Additional References

Aberg KM; Man MQ; Gallo RL; Ganz T; Crumrine D; Brown BE; Choi EH; Kim DK; Schroder JM; Feingold KR; Elias PM. 2008. Co-regulation and interdependence of the mammalian epidermal permeability and antimicrobial barriers. J Invest Dermatol 128(4):917-25. [PubMed: 17943185]  [MGI Ref ID J:135506]

Ahmad W; Panteleyev AA; Christiano AM. 1999. The molecular basis of congenital atrichia in humans and mice: mutations in the hairless gene. J Investig Dermatol Symp Proc 4(3):240-3. [PubMed: 10674375]  [MGI Ref ID J:59939]

Astner S; Wu A; Chen J; Philips N; Rius-Diaz F; Parrado C; Mihm MC; Goukassian DA; Pathak MA; Gonzalez S. 2007. Dietary lutein/zeaxanthin partially reduces photoaging and photocarcinogenesis in chronically UVB-irradiated Skh-1 hairless mice. Skin Pharmacol Physiol 20(6):283-91. [PubMed: 17717424]  [MGI Ref ID J:128747]

Balansky RM; Izzotti A; D'Agostini F; Camoirano A; Bagnasco M; Lubet RA; De Flora S. 2003. Systemic genotoxic effects produced by light, and synergism with cigarette smoke in the respiratory tract of hairless mice. Carcinogenesis 24(9):1525-32. [PubMed: 12844483]  [MGI Ref ID J:85507]

Brooke HC. 1926. Hairless mice J Hered 17:173-74.  [MGI Ref ID J:2405]

COLEMAN DL. 1962. Effect of genic substitution on the incorporation of tyrosine into the melanin of mouse skin. Arch Biochem Biophys 96:562-8. [PubMed: 13880466]  [MGI Ref ID J:12173]

Cachon-Gonzalez MB; Fenner S; Coffin JM; Moran C; Best S; Stoye JP. 1994. Structure and expression of the hairless gene of mice. Proc Natl Acad Sci U S A 91(16):7717-21. [PubMed: 8052649]  [MGI Ref ID J:19624]

Cachon-Gonzalez MB; San-Jose I; Cano A; Vega JA; Garcia N; Freeman T; Schimmang T; Stoye JP. 1999. The hairless gene of the mouse: relationship of phenotypic effects with expression profile and genotype. Dev Dyn 216(2):113-26. [PubMed: 10536052]  [MGI Ref ID J:57947]

Clark EA; Shultz LD; Pollack SB. 1981. Mutations in mice that influence natural killer (NK) cell activity. Immunogenetics 12(5-6):601-13. [PubMed: 6971254]  [MGI Ref ID J:6485]

Copeland NG; Hutchison KW; Jenkins NA. 1983. Excision of the DBA ecotropic provirus in dilute coat-color revertants of mice occurs by homologous recombination involving the viral LTRs. Cell 33(2):379-87. [PubMed: 6305507]  [MGI Ref ID J:7092]

Crew FAE; Mirskaia L. 1931. The character of "hairless" in the mouse J Genet 25:17-24.  [MGI Ref ID J:2409]

DERINGER MK. 1956. The effect of subcutaneous inoculation of 4-o-tolylazo-o-toluidine in strain HR mice. J Natl Cancer Inst 17(4):533-9. [PubMed: 13367821]  [MGI Ref ID J:24688]

Doig J; Anderson C; Lawrence NJ; Selfridge J; Brownstein DG; Melton DW. 2006. Mice with skin-specific DNA repair gene (Ercc1) inactivation are hypersensitive to ultraviolet irradiation-induced skin cancer and show more rapid actinic progression. Oncogene 25(47):6229-38. [PubMed: 16682947]  [MGI Ref ID J:115849]

Dunn TB; Deringer MK. 1968. Reticulum cell neoplasm, type B, or the Hodgkin's-like lesion of the mouse. J Natl Cancer Inst 40(4):771-821. [PubMed: 4869134]  [MGI Ref ID J:2417]

Dwivedi C; Valluri HB; Guan X; Agarwal R. 2006. Chemopreventive effects of alpha-santalol on ultraviolet B radiation-induced skin tumor development in SKH-1 hairless mice. Carcinogenesis 27(9):1917-22. [PubMed: 16679309]  [MGI Ref ID J:113353]

Egberts F; Heinrich M; Jensen JM; Winoto-Morbach S; Pfeiffer S; Wickel M; Schunck M; Steude J; Saftig P; Proksch E; Schutze S. 2004. Cathepsin D is involved in the regulation of transglutaminase 1 and epidermal differentiation. J Cell Sci 117(Pt 11):2295-307. [PubMed: 15126630]  [MGI Ref ID J:89747]

Engle LJ; Kennett RH. 1994. Cloning, analysis, and chromosomal localization of myoxin (MYH12), the human homologue to the mouse dilute gene. Genomics 19(3):407-16. [PubMed: 8188282]  [MGI Ref ID J:16915]

Fraser FC. 1946. The expression and interaction of hereditary factors producing hypotrichosis in the mouse: histology and experimental results. Can J Res 24:10-25.  [MGI Ref ID J:14940]

Gallagher CH; Canfield PJ; Greenoak GE; Reeve VE. 1984. Characterization and histogenesis of tumors in the hairless mouse produced by low-dosage incremental ultraviolet radiation. J Invest Dermatol 83(3):169-74. [PubMed: 6470519]  [MGI Ref ID J:127204]

Gates AH; Arundell FD; Karasek MA. 1969. Hereditary defect of the pilosebaceous unit in a new double mutant mouse. J Invest Dermatol 52(2):115-8. [PubMed: 5774889]  [MGI Ref ID J:126589]

Grobman AB; Charles DR. 1947. Mutant white mice. A new dominant autosomal mutant affecting coat color in Mus musculus. J Hered 38:381-384.  [MGI Ref ID J:13058]

Hachem JP; Houben E; Crumrine D; Man MQ; Schurer N; Roelandt T; Choi EH; Uchida Y; Brown BE; Feingold KR; Elias PM. 2006. Serine Protease Signaling of Epidermal Permeability Barrier Homeostasis. J Invest Dermatol 126(9):2074-2086. [PubMed: 16691196]  [MGI Ref ID J:111734]

Halin C; Fahrngruber H; Meingassner JG; Bold G; Littlewood-Evans A; Stuetz A; Detmar M. 2008. Inhibition of chronic and acute skin inflammation by treatment with a vascular endothelial growth factor receptor tyrosine kinase inhibitor. Am J Pathol 173(1):265-77. [PubMed: 18535184]  [MGI Ref ID J:137380]

Hearing VJ; Phillips P; Lutzner MA. 1973. The fine structure of melanogenesis in coat color mutants of the mouse. J Ultrastruct Res 43(1):88-106. [PubMed: 4634048]  [MGI Ref ID J:5346]

Heiniger HJ; Huebner RJ; Meier H. 1976. Effect of allelic substitutions at the hairless locus on endogenous ecotropic murine leukemia virus titers and leukemogenesis. J Natl Cancer Inst 56(5):1073-4. [PubMed: 186616]  [MGI Ref ID J:5726]

Heston WE. 1963. Genetics of Neoplasia. In: Methodology in Mammalian Genetics. Holden-Day, San Francisco.  [MGI Ref ID J:23470]

Hiai H; Morrissey P; Khiroya R; Schwartz RS. 1977. Selective expression of xenotropic virus in congenic HRS/J (hairless) mice. Nature 270(5634):247-9. [PubMed: 201855]  [MGI Ref ID J:5908]

Hutchison KW; Copeland NG; Jenkins NA. 1984. Dilute-coat-color locus of mice: nucleotide sequence analysis of the d+2J and d+Ha revertant alleles. Mol Cell Biol 4(12):2899-904. [PubMed: 6098826]  [MGI Ref ID J:7751]

Jenkins NA; Copeland NG; Taylor BA; Lee BK. 1981. Dilute (d) coat colour mutation of DBA/2J mice is associated with the site of integration of an ecotropic MuLV genome. Nature 293(5831):370-4. [PubMed: 6268990]  [MGI Ref ID J:6587]

Jenkins NA; Copeland NG; Taylor BA; Lee BK. 1982. Organization, distribution, and stability of endogenous ecotropic murine leukemia virus DNA sequences in chromosomes of Mus musculus. J Virol 43(1):26-36. [PubMed: 6287001]  [MGI Ref ID J:6844]

Jensen JM; Schutze S; Forl M; Kronke M; Proksch E. 1999. Roles for tumor necrosis factor receptor p55 and sphingomyelinase in repairing the cutaneous permeability barrier. J Clin Invest 104(12):1761-70. [PubMed: 10606630]  [MGI Ref ID J:59056]

Johnson DA; Meier H. 1981. Immune responsiveness of HRS/J mice to syngeneic lymphoma cells. J Immunol 127(2):461-4. [PubMed: 6265551]  [MGI Ref ID J:6535]

Jones SM; Johnson KR; Yu H; Erway LC; Alagramam KN; Pollak N; Jones TA. 2005. A quantitative survey of gravity receptor function in mutant mouse strains. J Assoc Res Otolaryngol 6(4):297-310. [PubMed: 16235133]  [MGI Ref ID J:116914]

Kajiya K; Hirakawa S; Detmar M. 2006. Vascular endothelial growth factor-A mediates ultraviolet B-induced impairment of lymphatic vessel function. Am J Pathol 169(4):1496-503. [PubMed: 17003502]  [MGI Ref ID J:113381]

Kato M; Ohgami N; Kawamoto Y; Tsuzuki T; Hossain K; Yanagishita T; Ohshima Y; Tsuboi H; Yamanoshita O; Matsumoto Y; Takahashi M; Nakashima I. 2007. Protective effect of hyperpigmented skin on UV-mediated cutaneous cancer development. J Invest Dermatol 127(5):1244-9. [PubMed: 17159911]  [MGI Ref ID J:121091]

Kato M; Takeda K; Kawamoto Y; Tsuzuki T; Kato Y; Ohno T; Hossain K; Iftakhar-E-Khuda I; Ohgami N; Isobe K; Takahashi M; Nakashima I. 2006. Novel Hairless RET-Transgenic Mouse Line with Melanocytic Nevi and Anagen Hair Follicles. J Invest Dermatol 126(11):2547-50. [PubMed: 16778787]  [MGI Ref ID J:113399]

Kaya G; Tran C; Sorg O; Hotz R; Grand D; Carraux P; Didierjean L; Stamenkovic I; Saurat JH. 2006. Hyaluronate fragments reverse skin atrophy by a CD44-dependent mechanism. PLoS Med 3(12):e493. [PubMed: 17177600]  [MGI Ref ID J:134166]

Kinley JS; Moan J; Dall'Aqua F; Young AR. 1994. Quantitative assessment of epidermal melanogenesis in C3H/Tif hr/hr mice treated with topical furocoumarins and UVA radiation. J Invest Dermatol 103(1):97-103. [PubMed: 8027588]  [MGI Ref ID J:19313]

Kondo T; Shiomoto Y; Kondo T; and Kubo S. 1997. The "NOA" MOUSE; A NEW HAIR-DEFICIENT MUTANT (A POSSIBLE ANIMAL MODEL OF ALLERGIC DERMATITIS) Mouse Genome 95(3):698-700.  [MGI Ref ID J:43274]

Libby RT; Lillo C; Kitamoto J; Williams DS; Steel KP. 2004. Myosin Va is required for normal photoreceptor synaptic activity. J Cell Sci 117(Pt 19):4509-15. [PubMed: 15316067]  [MGI Ref ID J:92181]

MONTAGNA W; CHASE HB; MELARAGNO HP. 1952. The skin of hairless mice. I. The formation of cysts and the distribution of lipids. J Invest Dermatol 19(1):83-94. [PubMed: 14946445]  [MGI Ref ID J:14889]

Mann SJ. 1971. Hair loss and cyst formation in hairless and rhino mutant mice. Anat Rec 170(4):485-99. [PubMed: 5118596]  [MGI Ref ID J:5239]

Markert CL; Silvers WK. 1956. The Effects of Genotype and Cell Environment on Melanoblast Differentiation in the House Mouse. Genetics 41(3):429-50. [PubMed: 17247639]  [MGI Ref ID J:12970]

Meier H; Myers DD; Huebner RJ. 1969. Genetic control by the hr-locus of susceptibility and resistance to leukemia. Proc Natl Acad Sci U S A 63(3):759-66. [PubMed: 4310515]  [MGI Ref ID J:24786]

Mercer JA; Seperack PK; Strobel MC; Copeland NG; Jenkins NA. 1991. Novel myosin heavy chain encoded by murine dilute coat colour locus [published erratum appears in Nature 1991 Aug 8;352(6335):547] Nature 349(6311):709-13. [PubMed: 1996138]  [MGI Ref ID J:11005]

Michna L; Wagner GC; Lou YR; Xie JG; Peng QY; Lin Y; Carlson K; Shih WJ; Conney AH; Lu YP. 2006. Inhibitory effects of voluntary running wheel exercise on UVB-induced skin carcinogenesis in SKH-1 mice. Carcinogenesis 27(10):2108-15. [PubMed: 16699173]  [MGI Ref ID J:113354]

Moore KJ; Swing DA; Copeland NG; Jenkins NA. 1990. Interaction of the murine dilute suppressor gene (dsu) with fourteen coat color mutations [published erratum appears in Genetics 1990 Sep;126(1):285] Genetics 125(2):421-30. [PubMed: 2379821]  [MGI Ref ID J:29467]

Moore KJ; Swing DA; Copeland NG; Jenkins NA. 1994. The murine dilute suppressor gene encodes a cell autonomous suppressor. Genetics 138(2):491-7. [PubMed: 7828830]  [MGI Ref ID J:20796]

Moore KJ; Swing DA; Rinchik EM; Mucenski ML; Buchberg AM; Copeland NG; Jenkins NA. 1988. The murine dilute suppressor gene dsu suppresses the coat-color phenotype of three pigment mutations that alter melanocyte morphology, d, ash and ln. Genetics 119(4):933-41. [PubMed: 3410303]  [MGI Ref ID J:9309]

Morrissey PJ; Parkinson DR; Schwartz RS; Waksal SD. 1980. Immunologic abnormalities in HRS/J mice. I. Specific deficit in T lymphocyte helper function in a mutant mouse. J Immunol 125(4):1558-62. [PubMed: 6447727]  [MGI Ref ID J:6375]

Mucenski ML; Bedigian HG; Shull MM; Copeland NG; Jenkins NA. 1988. Comparative molecular genetic analysis of lymphomas from six inbred mouse strains. J Virol 62(3):839-46. [PubMed: 2828679]  [MGI Ref ID J:25442]

Murphy ED. 1966. Characteristic Tumors. In: Biology of the Laboratory Mouse. McGraw-Hill, New York.  [MGI Ref ID J:24830]

Murray WS. 1934. The breeding behavior of the dilute brown stock of mice (Little dba) Am J Cancer 20:573-593.  [MGI Ref ID J:2464]

O'Sullivan TN; Wu XS; Rachel RA; Huang JD; Swing DA; Matesic LE; Hammer JA rd; Copeland NG; Jenkins NA. 2004. dsu functions in a MYO5A-independent pathway to suppress the coat color of dilute mice. Proc Natl Acad Sci U S A 101(48):16831-6. [PubMed: 15550542]  [MGI Ref ID J:94728]

PIERRO LJ; CHASE HB. 1963. Slate--a new coat color mutant in the mouse. J Hered 54:47-50. [PubMed: 13943454]  [MGI Ref ID J:25388]

Panteleyev AA; Botchkareva NV; Sundberg JP; Christiano AM; Paus R. 1999. The role of the hairless (hr) gene in the regulation of hair follicle catagen transformation. Am J Pathol 155(1):159-71. [PubMed: 10393848]  [MGI Ref ID J:56076]

Panteleyev AA; van der Veen C; Rosenbach T; Muller-Rover S; Sokolov VE ; Paus R. 1998. Towards defining the pathogenesis of the hairless phenotype. J Invest Dermatol 110(6):902-7. [PubMed: 9620297]  [MGI Ref ID J:47743]

Pastural E; Barrat FJ; Dufourcq-Lagelouse R; Certain S; Sanal O ; Jabado N ; Seger R ; Griscelli C ; Fischer A ; de Saint Basile G. 1997. Griscelli disease maps to chromosome 15q21 and is associated with mutations in the myosin-Va gene. Nat Genet 16(3):289-92. [PubMed: 9207796]  [MGI Ref ID J:41253]

Pauling L. 1991. Effect of ascorbic acid on incidence of spontaneous mammary tumors and UV-light-induced skin tumors in mice. Am J Clin Nutr 54(6 Suppl):1252S-1255S. [PubMed: 1962578]  [MGI Ref ID J:634]

Pirinen E; Kuulasmaa T; Pietila M; Heikkinen S; Tusa M; Itkonen P; Boman S; Skommer J; Virkamaki A; Hohtola E; Kettunen M; Fatrai S; Kansanen E; Koota S; Niiranen K; Parkkinen J; Levonen AL; Yla-Herttuala S; Hiltunen JK; Alhonen L; Smith U; Janne J; Laakso M. 2007. Enhanced polyamine catabolism alters homeostatic control of white adipose tissue mass, energy expenditure, and glucose metabolism. Mol Cell Biol 27(13):4953-67. [PubMed: 17485446]  [MGI Ref ID J:122759]

Pottathil R; Meier H; Huebner RJ. 1978. Suppression of leukemogenesis in hairless mice by anti-type C viral immune gamma globulins. Naturwissenschaften 65(8):443-4. [PubMed: 213736]  [MGI Ref ID J:6059]

Provance DW Jr; Wei M; Ipe V; Mercer JA. 1996. Cultured melanocytes from dilute mutant mice exhibit dendritic morphology and altered melanosome distribution. Proc Natl Acad Sci U S A 93(25):14554-8. [PubMed: 8962090]  [MGI Ref ID J:37976]

RIKEN BioResource Center/RIKEN Genomic Sciences Center. 2008. A Large Scale Mutagenesis Program in RIKEN GSC PhenoSITE, World Wide Web (URL: http://www.brc.riken.jp/lab/gsc/mouse/) :.  [MGI Ref ID J:133634]

Reske-Kunz AB; Scheid MP; Boyse EA. 1979. Disproportion in T-cell subpopulations in immunodeficient mutant hr/hr mice. J Exp Med 149(1):228-33. [PubMed: 310859]  [MGI Ref ID J:6087]

Russell ES. 1949. A Quantitative Histological Study of the Pigment Found in the Coat-Color Mutants of the House Mouse. IV. the Nature of the Effects of Genic Substitution in Five Major Allelic Series. Genetics 34(2):146-66. [PubMed: 17247308]  [MGI Ref ID J:12958]

Sato J; Yanai M; Hirao T; Denda M. 2000. Water content and thickness of the stratum corneum contribute to skin surface morphology. Arch Dermatol Res 292(8):412-7. [PubMed: 10994776]  [MGI Ref ID J:116955]

Staats J. 1985. Standardized Nomenclature for Inbred Strains of Mice: eighth listing. Cancer Res 45(3):945-77. [PubMed: 3971387]  [MGI Ref ID J:50296]

Starcher B; O'Neal P; Granstein RD; Beissert S. 1996. Inhibition of neutrophil elastase suppresses the development of skin tumors in hairless mice. J Invest Dermatol 107(2):159-63. [PubMed: 8757756]  [MGI Ref ID J:34446]

Stoye JP; Fenner S; Greenoak GE; Moran C; Coffin JM. 1988. Role of endogenous retroviruses as mutagens: the hairless mutation of mice. Cell 54(3):383-91. [PubMed: 2840205]  [MGI Ref ID J:9252]

Sundberg JP (ed.). 1994. . In: Handbook of Mouse Mutations with Skin and Hair Abnormalities: Animal Models and Biomedical Tools. CRC Press, Boca Raton.  [MGI Ref ID J:30359]

Sundberg JP; Sundberg BA; Beamer WG. 1997. Comparison of chemical carcinogen skin tumor induction efficacy in inbred, mutant, and hybrid strains of mice: Morphologic variations of induced tumors and absence of a papillomavirus cocarcinogen. Mol Carcinog 20(1):19-32. [PubMed: 9328433]  [MGI Ref ID J:43880]

Sweet HO. 1983. Dilute suppressor, a new suppressor gene in the house mouse. J Hered 74(4):305-6. [PubMed: 6886377]  [MGI Ref ID J:7171]

Tober KL; Thomas-Ahner JM; Kusewitt DF; Oberyszyn TM. 2007. Effects of UVB on E prostanoid receptor expression in murine skin. J Invest Dermatol 127(1):214-21. [PubMed: 16917495]  [MGI Ref ID J:116974]

Tsukahara K; Kakuo S; Moriwaki S; Hotta M; Ohuchi A; Kitahara T; Harada N. 2008. The characteristics of aromatase deficient hairless mice indicate important roles of extragonadal estrogen in the skin. J Steroid Biochem Mol Biol 108(1-2):82-90. [PubMed: 17951050]  [MGI Ref ID J:130515]

Vollmar B; Morgenthaler M; Amon M; Menger MD. 2000. Skin microvascular adaptations during maturation and aging of hairless mice Am J Physiol Heart Circ Physiol 279(4):H1591-9. [PubMed: 11009445]  [MGI Ref ID J:65226]

Wang XP; Schunck M; Kallen KJ; Neumann C; Trautwein C; Rose-John S; Proksch E. 2004. The interleukin-6 cytokine system regulates epidermal permeability barrier homeostasis. J Invest Dermatol 123(1):124-31. [PubMed: 15191552]  [MGI Ref ID J:90509]

Wilgus TA; Koki AT; Zweifel BS; Rubal PA; Oberyszyn TM. 2003. Chemotherapeutic efficacy of topical celecoxib in a murine model of ultraviolet light B-induced skin cancer. Mol Carcinog 38(1):33-9. [PubMed: 12949841]  [MGI Ref ID J:85679]

Yoshimura A; Fujii R; Watanabe Y; Okabe S; Fukui K; Takumi T. 2006. Myosin-Va facilitates the accumulation of mRNA/protein complex in dendritic spines. Curr Biol 16(23):2345-51. [PubMed: 17141617]  [MGI Ref ID J:117928]

Zarach JM; Beaudoin GM rd; Coulombe PA; Thompson CC. 2004. The co-repressor hairless has a role in epithelial cell differentiation in the skin. Development 131(17):4189-200. [PubMed: 15280217]  [MGI Ref ID J:92053]

Zhang W; Hanks AN; Boucher K; Florell SR; Allen SM; Alexander A; Brash DE; Grossman D. 2005. UVB-induced apoptosis drives clonal expansion during skin tumor development. Carcinogenesis 26(1):249-57. [PubMed: 15498793]  [MGI Ref ID J:95011]

van Schanke A; Jongsma MJ; Bisschop R; van Venrooij GM; Rebel H; de Gruijl FR. 2005. Single UVB Overexposure Stimulates Melanocyte Proliferation in Murine Skin, in Contrast to Fractionated or UVA-1 Exposure. J Invest Dermatol 124(1):241-7. [PubMed: 15654980]  [MGI Ref ID J:96282]