine negative

References

Additional References

Price and Supply Information

Strain Name:	*B6 x STOCK Tyr^c-ch Bmp5^se* +/+ Myo6^sv/J**
Stock Number:	000578

Price Details

IMPORTANT NOTE: Prices are based on shipping destination. The shipping destinations are:

USA, Canada and Mexico
International

*Pricing for Shipping Destination selected:

International

Price(s) in US dollars ($)		Genotype(s) Provided
Individual Mouse Price	$264.20	Genes in Repulsion; Assumed Wild-type for Bmp5^se (Untested), Homozygous for Myo6^sv
Individual Mouse Price	$264.20	Genes in Repulsion; Homozygous for Bmp5^se, Assumed Wild-type for Myo6^sv (Untested)
Pair	$326.90	Genes in Repulsion; Assumed Heterozygous for Bmp5^se (Untested), Heterozygous for Myo6^sv (Tested) x Genes in Repulsion; Assumed Heterozygous for Bmp5^se (Untested), Heterozygous for Myo6^sv (Tested)	tested for Myo6^sv
Pair	$326.90	Genes in Repulsion; Heterozygous for Bmp5^se (Tested), Assumed Heterozygous for Myo6^sv (Untested) x Genes in Repulsion; Heterozygous for Bmp5^se (Tested), Assumed Heterozygous for Myo6^sv (Untested)	tested for Bmp5^se
Pair	$326.90	Genes in Repulsion; Heterozygous for Bmp5^se (Tested), Heterozygous for Myo6^sv (Tested) x Genes in Repulsion; Heterozygous for Bmp5^se (Tested), Heterozygous for Myo6^sv (Tested)	tested for Bmp5^se and Myo6^sv
Pair	$307.60	Genes is Repulsion; Assumed Heterozygous for Bmp5^se (Untested), Assumed Heterozygous for Myo6^sv (Untested) x Genes is Repulsion; Assumed Heterozygous for Bmp5^se (Untested), Assumed Heterozygous for Myo6^sv (Untested)	untested for Bmp5^se and Myo6^sv

Supply Details

Standard Supply	Repository-Live. A collection of over 1000 strains maintained as live colonies. Individual colonies are sized to meet current customer demand. Delivery for orders of 10 mice or less ranges on average from one to eight weeks; mice are generally shipped between four to six weeks of age with a maximum shipping age of ~nine weeks. Colony sizes do not generally support stringent age specifications for large volumes of mice; however custom orders and larger quantities of mice are easily arranged. Estimated ship dates for all orders provided within 48 hours of order placement.
Supply Notes	Histology and Tissue Collection Services are available for all JAX^® Mice strains. For more information, please contact Customer Service at orderquest@jax.org or 1-207-288-5845. Usually shipped between four and eight weeks of age. This strain is included in the Mouse Mutant Resource collection. Genomic DNA is available for this strain from the Mouse DNA Resource.
Licensing	See General Terms and Conditions below
Control Information	View Control Information in Strain Details. View Control Pricing Information for JAX^® Strains.

General Terms and Conditions

View JAX^® Mice & Services Conditions of Use.

The Jackson Laboratory's Genotype Promise

The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX^® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX^® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX^® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.

Ordering and Purchasing Information

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Tel: 800.422.6423 or 207.288.5845
Fax: 207.288.6150
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Go to JAX^® Mice Query Form

000004	ABP/LeJ
000056	B6.Cg-Bmp5^se/J
000285	B6.Cg-Rora^sg + +/+ Myo5a^d Bmp5^se/J
000253	DLS/LeJ
000644	SEA/GnJ
000270	SEC/1GnLeJ

000091	129T1/Sv-Oca2⁺ Tyr^c-ch Dnd1^Ter/J
001279	129T1/Sv-Oca2⁺ Tyr^c-ch-Aft/J
000619	FS/EiJ
004828	FVB.129P2-Pde6b⁺ Tyr^c-ch/AntJ
000271	SH1/LeJ
000306	STOCK Dll3^pu + Tyr^c-ch/+ Oca2^p Tyr^c-ch/J

001496	C57BL/6J-Bmp5^se-4J/J
005420	C;129S7 Gt(ROSA)26Sor-Bmp5^cfe-se7J/J
005421	CBy;B6-Bmp5^cfe-se8J/J

008456	129S1/SvImJ-Myo6^sv-4J/J
006124	B6.Cg-Myo6^sv-2J/J
005749	C57BL/6J-Myo6^sv-3J/J

000090	129S1/Sv-Oca2⁺ Tyr⁺ Kitl^Sl-J/J
005445	A.B6 Tyr⁺-Cyba^nmf333/J
005012	A.B6 Tyr⁺-Myo5a^d-l31J/J
002565	A.B6-Tyr⁺/J
001017	AKXD10/TyJ
000765	AKXD13/TyJ
000954	AKXD15/TyJ
000958	AKXD16/TyJ
001093	AKXD18/TyJ
001062	AKXD21/TyJ
000947	AKXD22/TyJ
000969	AKXD24/TyJ
000777	AKXD6/TyJ
000763	AKXD9/TyJ
000409	B10.129P-H1^b Hbb^d Tyr^c Ea7^a/(5M)oSnJ
000418	B10.129P-H1^b Tyr^c Hbb^d/(5M)nSnJ
000432	B10.C-H1^b Hbb^d Tyr^c/(41N)SnJ
000580	B10.D2/nSn-Tyr^c-4J/J
000822	B6 x 129S1/SvEi Oca2⁺ Tyr⁺-Vsx2^or-J/J
000058	B6(Cg)-Tyr^c-2J/J
000383	B6.C-Tyr^c H1^b Hbb^d/ByJ
007484	B6.Cg-Tyr^c-2J Tg(Tyr)3412ARpw Tg(Sry-EGFP)92Ei/EiJ
000035	B6.Cg-Tyr^c-J/J
000104	B6.Cg-Tyr^c-h/J
000054	B6.D2-Tyr^c-p/J
000899	C.B6-Tyr⁺ Hbb^s/J
000339	C3H/HeJ-Tyr^c-9J/J
001294	C3H/HeJ-Tyr^c-a/J
001002	C57BL/10SnJ-Tyr^c-11J/J
001006	CBA/J-Tyr^c-10J/J
000657	CE/J
007483	FVB.Cg-Tg(Tyr)3412ARpw Tg(Sry-EGFP)92Ei/EiJ
000494	J.Cg-Oca2⁺ Tyr⁺ Lyst^bg/J
002281	NFS.C58-Tyr⁺/J
004304	NOD.CBALs-Tyr⁺/LtJ
005115	NOD.FVB-Tg(INS-MT2A,Tyr)1Pne/PneJ
005114	NOD.FVB-Tg(Ins1-Cat,Tyr)25Pne/PneJ
001759	STOCK A Tyr^c Sha/J
000006	STOCK Hk Tyr^c/J
000206	STOCK a/a Tyr^c-h/J

Strain Name:

B6 x STOCK Tyrc-ch Bmp5se +/+ Myo6sv/J

Stock Number:

000578

Availability:

Repository- Live

Price and Supply Information

General Terms and Conditions

Product Information

Strain Details

Myo6sv/Myo6+

Myo6sv/Myo6sv

Bmp5se/Bmp5se

Bmp5se/Bmp5se

Myo6sv/Myo6sv

Gene & Allele Details

Control Information

Related Strains

Animal Health Reports

Research Applications

References

Price and Supply Information

Price Details

*Pricing for Shipping Destination selected:

International

Supply Details

General Terms and Conditions

The Jackson Laboratory's Genotype Promise

B6 x STOCK Tyr^c-ch Bmp5^se +/+ Myo6^sv/J

Myo6^sv/Myo6⁺

Myo6^sv/Myo6^sv

Bmp5^se/Bmp5^se

Bmp5^se/Bmp5^se

Myo6^sv/Myo6^sv