Strain Name: |
B6-Gpi1b x B6CBCa Aw-J/A-T(7;15)9H Gpi1a/J |
|---|---|
Stock Number: |
000600 |
Availability: | Repository-Cryopreserved |
General Terms and Conditions |
| Former Name |
B6-Gpi1b x B6CBACa-Aw-J/A-T(7;15)9H Gpi1a (Changed: 15-DEC-04
) |
| Genes & Alleles | Aw-J; Gpi1; Gpi1a; Gpi1b; a; T(7;15)9H; ; |
Product Information
Strain Details
Type Chromosome Aberration Additional information on Mice with Chromosomal Aberrations. Type JAX® GEMM® Strain - Mutant Strain Additional information on JAX® GEMM® Strains. Type Translocation Additional information on Mice with Chromosomal Aberrations. Species laboratory mouse Generation N7 F1+F8+N1
Gene & Allele Details
| Allele Symbol | Aw-J | ||
|---|---|---|---|
| Allele Name | white bellied agouti Jackson | ||
| Common Name(s) | AWJ; | ||
| Strain of Origin | C57BL/6J | ||
| Gene Symbol and Name | a, nonagouti | ||
| Chromosome | 2 | ||
| Gene Common Name(s) | AGSW; AGTI; AGTIL; ASP; As; MGC126092; MGC126093; SHEP9; agouti; agouti signal protein; agouti suppressor; | ||
| Allele Symbol | Gpi1a | ||
| Allele Name | a variant | ||
| Gene Symbol and Name | Gpi1, glucose phosphate isomerase 1 | ||
| Chromosome | 7 | ||
| Gene Common Name(s) | AMF; GNPI; Gpi-1; Gpi-1r; Gpi-1s; Gpi-1t; Gpi1-r; Gpi1-s; Gpi1-t; NLK; Org; PGI; PHI; SA-36; glucose phosphate isomerase 1, regulatory; glucose phosphate isomerase 1, structural; glucose phosphate isomerase 1, temporal; | ||
| Molecular Note | This allele determines a slower migrating variant of the encoded enzyme and occurs in the wild and in strains A/HeJ, AKR/J, BALB/cJ, C57BR/cdJ, C58/J, CE/J, DBA/2J, DE/J, DW/J, LP/J, MA/J, NZB, PL/J, P/J, RARF, RF/J, SJL/J, ST/bJ, and 129/J. Sequencing analysis identified four nucleotide differences between this allele and Gpi1b. Two differences were silent, while a third difference at position 282 predicts an aspartate for the a allele and an asparagine for the b allele. A fourth difference in the 3' untranslated region was also noted. [MGI Ref ID J:28033] | ||
| Allele Symbol | Gpi1b | ||
| Allele Name | b variant | ||
| Gene Symbol and Name | Gpi1, glucose phosphate isomerase 1 | ||
| Chromosome | 7 | ||
| Gene Common Name(s) | AMF; GNPI; Gpi-1; Gpi-1r; Gpi-1s; Gpi-1t; Gpi1-r; Gpi1-s; Gpi1-t; NLK; Org; PGI; PHI; SA-36; glucose phosphate isomerase 1, regulatory; glucose phosphate isomerase 1, structural; glucose phosphate isomerase 1, temporal; | ||
| Molecular Note | This allele determines a faster migrating variant of the encoded enzyme and occurs in the wild and in strains BUB/Bn, CBA/J, CBA/CaJ, C3Heb/FeJ, C57BL/6J, C57BL/6J-ob, SEA/GJ and SWR/J. Sequencing analysis identified four nucleotide differences between this allele and Gpi1b. Two differences were silent, while a third difference at position 282 predicts an aspartate for the a allele and an asparagine for the b allele. A fourth difference in the 3' untranslated region was also noted. [MGI Ref ID J:28033] | ||
| Gene Symbol and Name | T(7;15)9H, reciprocal translocation, Chr 7 and 15, Harwell 9 | ||
| Chromosome | 15 | ||
| Gene Common Name(s) | T9H; | ||
Genotyping Protocols
Aw-J
Related Strains
Reciprocal Translocations
View Reciprocal Translocations (47 strains)
000377 B6.C-H22c Gpi1a/(HW38)ByJ 000123 B6.C-H24c Gpi1a/(HW54)ByJ 001622 B6.CAST-Gpi1a.Cg-Hbath-J 000797 B6.CAST-Gpi1a/EiJ 002074 B6.Cg-Gpi1a Hbbd H1b/DehJ 001317 B6.Cg-Igha Thy1a Gpi1a/J 000909 B6CBy-Gpi1a/Gpi1b/J or Gpi1a-m1/Gpi1b/J 002800 C3.Cg-Gpi1a/J
005730 129S6.CB(B6)-Del(1)1Brk Gpi1b/Gpi1c/BrkMdfJ 000909 B6CBy-Gpi1a/Gpi1b/J or Gpi1a-m1/Gpi1b/J 003585 NOD.B6-(Gpi1-D7Mit346)/LtJ
Research Applications
This mouse can be used to support research in many areas including:
Gpi1a relatedResearch Tools
Genetics Research
Immunology and Inflammation Research
CD Antigens, Antigen Receptors, and Histocompatibility Markers
Research Tools
Genetics Research (Tissue/Cell Markers)
References
Additional ReferencesPrice and Supply Information
| Strain Name: | B6-Gpi1b x B6CBCa Aw-J/A-T(7;15)9H Gpi1a/J |
| Stock Number: | 000600 |
Price Details
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Supply Details
| Standard Supply | Repository-Cryopreserved. Must Be Recovered. Please refer to pricing and supply notes for further information. |
|---|---|
| Supply Notes |
Cryorecovery of Strains Needing Progeny Testing. The recovery process begins when a signed agreement form is returned to the Customer Service Department after order placement. Although results vary by strain, at least two untested males and two untested females (two pairs) will be recovered, typically within 15 weeks of our receipt of the signed agreement form. If the first recovery attempt is unsuccessful or only one pair is recovered, a second recovery will be done, extending the overall recovery time to approximately 25 weeks. However, all pups recovered will be sent. Progeny testing is required to identify the genotype of mice of this strain, as a genotyping assay is not available. This type of testing involves breeding the recovered animals and assessing the phenotype of the offspring in order to identify animals carrying the mutation of interest. We can perform the progeny testing for you as a service or we can ship all recovered animals (at least two untested pairs) to you for progeny testing at your facility. If you perform the progeny testing, there is NO guarantee that a carrier will be identified. If we perform progeny testing as a service, additional breeding time will be required. In this case, when a male and female (one pair) are identified that carry the mutation, they and their offspring will be shipped. Delivery time for strains requiring progeny testing often exceeds 25 weeks and may take 12 months or more due to the difficulties in breeding some strains. The progeny testing cost is in addition to the recovery cost and is based on the number of boxes used and the time taken to produce the mice identified as carrying the mutation. Please note that identified pairs may not reflect the mating scheme utilized by The Jackson Laboratory prior to cryopreservation of the strain. Mating schemes are sometimes modified for successful cryopreservation. Please contact Customer Service for more information on the cost of progeny testing for a strain: Tel: 1-800-422-6423 or 1-207-288-5845. Cryorecovery to establish a Dedicated Supply for greater quantities of mice |
| Licensing | See General Terms and Conditions below |
General Terms and Conditions
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The Jackson Laboratory's Genotype Promise
The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.Ordering and Purchasing Information
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