JAX Mice Database - 000636 B6C3Fe a/a-Lmx1a<dr-J>/J

Go to JAX^® Mice Query Form

Strain Name:	B6C3Fe a/a-Lmx1a^dr-J/J
Stock Number:	000636
Availability:	Repository- Live

Price and Supply Information
General Terms and Conditions

Former Name	B6C3Fe-a/a-Lmx1a^dr-J (Changed: 15-DEC-04 )
Genes & Alleles	Lmx1a; Lmx1a^dr-J; a;

Product Information

Strain Details

Type JAX^® GEMM^® Strain - Mutant Strain

Additional information on JAX^® GEMM^® Strains.

Mating System Ovarian Transplant-Cross-Intercross (Female x Male)
TJL Breeding Scheme: ovarian transplant recipient from homozygote x B6C3FeF1 a/a (001022) then obligate heterozygote x heterozygote

Species laboratory mouse

H2 Haplotype k/b segregating

Generation N49F1 (14-DEC-07)

Appearance
black (may have white belly spot), circling, ataxic, short tail
Related Genotype: a/a Lmx1a^dr-J/Lmx1a^dr-J

black, unaffected
Related Genotype: a/a Lmx1a^dr-J/+ or a/a ?/+
Strain Description
Lmx1a encodes a LIM homeodomain (LIM-hd) protein that is expressed in the roof plate along the neuraxis during CNS development. The Lmx1a^dr-J mutation replaces a conserved cysteine in the LIM1 domain of the protein with a tyrosine (Millonig et al. 2000).
Mice homozygous for Lmx1a^dr-Jare identifiable at birth by a thin filament extending from the end of the tail, which drops off within a few days, and a short or blunt tail. They may also have a head bleb. When fur develops, there may be a white belly spot. Lmx1a^dr-J/Lmx1a^dr-J mice are ataxic and hyperactive and have difficulty righting themselves, and they do not reproduce (Sweet and Wahlsten 1983). They also exhibit circling behavior, are deaf, and have inner ear and vertebral malformations (Manzanares et al. 2000).
Lmx1a^dr-J homozygotes exhibit defects of three classes of anatomic structures: the hindbrain roof plate, neural crest derived tissues, and the axial skeleton. Failure of roofplate development results in absence of dorsal interneurons of the spinal cord and of granule neurons of the cerebellar cortex and failure of the dorsal vertebral neural arches to form (Millonig et al. 2000). The cerebellum is smaller than normal, in some cases virtually absent, and exhibits disrupted foliation (Sweet and Wahlsten 1983; Sekiguchi et al. 1992). The cytoarchitectural organization of the neocortex, the hippocampus and the dentate gyrus is disrupted (Sekiguchi et al. 1992, 1993, 1994, 1996). Skeletal anomalies include abnormal neural crest derived cranial bones and improper fusion of cervical and thoracic vertebrae at the dorsal midline (Mananares et al. 2000). Deafness may be the consequence of "serious morphogenetic defects of the otic vesicle due to the dorsal neural tube abnormalities," perhaps augmented by "abnormal sensory and motor projections" in the region of rhombomeres 4-6 (Manzanares et al. 2000). Although they have no external or behavioral phenotype, 50% of heterozygotes exhibit histological pathology of the hippocampus qualitatively similar, but less extensive, than that of homozygotes (Patrylo et al. 1990).
Strain Development
The Lmx1a^dr-J mutation, originally called sst^J and later known as dr^sst-J and as dr^J, arose in the C3FeB6-A/A^w-J-ank colony in the Mouse Mutant Stocks Center at The Jackson Laboratory (Sweet and Wahlsten 1983). Since its discovery, it has been maintained by crossing ovary transplant recipients to B6C3Fe-a/a males; the black coat color of the present background makes it easy to distinguish pups derived from the transplanted ovary from any that might result from residual host ovarian tissue. Identification of the alleles for markers flanking Lmx1a in Lmx1a^dr-J/Lmx1a^dr-J progeny of B6C3Fe a/a-Lmx1a^dr-J/J pairs demonstrated that the mutation occurred on the C3H chromosome (Millonig et al. 2000).

Mammalian Phenotype Terms assigned by genotype

Lmx1a^dr-J/Lmx1a⁺
B6.Cg-Lmx1a^dr-J
pigmentation phenotype

belly spot (MGI Ref ID J:63181)

in C57BL/6 background, a white patch of variable size in the coat on the belly

in C57BL/6 background, white spotting trait became fully penetrant

skin/coat/nails phenotype

belly spot (MGI Ref ID J:63181)

in C57BL/6 background, a white patch of variable size in the coat on the belly

in C57BL/6 background, white spotting trait became fully penetrant

Lmx1a^dr-J/Lmx1a^dr-J
B6.Cg-Lmx1a^dr-J
lethality-postnatal

postnatal lethality (MGI Ref ID J:63181)

shorter life span than wild type in original mixed background

in C57BL/6 background, no live homozygotes are generated

Lmx1a^dr-J/Lmx1a^dr-J
involves: C3H * C57BL/6
behavior/neurological phenotype

circling (MGI Ref ID J:63181)

head tossing (MGI Ref ID J:63181)

hearing/vestibular/ear phenotype

circling (MGI Ref ID J:63181)

deafness (MGI Ref ID J:63181)

head tossing (MGI Ref ID J:63181)

pigmentation phenotype

belly spot (MGI Ref ID J:63181)

a complete white belt around trunk with some variability

skin/coat/nails phenotype

belly spot (MGI Ref ID J:63181)

a complete white belt around trunk with some variability

lethality-postnatal

postnatal lethality (MGI Ref ID J:63181)

shorter life span than wild type in original mixed back ground

initial breeding experiments in mixed back ground generated many live born homozygous pups

nervous system phenotype

abnormal glossopharyngeal ganglion morphology (MGI Ref ID J:63181)

much reduced glossopharyngeal ganglion

abnormal glossopharyngeal nerve morphology (MGI Ref ID J:63181)

an accessory branch originating in the glossopharyngeal/vagus region projects abnormally

abnormal rhombomere morphology (MGI Ref ID J:63181)

significant changes in the shape of rhombomeres 3, 4, and 5 are observed in homozygote embryos

however, hindbrain segmentation is not affected

abnormal roof plate morphology (MGI Ref ID J:63181)

defective roof plate formation in the hindbrain

spina bifida (MGI Ref ID J:63181)

in vertebrae T9-T13

craniofacial phenotype

abnormal interparietal bone morphology (MGI Ref ID J:63181)

the shape and ossification is severely disrupted

abnormal parietal bone morphology (MGI Ref ID J:63181)

the shape of the parietal bone is affected

highly disorganized lamboid suture

skeleton phenotype

abnormal interparietal bone morphology (MGI Ref ID J:63181)

the shape and ossification is severely disrupted

abnormal parietal bone morphology (MGI Ref ID J:63181)

the shape of the parietal bone is affected

highly disorganized lamboid suture

abnormal vertebral arch development (MGI Ref ID J:63181)

neural arches in C1 fail to form along the dorsal midline

delay in fusion of the arches in C2 and C3

failure in dorsal fusion of vertebrae T9-T13 causing grossly altered neural arches

synostosis (MGI Ref ID J:63181)

occasional synostosis of the cranial vault along the interface of the interparietal and supraoccipital bone

responsible for the blebbing on the head seen in live animals

Lmx1a^dr-J/Lmx1a^dr-J
C3FeB6 A/A^w-J-Ank^ank Lmx1a^dr-J
limbs/digits/tail phenotype

short tail (MGI Ref ID J:13949)

a tiny filament at the tip of the tail seen at birth disappears by 2 days after birth leaving either a short tail or distinctly blunted tail

nervous system phenotype

abnormal cerebellar foliation (MGI Ref ID J:13949)

small cerebellum (MGI Ref ID J:13949)

behavior/neurological phenotype

altered righting response (MGI Ref ID J:13949)

a delayed development of the righting reflex

hyperactivity (MGI Ref ID J:13949)

pigmentation phenotype

belly spot (MGI Ref ID J:13949)

white belly spot and feet

skin/coat/nails phenotype

belly spot (MGI Ref ID J:13949)

white belly spot and feet

lethality-postnatal

postnatal lethality (MGI Ref ID J:13949)

preweaning mortality is high

reproductive system phenotype

infertility (MGI Ref ID J:13949)

Gene & Allele Details

Allele Symbol		Lmx1a^dr-J
Allele Name		dreher Jackson
Common Name(s)		sst^J;
Strain of Origin		C3FeB6 A/A^w-J-Ank^ank/J
Gene Symbol and Name		Lmx1a, LIM homeobox transcription factor 1 alpha
Chromosome		1
Gene Common Name(s)		LMX-1; LMX1; LMX1.1; MGC87616; dr; dreher; shaker short-tail; sst;
General Note		Abnormalities of cytoarchitectonics have been studied in the hippocampus and cerebellum of dr^J/dr^J mice (J:1460). An abnormal distribution of acetylcholinesterase accompanies the cytoarchitectonic abnormalities (J:14476). A disruption of neuronal migration may lie behind these abnormal conditions (J:17085).
Molecular Note		A G-to-A transition mutation results in a conserved cysteine to a tyrosine amino acid change in the LIM1 domain of the encoded protein. The conserved cysteine is thought to be required for coordination of zinc that is essential for the function of the LIM domain, and thus the transcriptional activity of the protein. [MGI Ref ID J:60593]

Allele Symbol		a
Allele Name		nonagouti

Control Information

Allele	Control
Lmx1a^dr-J	Untyped from the colony

Considerations for Choosing Controls
Control Pricing Information for JAX^® GEMM^® Strains

Related Strains

Strains carrying a allele

003879 B10;TFLe-a/a T tf/+ tf/J

001538 B6 x B6C3Sn a/A-T(1;9)27H/J

000916 B6 x B6C3Sn a/A-T(5;12)31H/J

000602 B6 x B6C3Sn a/A-T(8;16)17H/J

000618 B6 x FSB/GnEi a/a Ctsl^fs/J

000577 B6 x STOCK a Oca2^p Hps5^ru2 Ednrb^s/J

000601 B6 x STOCK a/a T(7;18)50H/J

000592 B6 x STOCK T(2;4)13H a/J

000001 B6.C3 A/a Mgrn1^md/J

000785 B6;D2-a Es1^e/J

000604 B6C3 a/A-T(10;13)199H +/+ Lyst^bg-J/J or Lyst^bg-2J/J

002807 B6C3Fe a/a-Meox2^fla/J

000224 B6C3Fe a/a-Scyl1^mdf/J

001037 B6C3Fe a/a-Agtpbp1^pcd/J

000221 B6C3Fe a/a-Alx4^lst-J/J

002062 B6C3Fe a/a-Atp7a^Mo-8J/J

001756 B6C3Fe a/a-Cacng2^stg/J

001815 B6C3Fe a/a-Col1a2^oim/J

000231 B6C3Fe a/a-Csf1^op/J

000209 B6C3Fe a/a-Dh/J

000211 B6C3Fe a/a-Dst^dt-J/J

000210 B6C3Fe a/a-Edar^dl-J/J

000207 B6C3Fe a/a-Edaradd^cr/J

000182 B6C3Fe a/a-Eef1a2^wst/J

001278 B6C3Fe a/a-Glra1^spd/J

000241 B6C3Fe a/a-Glrb^spa/J

002875 B6C3Fe a/a-Hoxd13^spdh/J

000304 B6C3Fe a/a-Krt71^Ca Scn8a^med-J/J

000226 B6C3Fe a/a-Large^myd/J

001280 B6C3Fe a/a-Lse/J

001573 B6C3Fe a/a-Mitf^Mi/J

001035 B6C3Fe a/a-Napa^hyh/J

000181 B6C3Fe a/a-Otog^twt/J

000278 B6C3Fe a/a-Papss2^bm Hps1^ep Hps6^ru/J

000205 B6C3Fe a/a-Papss2^bm/J

002078 B6C3Fe a/a-Pcdh15^av-2J/J

000246 B6C3Fe a/a-Pitpna^vb/J

001430 B6C3Fe a/a-Ptch1^mes/J

000506 B6C3Fe a/a-Qk^qk/J

000235 B6C3Fe a/a-Reln^rl/J

000237 B6C3Fe a/a-Rora^sg/J

000290 B6C3Fe a/a-Sox10^Dom/J

000230 B6C3Fe a/a-Tcirg1^oc/J

003612 B6C3Fe a/a-Trak1^hyrt/J

001512 B6C3Fe a/a-Ttn^mdm/J

001607 B6C3Fe a/a-Unc5c^rcm/J

000005 B6C3Fe a/a-Wc/J

000243 B6C3Fe a/a-Wnt1^sw/J

000248 B6C3Fe a/a-Xpl/J

001750 B6C3Fe a/a-Xs^J/J

000624 B6C3Fe a/a-anx/J

003020 B6C3Fe a/a-dep/J

002018 B6C3Fe a/a-din/J

002339 B6C3Fe a/a-nma/J

000240 B6C3Fe a/a-soc/J

000063 B6C3Fe a/a-sy/J

001055 B6C3Fe a/a-tip/J

000245 B6C3Fe a/a-tn/J

000296 B6C3Fe-a/a Hoxa13^Hd Mcoln3^Va-J/J

000019 B6C3Fe-a/a-Itpr1^opt/J

001022 B6C3FeF1/J a/a

000971 B6EiC3 a/A-Och/J

000551 B6EiC3 a/A-Tbx15^de-H/J

006450 B6EiC3 a/A-Vss/J

000557 B6EiC3-+ a/Lnp^Ul A/J

000503 B6EiC3Sn a/A-Gy/J

001811 B6EiC3Sn a/A-Otc^spf-ash/J

002343 B6EiC3Sn a/A-Otc^spf/J

000391 B6EiC3Sn a/A-Pax6^Sey-Dey/J

001924 B6EiC3Sn a/A-Ts(17¹⁶)65Dn

001923 B6EiC3Sn a/A-Ts(4¹⁷)2Lws Tim/J

000225 C3FeLe.B6 a/a-Ptpn6^me/J

000198 C3FeLe.B6-a/J

000291 C3FeLe.Cg-a/a Hm Kitl^Sl Krt71^Ca-J/J

001886 C3HeB/FeJLe a/a-gnd/J

000584 C57BL/6J-+ T(1;2)5Ca/a +/J

000284 CWD/LeJ

000670 DBA/1J

000671 DBA/2J

001057 HPT/LeJ

000260 JGBF/LeJ

000265 MY/HuLeJ

000308 SSL/LeJ

000994 STOCK a Myo5a^d Mreg^dsu/J

000064 STOCK a Tyrp1^b Si^si/J

002238 STOCK a Tyrp1^b shmy/J

001433 STOCK a skt/J

000579 STOCK a tp/J

000319 STOCK a us/J

002648 STOCK a/a Cln6^nclf/J

000317 STOCK a/a Egfr^wa2/J

000302 STOCK a/a Mitf^Mi-wh +/+ Itpr1^opt/J

000286 STOCK a/a Myo5a^d fd/+ +/J

000206 STOCK a/a Tyr^c-h/J

001432 STOCK a/a Tyrp1^b sks/Tyrp1^b +/J

000281 STOCK a/a ma ft/ma ft/J

000312 STOCK stb + a/+ Fign^fi a/J

000596 STOCK T(2;11)30H/+ x AEJ-a Gdf5^bp-H/J or A/J-a Gdf5^bp-J/J

000970 STOCK T(2;16)28H A/T(2;16)28H a/J

000590 STOCK T(2;4)1Sn a/J

000594 STOCK T(2;8)26H a/T(2;8)26H a Tyrp1⁺/Tyrp1^b/J

000623 TR/DiEiJ

View Strains carrying a (102 strains)

Strains carrying other alleles of Lmx1a

004202 B6.C3 Pde6b^rd1 Hps4^le/+ +-Lmx1a^dr-8J/J

002624 B6.C3-Lmx1a^dr-6J/J

View Strains carrying other alleles of Lmx1a (2 strains)

Strains carrying other alleles of a

003301 (C57BL/6J x C3H-Eya1^bor)F1/J

000251 AEJ.Cg-a^e +/a Gdf5^bp-H/J

000202 AEJ/Gn-bd/J

000199 AEJ/GnLeJ

000427 B10.CE-H13^b A^w/(30NX)SnJ

000420 B10.LP-H13^b A^w/Sn

000477 B10.PA-Pldn^pa H3^e a^t/SnJ

000419 B10.UW-H3^b we Pax1^un a^t/SnJ

000593 B6 x B6CBCa A^w-J/A-Grid2^Lc T(2;6)7Ca Mitf^Mi-wh/J

000502 B6 x B6CBCa A^w-J/A-Myo5a^flr Gnb5^flr/J

000599 B6 x B6CBCa A^w-J/A-T(5;13)264Ca Kit^W-v/J

002083 B6 x B6EiC3 a/A-T(7;16)235Dn/J

000507 B6 x B6EiC3 a/A-Otc^spf/J

002016 B6(Cg)-A^w-J Eda^Ta-6J Chr Y^B6-Sxr/EiJ

000552 B6-A^w-J-Eda^Ta-6J.Cg-Sxr

001730 B6-A^w-J-Eda^Ta-6J.Cg-Sxr^b Hya^-/J

000841 B6-A^w-J.CBy-Eda^Ta-By/J

001809 B6-A^w-J.Cg-Eda^Ta-6J +/+ Ar^Tfm/J

000600 B6-Gpi1^b x B6CBCa A^w-J/A-T(7;15)9H Gpi1^a/J

000769 B6.C/(HZ18)By-a^t-44J/J

000203 B6.C3-A^iy/a/J

000017 B6.C3Fe-A^vy/J

000628 B6.CE-A Amy1^b Amy2^b/J

005505 B6.Cg-A^y Slc7a11^sut/LmLlp

000021 B6.Cg-A^y/J

001572 B6.Cg-a^m-J/J

100409 B6129PF1/J-A^w-J/A^w

004200 B6;CBACa A^w-J/A-Npr2^cn-2J/J

000505 B6C3 A^w-J/A-Muted^mu/J

000604 B6C3 a/A-T(10;13)199H +/+ Lyst^bg-J/J or Lyst^bg-2J/J

000065 B6C3Fe a/a-we Pax1^un a^t/J

000314 B6CBACa A^w-J/A-Eda^Ta/J-XO

000501 B6CBACa A^w-J/A-Aifm1^Hq/J

001046 B6CBACa A^w-J/A-Grid2^Lc/J

000500 B6CBACa A^w-J/A-Gs/J

002703 B6CBACa A^w-J/A-Hydin^hy3/J

000247 B6CBACa A^w-J/A-Kcnj6^wv/J

000287 B6CBACa A^w-J/A-Plp1^jp Eda^Ta/J

000515 B6CBACa A^w-J/A-Sfn^Er/J

000242 B6CBACa A^w-J/A-spc/J

000288 B6CBACa A^w-J/A-we a Mafb^kr/J

001201 B6CBACaF1/J-A^w-J/A

001752 B6CBCa A^w-J/A-T(7;15)9H/J

006450 B6EiC3 a/A-Vss/J

000557 B6EiC3-+ a/Lnp^Ul A/J

000504 B6EiC3Sn a/A-Cacnb4^lh/J

000553 B6EiC3Sn a/A-Egfr^wa2 Wnt3a^vt/J

001811 B6EiC3Sn a/A-Otc^spf-ash/J

002343 B6EiC3Sn a/A-Otc^spf/J

001923 B6EiC3Sn a/A-Ts(4¹⁷)2Lws Tim/J

000200 C3FeB6 A/A^w-J-Ank^ank/J

000638 C3FeB6 A/A^w-J-Spnb4^qv-J/J

001203 C3FeB6F1/J A/A^w-J

001272 C3H/HeSnJ-A^hvy/J

000099 C3HeB/FeJ-A^vy/J

000338 C57BL/6J A^w-J-Eda^Ta-6J/J

000258 C57BL/6J-Aⁱ/a/J

000774 C57BL/6J-A^sy/a/J

000569 C57BL/6J-A^w-J-Eda^Ta +/+ Ar^Tfm/J

000051 C57BL/6J-A^w-J/J

000055 C57BL/6J-a^t-33J/J

000070 C57BL/6J-a^td/J

002468 KK.Cg-A^y/J

000262 LS/LeJ

000283 LT.CAST-A/J

001759 STOCK A Tyr^c Sha/J

001427 STOCK A^w us/J

View Strains carrying other alleles of a (67 strains)

Animal Health Reports

Room Number FGB29

Research Applications

This mouse can be used to support research in many areas including:

Lmx1a^dr-J related

Developmental Biology Research
Craniofacial and Palate Defects
Neural Tube Defects

Neurobiology Research
Cerebellar Defects
Neural Tube Defects
Vestibular and Hearing Defects

Sensorineural Research
Vestibular and Hearing Defects

References

Additional References

Price and Supply Information

Strain Name:	*B6C3Fe a/a-Lmx1a^dr-J/J*
Stock Number:	000636

Price Details

IMPORTANT NOTE: Prices are based on shipping destination. The shipping destinations are:

USA, Canada and Mexico
International

*Pricing for Shipping Destination selected:

USA, Canada and Mexico

Price(s) in US dollars ($)		Genotype(s) Provided
Individual Mouse Price	$203.30	Homozygous for Lmx1a^dr-J
Pair	$256.40	Heterozygous for Lmx1a^dr-J x Heterozygous for Lmx1a^dr-J

Supply Details

Standard Supply	Repository-Live. A collection of over 1000 strains maintained as live colonies. Individual colonies are sized to meet current customer demand. Delivery for orders of 10 mice or less ranges on average from one to eight weeks; mice are generally shipped between four to six weeks of age with a maximum shipping age of ~nine weeks. Colony sizes do not generally support stringent age specifications for large volumes of mice; however custom orders and larger quantities of mice are easily arranged. Estimated ship dates for all orders provided within 48 hours of order placement.
Supply Notes	Histology and Tissue Collection Services are available for all JAX^® Mice strains. For more information, please contact Customer Service at orderquest@jax.org or 1-800-422-6423. Usually shipped between four and eight weeks of age. This strain is included in the Mouse Mutant Resource collection. Genomic DNA is available for this strain from the Mouse DNA Resource.
Licensing	See General Terms and Conditions below
Control Information	View Control Information in Strain Details. View Control Pricing Information for JAX^® Strains.

General Terms and Conditions

View JAX^® Mice & Services Conditions of Use.

The Jackson Laboratory's Genotype Promise

The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX^® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX^® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX^® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.

Ordering and Purchasing Information

Purchasing Information
JAX^® Mice Orders
Surgical Services

Contact Information
Orders & Technical Support
Tel: 800.422.6423 or 207.288.5845
Fax: 207.288.6150
Technical Support Email Form

Go to JAX^® Mice Query Form

003879	B10;TFLe-a/a T tf/+ tf/J
001538	B6 x B6C3Sn a/A-T(1;9)27H/J
000916	B6 x B6C3Sn a/A-T(5;12)31H/J
000602	B6 x B6C3Sn a/A-T(8;16)17H/J
000618	B6 x FSB/GnEi a/a Ctsl^fs/J
000577	B6 x STOCK a Oca2^p Hps5^ru2 Ednrb^s/J
000601	B6 x STOCK a/a T(7;18)50H/J
000592	B6 x STOCK T(2;4)13H a/J
000001	B6.C3 A/a Mgrn1^md/J
000785	B6;D2-a Es1^e/J
000604	B6C3 a/A-T(10;13)199H +/+ Lyst^bg-J/J or Lyst^bg-2J/J
002807	B6C3Fe a/a-Meox2^fla/J
000224	B6C3Fe a/a-Scyl1^mdf/J
001037	B6C3Fe a/a-Agtpbp1^pcd/J
000221	B6C3Fe a/a-Alx4^lst-J/J
002062	B6C3Fe a/a-Atp7a^Mo-8J/J
001756	B6C3Fe a/a-Cacng2^stg/J
001815	B6C3Fe a/a-Col1a2^oim/J
000231	B6C3Fe a/a-Csf1^op/J
000209	B6C3Fe a/a-Dh/J
000211	B6C3Fe a/a-Dst^dt-J/J
000210	B6C3Fe a/a-Edar^dl-J/J
000207	B6C3Fe a/a-Edaradd^cr/J
000182	B6C3Fe a/a-Eef1a2^wst/J
001278	B6C3Fe a/a-Glra1^spd/J
000241	B6C3Fe a/a-Glrb^spa/J
002875	B6C3Fe a/a-Hoxd13^spdh/J
000304	B6C3Fe a/a-Krt71^Ca Scn8a^med-J/J
000226	B6C3Fe a/a-Large^myd/J
001280	B6C3Fe a/a-Lse/J
001573	B6C3Fe a/a-Mitf^Mi/J
001035	B6C3Fe a/a-Napa^hyh/J
000181	B6C3Fe a/a-Otog^twt/J
000278	B6C3Fe a/a-Papss2^bm Hps1^ep Hps6^ru/J
000205	B6C3Fe a/a-Papss2^bm/J
002078	B6C3Fe a/a-Pcdh15^av-2J/J
000246	B6C3Fe a/a-Pitpna^vb/J
001430	B6C3Fe a/a-Ptch1^mes/J
000506	B6C3Fe a/a-Qk^qk/J
000235	B6C3Fe a/a-Reln^rl/J
000237	B6C3Fe a/a-Rora^sg/J
000290	B6C3Fe a/a-Sox10^Dom/J
000230	B6C3Fe a/a-Tcirg1^oc/J
003612	B6C3Fe a/a-Trak1^hyrt/J
001512	B6C3Fe a/a-Ttn^mdm/J
001607	B6C3Fe a/a-Unc5c^rcm/J
000005	B6C3Fe a/a-Wc/J
000243	B6C3Fe a/a-Wnt1^sw/J
000248	B6C3Fe a/a-Xpl/J
001750	B6C3Fe a/a-Xs^J/J
000624	B6C3Fe a/a-anx/J
003020	B6C3Fe a/a-dep/J
002018	B6C3Fe a/a-din/J
002339	B6C3Fe a/a-nma/J
000240	B6C3Fe a/a-soc/J
000063	B6C3Fe a/a-sy/J
001055	B6C3Fe a/a-tip/J
000245	B6C3Fe a/a-tn/J
000296	B6C3Fe-a/a Hoxa13^Hd Mcoln3^Va-J/J
000019	B6C3Fe-a/a-Itpr1^opt/J
001022	B6C3FeF1/J a/a
000971	B6EiC3 a/A-Och/J
000551	B6EiC3 a/A-Tbx15^de-H/J
006450	B6EiC3 a/A-Vss/J
000557	B6EiC3-+ a/Lnp^Ul A/J
000503	B6EiC3Sn a/A-Gy/J
001811	B6EiC3Sn a/A-Otc^spf-ash/J
002343	B6EiC3Sn a/A-Otc^spf/J
000391	B6EiC3Sn a/A-Pax6^Sey-Dey/J
001924	B6EiC3Sn a/A-Ts(17¹⁶)65Dn
001923	B6EiC3Sn a/A-Ts(4¹⁷)2Lws Tim/J
000225	C3FeLe.B6 a/a-Ptpn6^me/J
000198	C3FeLe.B6-a/J
000291	C3FeLe.Cg-a/a Hm Kitl^Sl Krt71^Ca-J/J
001886	C3HeB/FeJLe a/a-gnd/J
000584	C57BL/6J-+ T(1;2)5Ca/a +/J
000284	CWD/LeJ
000670	DBA/1J
000671	DBA/2J
001057	HPT/LeJ
000260	JGBF/LeJ
000265	MY/HuLeJ
000308	SSL/LeJ
000994	STOCK a Myo5a^d Mreg^dsu/J
000064	STOCK a Tyrp1^b Si^si/J
002238	STOCK a Tyrp1^b shmy/J
001433	STOCK a skt/J
000579	STOCK a tp/J
000319	STOCK a us/J
002648	STOCK a/a Cln6^nclf/J
000317	STOCK a/a Egfr^wa2/J
000302	STOCK a/a Mitf^Mi-wh +/+ Itpr1^opt/J
000286	STOCK a/a Myo5a^d fd/+ +/J
000206	STOCK a/a Tyr^c-h/J
001432	STOCK a/a Tyrp1^b sks/Tyrp1^b +/J
000281	STOCK a/a ma ft/ma ft/J
000312	STOCK stb + a/+ Fign^fi a/J
000596	STOCK T(2;11)30H/+ x AEJ-a Gdf5^bp-H/J or A/J-a Gdf5^bp-J/J
000970	STOCK T(2;16)28H A/T(2;16)28H a/J
000590	STOCK T(2;4)1Sn a/J
000594	STOCK T(2;8)26H a/T(2;8)26H a Tyrp1⁺/Tyrp1^b/J
000623	TR/DiEiJ

004202	B6.C3 Pde6b^rd1 Hps4^le/+ +-Lmx1a^dr-8J/J
002624	B6.C3-Lmx1a^dr-6J/J

003301	(C57BL/6J x C3H-Eya1^bor)F1/J
000251	AEJ.Cg-a^e +/a Gdf5^bp-H/J
000202	AEJ/Gn-bd/J
000199	AEJ/GnLeJ
000427	B10.CE-H13^b A^w/(30NX)SnJ
000420	B10.LP-H13^b A^w/Sn
000477	B10.PA-Pldn^pa H3^e a^t/SnJ
000419	B10.UW-H3^b we Pax1^un a^t/SnJ
000593	B6 x B6CBCa A^w-J/A-Grid2^Lc T(2;6)7Ca Mitf^Mi-wh/J
000502	B6 x B6CBCa A^w-J/A-Myo5a^flr Gnb5^flr/J
000599	B6 x B6CBCa A^w-J/A-T(5;13)264Ca Kit^W-v/J
002083	B6 x B6EiC3 a/A-T(7;16)235Dn/J
000507	B6 x B6EiC3 a/A-Otc^spf/J
002016	B6(Cg)-A^w-J Eda^Ta-6J Chr Y^B6-Sxr/EiJ
000552	B6-A^w-J-Eda^Ta-6J.Cg-Sxr
001730	B6-A^w-J-Eda^Ta-6J.Cg-Sxr^b Hya^-/J
000841	B6-A^w-J.CBy-Eda^Ta-By/J
001809	B6-A^w-J.Cg-Eda^Ta-6J +/+ Ar^Tfm/J
000600	B6-Gpi1^b x B6CBCa A^w-J/A-T(7;15)9H Gpi1^a/J
000769	B6.C/(HZ18)By-a^t-44J/J
000203	B6.C3-A^iy/a/J
000017	B6.C3Fe-A^vy/J
000628	B6.CE-A Amy1^b Amy2^b/J
005505	B6.Cg-A^y Slc7a11^sut/LmLlp
000021	B6.Cg-A^y/J
001572	B6.Cg-a^m-J/J
100409	B6129PF1/J-A^w-J/A^w
004200	B6;CBACa A^w-J/A-Npr2^cn-2J/J
000505	B6C3 A^w-J/A-Muted^mu/J
000604	B6C3 a/A-T(10;13)199H +/+ Lyst^bg-J/J or Lyst^bg-2J/J
000065	B6C3Fe a/a-we Pax1^un a^t/J
000314	B6CBACa A^w-J/A-Eda^Ta/J-XO
000501	B6CBACa A^w-J/A-Aifm1^Hq/J
001046	B6CBACa A^w-J/A-Grid2^Lc/J
000500	B6CBACa A^w-J/A-Gs/J
002703	B6CBACa A^w-J/A-Hydin^hy3/J
000247	B6CBACa A^w-J/A-Kcnj6^wv/J
000287	B6CBACa A^w-J/A-Plp1^jp Eda^Ta/J
000515	B6CBACa A^w-J/A-Sfn^Er/J
000242	B6CBACa A^w-J/A-spc/J
000288	B6CBACa A^w-J/A-we a Mafb^kr/J
001201	B6CBACaF1/J-A^w-J/A
001752	B6CBCa A^w-J/A-T(7;15)9H/J
006450	B6EiC3 a/A-Vss/J
000557	B6EiC3-+ a/Lnp^Ul A/J
000504	B6EiC3Sn a/A-Cacnb4^lh/J
000553	B6EiC3Sn a/A-Egfr^wa2 Wnt3a^vt/J
001811	B6EiC3Sn a/A-Otc^spf-ash/J
002343	B6EiC3Sn a/A-Otc^spf/J
001923	B6EiC3Sn a/A-Ts(4¹⁷)2Lws Tim/J
000200	C3FeB6 A/A^w-J-Ank^ank/J
000638	C3FeB6 A/A^w-J-Spnb4^qv-J/J
001203	C3FeB6F1/J A/A^w-J
001272	C3H/HeSnJ-A^hvy/J
000099	C3HeB/FeJ-A^vy/J
000338	C57BL/6J A^w-J-Eda^Ta-6J/J
000258	C57BL/6J-Aⁱ/a/J
000774	C57BL/6J-A^sy/a/J
000569	C57BL/6J-A^w-J-Eda^Ta +/+ Ar^Tfm/J
000051	C57BL/6J-A^w-J/J
000055	C57BL/6J-a^t-33J/J
000070	C57BL/6J-a^td/J
002468	KK.Cg-A^y/J
000262	LS/LeJ
000283	LT.CAST-A/J
001759	STOCK A Tyr^c Sha/J
001427	STOCK A^w us/J

Strain Name:

B6C3Fe a/a-Lmx1adr-J/J

Stock Number:

000636

Availability:

Repository- Live

Price and Supply Information

General Terms and Conditions

Product Information

Strain Details

Lmx1adr-J/Lmx1a+

Lmx1adr-J/Lmx1adr-J

Lmx1adr-J/Lmx1adr-J

Lmx1adr-J/Lmx1adr-J

Gene & Allele Details

Control Information

Related Strains

Animal Health Reports

Research Applications

References

Price and Supply Information

Price Details

*Pricing for Shipping Destination selected:

USA, Canada and Mexico

Supply Details

General Terms and Conditions

The Jackson Laboratory's Genotype Promise

B6C3Fe a/a-Lmx1a^dr-J/J

Lmx1a^dr-J/Lmx1a⁺

Lmx1a^dr-J/Lmx1a^dr-J

Lmx1a^dr-J/Lmx1a^dr-J

Lmx1a^dr-J/Lmx1a^dr-J