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Type Inbred Strain; Additional information on Inbred Strains. Visit our online Nomenclature tutorial. Mating System Sibling x Sibling (Female x Male) 01-MAR-06 Species laboratory mouse H2 Haplotype b Generation F239 (03-JAN-08)
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black
Related Genotype: a/aDescription
C57BL/10J is a substrain of C57BL, and shares a common origin with C57BL/6J (Stock No. 000664), which is one of the most widely used inbred strains. Coat color is black (non-agouti), a/a. The C57BL/10J substrain is similar to the C57BL/6J substrain, but allelic variants have been described at the H9, Igh2 and Lv loci. C57BL/10J mice have a long life-span (826 +/-29 days in males, 693 +/- 31 days in females). Overall tumor incidence is 33% in males and 31% in females, most of which is due to lymphoma. C57BL/10J mice are prone to dermatitis, which is a common problem in the C57BL strain. C57BL/10J mice are a valuable immunological research tool. They have a high lymphocyte phytohaemagglutinin response, a good immune response to ovalbumin, a poor response to DNP-keyhole limpet haemocyanin and are resistant to induction of passive cutaneous anaphylaxis (IgG1- and IgE- mediated). They are susceptible to immunosuppression of contact hypersensitivity by ultraviolet light, highly susceptible to TNBS-induced colitis and moderately susceptible to experimental allergic encephalomyelitis.
C57BL Strains
003752 C57BL/10ScNJ 000476 C57BL/10ScSnJ 000666 C57BL/10SnJ 001822 C57BL/10SxJ 001197 C57BL/10WtRkJ 000663 C57BL/6By 001139 C57BL/6ByJ 009123 C57BL/6HaJ 000664 C57BL/6J 000924 C57BL/6JEiJ 005304 C57BL/6NJ View C57BL Strains (11 strains)
Genetic Quality Control Annual Report
JAX® NOTES, April 1988; 433. H-2 Haplotypes of Mice from Jackson Laboratory Production Colonies.
JAX® NOTES, Fall 1995; 463. Inbred C57 Black Mice: Microphthalmia and Ocular Infections.
View Phenotypic Data
Phenotypic Data
Mouse Phenome Database
Festing Inbred Strain Characteristics: C57BL
View Research Applications
Research Applications
This mouse can be used to support research in many areas including:
Research Tools
General Purpose
Immunology and Inflammation Research
background strain for histocompatibility congenics
Inbred mouse strains are maintained through sibling (sister x brother) matings; no genotyping required.
Genotyping resources and troubleshooting
Fichtner-Feigl S; Fuss IJ; Preiss JC; Strober W; Kitani A. 2005. Treatment of murine Th1- and Th2-mediated inflammatory bowel disease with NF-kappa B decoy oligonucleotides. J Clin Invest 115(11):3057-71. [PubMed: 16239967] [MGI Ref ID J:145688]
Animal Health Reports
Room Number AX9
Colony Maintenance
Mating System Sibling x Sibling (Female x Male) 01-MAR-06 Diet Information LabDiet® 5K52/5K67
| Pricing for USA, Canada and Mexico shipping destinations |
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Weeks of Age Price (US dollars $) Gender 3-5 weeks $17.65 Female $18.30 Male 6 weeks $19.70 Female $20.35 Male 7 weeks $21.75 Female $22.40 Male 8 weeks $23.80 Female $24.45 Male 9 weeks $25.85 Female $26.50 Male 10 weeks $27.90 Female $28.55 Male 11 weeks $29.95 Female $30.60 Male 12 weeks $32.00 Female $32.65 Male 13 weeks $34.05 Female $34.70 Male 14 weeks $36.10 Female $36.75 Male 15 weeks $38.15 Female $38.80 Male
| Pricing for International shipping destinations |
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Weeks of Age Price (US dollars $) Gender 3-5 weeks $23.00 Female $23.80 Male 6 weeks $25.70 Female $26.50 Male 7 weeks $28.40 Female $29.20 Male 8 weeks $31.10 Female $31.90 Male 9 weeks $33.80 Female $34.60 Male 10 weeks $36.50 Female $37.30 Male 11 weeks $39.20 Female $40.00 Male 12 weeks $41.90 Female $42.70 Male 13 weeks $44.60 Female $45.40 Male 14 weeks $47.30 Female $48.10 Male 15 weeks $50.00 Female $50.80 Male
| Standard Supply | Level 2. Up to 100 mice. Larger quantities or custom orders arranged upon request. |
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| Supply Notes |
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Purchasing Information
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