Strain Name: |
B6C3 a/A-T(10;13)199H +/+ Lystbg-J/J or Lystbg-2J/J |
|---|---|
Stock Number: |
000604 |
Availability: | Repository-Cryopreserved |
Price and Supply Information | |
General Terms and Conditions |
| Former Name |
B6C3H-a/A-T(10;13)199H +/+ Lystbg-J or Lystbg-2J (Changed: 15-DEC-04
) |
|
B6C3H-a/A-T199H +/+ Lystbg-J or Lystbg-2J (Changed: 15-DEC-04
) | |
|
T199H (Changed: 15-DEC-04
) | |
| Genes & Alleles | A; Lyst; Lystbg-2J; Lystbg-J; a; T(10;13)199H; ; |
Product Information
Strain Details
Type Chromosome Aberration Additional information on Mice with Chromosomal Aberrations. Type JAX® GEMM® Strain - Mutant Stock Additional information on JAX® GEMM® Strains. Type JAX® GEMM® Strain - Spontaneous Mutation Type Translocation Additional information on Mice with Chromosomal Aberrations. Species laboratory mouse Generation +N2
Gene & Allele Details
| Allele Symbol | A | ||
|---|---|---|---|
| Allele Name | wild type | ||
| Gene Symbol and Name | a, nonagouti | ||
| Chromosome | 2 | ||
| Gene Common Name(s) | AGSW; AGTI; AGTIL; ASP; As; MGC126092; MGC126093; SHEP9; agouti; agouti signal protein; agouti suppressor; | ||
| Allele Symbol | Lystbg-2J | ||
| Allele Name | beige 2 Jackson | ||
| Strain of Origin | Yellow stock | ||
| Gene Symbol and Name | Lyst, lysosomal trafficking regulator | ||
| Chromosome | 13 | ||
| Gene Common Name(s) | Beige; CHS; CHS1; D13Sfk13; DNA segment, Chr 13, Stephen F. Kingsmore 13; beige; bg; | ||
| General Note | The molecular fault in the Lystbg-2J mutation may be an intronic retrotransposition event causing decreased transcription and mRNA instability (J:34205). | ||
| Molecular Note | Quantitative reverse transcription showed a five-fold decrease in Lyst mRNA in mice homozygous for this allele. The molecular basis for this decrease is not known. [MGI Ref ID J:34205] | ||
| Allele Symbol | Lystbg-J | ||
| Allele Name | beige Jackson | ||
| Common Name(s) | bgj; | ||
| Strain of Origin | C57BL/6J | ||
| Gene Symbol and Name | Lyst, lysosomal trafficking regulator | ||
| Chromosome | 13 | ||
| Gene Common Name(s) | Beige; CHS; CHS1; D13Sfk13; DNA segment, Chr 13, Stephen F. Kingsmore 13; beige; bg; | ||
| General Note | This remutation occurred spontaneously in the C57BL/6J strain at The Jackson Laboratory (J:5311). It has essentially identical effects to the original Lystbg mutation, and has been used extensively in defining locus effects. | ||
| Molecular Note | This allele is defined by a noncomplementation test with Lystbg. Although mice homozygous for this allele show a decrease in Lyst mRNA in the liver compared to normal, the molecular basis for this allele is not yet known. [MGI Ref ID J:7539] | ||
| Allele Symbol | a | ||
| Allele Name | nonagouti | ||
| Gene Symbol and Name | T(10;13)199H, reciprocal translocation, Chr 10 and 13, Harwell 199 | ||
| Chromosome | 13 | ||
| Gene Common Name(s) | T199H; | ||
Related Strains
Reciprocal Translocations
View Reciprocal Translocations (47 strains)
003301 (C57BL/6J x C3H-Eya1bor)F1/J 002083 B6 x B6EiC3 a/A-T(7;16)235Dn/J 000507 B6 x B6EiC3 a/A-Otcspf/J 000628 B6.CE-A Amy1b Amy2b/J 004200 B6;CBACa Aw-J/A-Npr2cn-2J/J 001752 B6CBCa Aw-J/A-T(7;15)9H/J 006450 B6EiC3 a/A-Vss/J 000557 B6EiC3-+ a/LnpUl A/J 000504 B6EiC3Sn a/A-Cacnb4lh/J 000553 B6EiC3Sn a/A-Egfrwa2 Wnt3avt/J 001811 B6EiC3Sn a/A-Otcspf-ash/J 002343 B6EiC3Sn a/A-Otcspf/J 001923 B6EiC3Sn a/A-Ts(417)2Lws Tim/J 000200 C3FeB6 A/Aw-J-Ankank/J 000638 C3FeB6 A/Aw-J-Spnb4qv-J/J 000283 LT.CAST-A/J 001759 STOCK A Tyrc Sha/J
000509 C3H/HeJ-Lystbg-2J/J
000629 C57BL/6J-Lystbg-J/J
Research Applications
This mouse can be used to support research in many areas including:Lystbg-2J related
Lystbg-J relatedCardiovascular Research
Atherosclerosis
Dermatology Research
Color and White Spotting Defects
Hematological Research
Immunological Defects
Platelet Defects (platelet storage pool deficiency)
Immunology and Inflammation Research
CD Antigens, Antigen Receptors, and Histocompatibility Markers
Immunodeficiency
Intracellular Signaling Molecules
Internal/Organ Research
Kidney Defects (lysosomal enzyme abnormalities)
Metabolism Research
Mouse/Human Gene Homologs
Chediak-Higashi syndrome
Research Tools
Immunology and Inflammation Research (NK Cell Deficiency)
Cardiovascular Research
Atherosclerosis
Dermatology Research
Color and White Spotting Defects
Hematological Research
Immunological Defects
Platelet Defects (platelet storage pool deficiency)
Immunology and Inflammation Research
CD Antigens, Antigen Receptors, and Histocompatibility Markers
Immunodeficiency (NK Cell and Cd8 T Cell defects)
Immunodeficiency Associated with Other Defects
Intracellular Signaling Molecules
Internal/Organ Research
Kidney Defects (lysosomal enzyme abnormalities)
Metabolism Research
Mouse/Human Gene Homologs
Chediak-Higashi syndrome
Research Tools
Immunology and Inflammation Research (NK Cell Deficiency)
References
Additional ReferencesPrice and Supply Information
| Strain Name: | B6C3 a/A-T(10;13)199H +/+ Lystbg-J/J or Lystbg-2J/J |
| Stock Number: | 000604 |
Price Details
IMPORTANT NOTE: Prices are based on shipping destination. The shipping destinations are:
- USA, Canada and Mexico
- International
*Pricing for Shipping Destination selected:
International
| Price(s) in US dollars ($) | |||||
|---|---|---|---|---|---|
| Cryorecovery Fee | $2470.00 | ||||
Supply Details
| Standard Supply | Repository-Cryopreserved. Must Be Recovered. Please refer to pricing and supply notes for further information. |
|---|---|
| Supply Notes |
Cryorecovery - Standard. The recovery process begins when a signed agreement form is returned to the Customer Service Department after order placement. Although results vary by strain, at least two males and two females (two pairs) will be provided, typically within 15 weeks of our receipt of the signed agreement form. If the first recovery attempt is unsuccessful or only one pair is recovered, a second recovery will be done, extending the delivery time to approximately 25 weeks. At least one member of each pair will be of known genotype and will carry the mutation if it is a mutant strain. Please note that pairs may not reflect the mating scheme utilized by The Jackson Laboratory prior to cryopreservation of the strain. Mating schemes are sometimes modified for successful cryopreservation. Price represents a repository maintenance fee, which includes the cost of recovery of the strain from the cryopreservation resource and the periodic replacement of the frozen embryos used for recovery. Cryorecovery to establish a Dedicated Supply for greater quantities of mice. |
| Licensing | See General Terms and Conditions below |
General Terms and Conditions
View JAX® Mice & Services Conditions of Use.
The Jackson Laboratory's Genotype Promise
The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.Ordering and Purchasing Information
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