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Strain Name:

AKXD23/TyJ

Stock Number:

000780

Availability:

Repository-Cryopreserved

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General Terms and Conditions

Former Name      AKXD-23/TyJ    (Changed: 15-DEC-04 )
Genes & Alleles   Emv11;   Emv14;   Rmcf;   Rmcfs;   ;

Product Information

Strain Details

Type Recombinant Inbred (Ri)
Additional information on Recombinant Inbred Mice.
Specieslaboratory mouse
RI progenitor AKR/J DBA/2J
H2 Haplotyped

Appearance
albino
Related Genotype: Tyrc/Tyrc

Mammalian Phenotype Terms assigned by genotype

  • tumorigenesis
  • lymphoma (MGI Ref ID J:20300)
    • propensity to develop lymphoma with mean age of onset 445 days

    • Gene & Allele Details

    Allele Symbol Rmcfs
    Allele Name MCF sensitive
    Gene Symbol and Name Rmcf, resistance to MCF virus
    Chromosome 5
    Gene Symbol and Name Emv11, endogenous ecotropic MuLV 11
    Chromosome 7
    Gene Common Name(s) AKR leukemia virus inducer 1; Akv-1; Emv-11;
    Gene Symbol and Name Emv14, endogenous ecotropic MuLV 14
    Chromosome 11
    Gene Common Name(s) AKR leukemia virus inducer 4; Akv-2J; Akv-4; Emv-14;

    Related Strains

    AKXD Strains
    001005   AKXD1/TyJ
    001017   AKXD10/TyJ
    001003   AKXD11/TyJ
    000765   AKXD13/TyJ
    000779   AKXD14/TyJ
    000954   AKXD15/TyJ
    000958   AKXD16/TyJ
    001093   AKXD18/TyJ
    000776   AKXD2/TyJ
    001001   AKXD20/TyJ
    001062   AKXD21/TyJ
    000947   AKXD22/TyJ
    000969   AKXD24/TyJ
    000949   AKXD25/TyJ
    000764   AKXD27/TyJ
    000957   AKXD28/TyJ
    000959   AKXD3/TyJ
    000777   AKXD6/TyJ
    000763   AKXD9/TyJ
    View AKXD Strains     (19 strains)

    Strains carrying   Rmcfs allele
    000646   A/J
    000648   AKR/J
    000779   AKXD14/TyJ
    000764   AKXD27/TyJ
    000777   AKXD6/TyJ
    000667   C57BR/cdJ
    000668   C57L/J
    000669   C58/J
    000682   RF/J
    000644   SEA/GnJ
    000686   SJL/J
    000688   ST/bJ
    View Strains carrying   Rmcfs     (12 strains)

    Phenotypic Data

    Mouse Phenome Database
    Wellcome Trust Centre for Human Genetics: Mouse Recombinant Inbred Line (RIL) Genotype Data for AKXD RI Line

    Research Applications

    This mouse can be used to support research in many areas including:

    Research Tools
    Cancer Research (genes regulating lymphoma development)
    Genetics Research (Gene Mapping: Tools for QTL Mapping, Segregation and Linkage Analysis)

    References

    Selected Reference(s)

    Mucenski ML; Taylor BA; Jenkins NA; Copeland NG. 1986. AKXD recombinant inbred strains: models for studying the molecular genetic basis of murine lymphomas. Mol Cell Biol 6(12):4236-43. [PubMed: 3025647]  [MGI Ref ID J:20300]

    Additional References

    Price and Supply Information

    Strain Name: AKXD23/TyJ
    Stock Number: 000780

    Price Details

    IMPORTANT NOTE: Prices are based on shipping destination. To view prices, select your shipping destination.

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    Supply Details

    Standard SupplyRepository-Cryopreserved. Must Be Recovered. Please refer to pricing and supply notes for further information.
    Supply Notes Cryorecovery - Standard.
    The recovery process begins when a signed agreement form is returned to the Customer Service Department after order placement. Although results vary by strain, at least two males and two females (two pairs) will be provided, typically within 15 weeks of our receipt of the signed agreement form. If the first recovery attempt is unsuccessful or only one pair is recovered, a second recovery will be done, extending the delivery time to approximately 25 weeks. At least one member of each pair will be of known genotype and will carry the mutation if it is a mutant strain. Please note that pairs may not reflect the mating scheme utilized by The Jackson Laboratory prior to cryopreservation of the strain. Mating schemes are sometimes modified for successful cryopreservation. Price represents a repository maintenance fee, which includes the cost of recovery of the strain from the cryopreservation resource and the periodic replacement of the frozen embryos used for recovery.

    Cryorecovery to establish a Dedicated Supply for greater quantities of mice.
    One to two pairs will be recovered to establish a Dedicated Supply of mice. Price by quotation. For more information on Dedicated Supply, please contact JAX® Services: Tel: 1-800-422-6423 or 1-207-288-5845; Email: jaxservices@jax.org.
    Genomic DNA is available for this strain from the Mouse DNA Resource.

    LicensingSee General Terms and Conditions below  

    General Terms and Conditions

    View JAX® Mice & Services Conditions of Use.

    The Jackson Laboratory's Genotype Promise

    The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.
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