Strain Name:

RBJ/DnJ

Stock Number:

000807

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Description

The genotypes of the animals provided may not reflect those discussed in the strain description or the mating scheme utilized by The Jackson Laboratory prior to cryopreservation. Please inquire for possible genotypes for this specific strain.

Strain Information

Type Chromosome Aberration; Robertsonian; Translocation;
Additional information on Mice with Chromosomal Aberrations.
Type Inbred Strain;
Additional information on Inbred Strains.
Visit our online Nomenclature tutorial.
Specieslaboratory mouse and M. m. domesticus
GenerationF32
Generation Definitions

Appearance
dark agouti, retinal degeneration
Related Genotype: A/A Mc1rE-tob/Mc1rE-tob rd3/rd3

Important Note
This strain is homozygous for retinal degeneration 3, rd3.

Control Information

  Control
   None Available
 
  Considerations for Choosing Controls

Related Strains

Combined Robertsonian Chromosome Stocks
002040   RB126Bnr/EiJ
002041   RB16Bnr/EiJ
001000   RBD/DnJ
000726   RBF/DnJ
000896   STOCK Rb(2.18)6Rma Rb(12.14)8Rma/J
000864   STOCK Rb(2.8)2Lub Rb(7.18)9Lub/J
000929   TIRANO/EiJ
001746   WMP/PasDnJ
001392   ZALENDE/EiJ
View Combined Robertsonian Chromosome Stocks     (9 strains)

Strains carrying   Mc1rE-tob allele
001000   RBD/DnJ
000726   RBF/DnJ
000729   STOCK Rb(11.13)4Bnr/J
View Strains carrying   Mc1rE-tob     (3 strains)

Strains carrying   Rd3rd3 allele
008627   B6.Cg-Rd3rd3/Boc
000726   RBF/DnJ
000852   STOCK In(5)30Rk/J
000729   STOCK Rb(11.13)4Bnr/J
View Strains carrying   Rd3rd3     (4 strains)

Strains carrying other alleles of Hprt
004302   129S1/Sv-Hprttm1(cre)Mnn/J
002027   129S8/SvEv-Gpi1c Hprtb-m2/J
008710   B6.129P2(129S4)-Hprttm10(Ple162-EGFP/cre)Ems/Mmjax
008877   B6.129P2(129S4)-Hprttm12(Ple177-EGFP/cre)Ems/Mmjax
009114   B6.129P2(129S4)-Hprttm14(Ple103-EGFP/cre)Ems/Mmjax
009116   B6.129P2(129S4)-Hprttm16(Ple167-EGFP/cre)Ems/Mmjax
008709   B6.129P2(129S4)-Hprttm9(Ple178-EGFP/cre)Ems/Mmjax
009113   B6.129P2(Cg)-Hprttm13(Ple54-EGFP)Ems/Mmjax
009115   B6.129P2(Cg)-Hprttm15(Ple111-EGFP)Ems/Mmjax
009348   B6.129P2(Cg)-Hprttm17(Ple48-lacZ)Ems/Mmjax
009118   B6.129P2(Cg)-Hprttm18(Ple90-EGFP)Ems/Mmjax
012572   B6.129P2(Cg)-Hprttm19(Ple88-lacZ)Ems/Mmjax
009353   B6.129P2(Cg)-Hprttm20(Ple53-EGFP)Ems/Mmjax
009596   B6.129P2(Cg)-Hprttm33(Ple183-EGFP)Ems/Mmjax
010770   B6.129P2(Cg)-Hprttm34(Ple186-EGFP)Ems/Mmjax
012574   B6.129P2(Cg)-Hprttm38(Ple17-lacZ)Ems/Mmjax
012575   B6.129P2(Cg)-Hprttm39(Ple24-lacZ)Ems/Mmjax
008706   B6.129P2(Cg)-Hprttm4(Ple88-EGFP)Ems/Mmjax
012576   B6.129P2(Cg)-Hprttm40(Ple34-lacZ)Ems/Mmjax
010805   B6.129P2(Cg)-Hprttm41(Ple160-lacZ)Ems/Mmjax
012331   B6.129P2(Cg)-Hprttm42(Ple131-lacZ)Ems/Mmjax
012577   B6.129P2(Cg)-Hprttm43(Ple140-lacZ)Ems/Mmjax
010709   B6.129P2(Cg)-Hprttm44(Ple49-lacZ)Ems/Mmjax
012333   B6.129P2(Cg)-Hprttm45(Ple67-lacZ)Ems/Mmjax
012733   B6.129P2(Cg)-Hprttm53(CAG-lacZ)Ems/Mmjax
010789   B6.129P2(Cg)-Hprttm54(Ple233-EGFP)Ems/Mmjax
012578   B6.129P2(Cg)-Hprttm56(Ple25-lacZ)Ems/Mmjax
012579   B6.129P2(Cg)-Hprttm58(Ple119-lacZ)Ems/Mmjax
012580   B6.129P2(Cg)-Hprttm59(Ple123-lacZ)Ems/Mmjax
012581   B6.129P2(Cg)-Hprttm62(Ple153-lacZ)Ems/Mmjax
012342   B6.129P2(Cg)-Hprttm63(Ple12-lacZ)Ems/Mmjax
012347   B6.129P2(Cg)-Hprttm64(Ple170-lacZ)Ems/Mmjax
012582   B6.129P2(Cg)-Hprttm67(Ple238-lacZ)Ems/Mmjax
012583   B6.129P2(Cg)-Hprttm68(Ple127-lacZ)Ems/Mmjax
008707   B6.129P2(Cg)-Hprttm7(Ple185-EGFP)Ems/Mmjax
012656   B6.129P2(Cg)-Hprttm70(Ple240-lacZ)Ems/Mmjax
012657   B6.129P2(Cg)-Hprttm71(Ple155-lacZ)Ems/Mmjax
012659   B6.129P2(Cg)-Hprttm73(Ple142-lacZ)Ems/Mmjax
012734   B6.129P2(Cg)-Hprttm74(Ple232-lacZ)Ems/Mmjax
008708   B6.129P2(Cg)-Hprttm8(Ple151-EGFP)Ems/Mmjax
002171   B6.129P2-Hprtb-m3/J
023676   B6.Cg-Hprttm331(Ple275-icre/ERT2)Ems/Mmjax
023678   B6.Cg-Hprttm333(Ple281-icre/ERT2)Ems/Mmjax
023679   B6.Cg-Hprttm334(Ple279-icre/ERT2)Ems/Mmjax
023680   B6.Cg-Hprttm335(Ple277-icre/ERT2)Ems/Mmjax
023685   B6.Cg-Hprttm340(Ple252-icre/ERT2)Ems/Mmjax
023686   B6.Cg-Hprttm341(Ple273-icre/ERT2)Ems/Mmjax
023688   B6.Cg-Hprttm343(Ple270-icre/ERT2)Ems/Mmjax
023709   B6.Cg-Hprttm364(CAG-icre/ERT2)Ems/Mmjax
023710   B6.Cg-Hprttm365(Ple266-icre/ERT2)Ems/Mmjax
014536   B6.Cg-Hprttm75(Ple143-lacZ)Ems/Mmjax
021427   B6;129-Hprttm1(CMV-GFP)Nat/J
003138   B6;129-Hprttm1Detl/J
021428   B6;129-Hprttm2(CMV-tdTomato)Nat/J
012480   NOD.Cg-Prkdcscid Il2rgtm1Wjl Hprtb-m3/EshJ
024746   STOCK Gt(ROSA)26Sortm1.1(rtTA,EGFP)Nagy Hprttm1(tetO-Dkk1)Spdl Tg(TCF/Lef1-lacZ)34Efu/J
008876   STOCK Hprttm11(Ple176-EGFP/cre)Ems/Mmjax
009349   STOCK Hprttm31(Ple67-EGFP)Ems/Mmjax
009594   STOCK Hprttm32(Ple112-EGFP)Ems/Mmjax
010707   STOCK Hprttm37(lacZ)Ems/Mmjax
012335   STOCK Hprttm50(Ple55-lacZ)Ems/Mmjax
013764   STOCK Hprttm57(Ple26-lacZ)Ems/Mmjax
012353   STOCK Hprttm65(Ple53-lacZ)Ems/Mmjax
012354   STOCK Hprttm66(Ple5-lacZ)Ems/Mmjax
012584   STOCK Hprttm69(Ple134-lacZ)Ems/Mmjax
View Strains carrying other alleles of Hprt     (65 strains)

Strains carrying other alleles of Mc1r
003625   B6.C-H2-Ab1bm12/KhEg-Mc1re-J/J
001434   C3HeB/FeJ x STX/Le-Mc1rE-so Gli3Xt-J Zeb1Tw/J
001533   C3HeB/FeJ-Mc1rE-so Gli3Xt-J/J
000060   C57BL/6J-Mc1re/J
View Strains carrying other alleles of Mc1r     (4 strains)

Strains carrying other alleles of Rb(16.17)7Bnr
014119   B6.Cg-Rb(16.17)7Bnr/JAmonJ
001000   RBD/DnJ
003304   STOCK Rb(16.17)7Bnr-Myo15sh2-2J/J
000929   TIRANO/EiJ
001392   ZALENDE/EiJ
View Strains carrying other alleles of Rb(16.17)7Bnr     (5 strains)

Strains carrying other alleles of Rb(2.8)2Lub
000929   TIRANO/EiJ
View Strains carrying other alleles of Rb(2.8)2Lub     (1 strain)

Strains carrying other alleles of Rb(5.15)3Bnr
001000   RBD/DnJ
View Strains carrying other alleles of Rb(5.15)3Bnr     (1 strain)

Phenotype

Phenotype Information

View Related Disease (OMIM) Terms

Related Disease (OMIM) Terms provided by MGI
- Potential model based on gene homology relationships. Phenotypic similarity to the human disease has not been tested.
Albinism, Oculocutaneous, Type II; OCA2   (MC1R)
Kelley-Seegmiller Syndrome   (HPRT1)
Leber Congenital Amaurosis 12; LCA12   (RD3)
Lesch-Nyhan Syndrome; LNS   (HPRT1)
Melanoma, Cutaneous Malignant, Susceptibility to, 5; CMM5   (MC1R)
View Research Applications

Research Applications
This mouse can be used to support research in many areas including:

Sensorineural Research
Retinal Degeneration
      rd3

Mc1rE-tob related

Endocrine Deficiency Research
Skin Defects

Rd3rd3 related

Sensorineural Research
Retinal Degeneration
      Homozygous for rd3

Genes & Alleles

Gene & Allele Information provided by MGI

 
Allele Symbol Hprttm7Detl
Allele Name targeted mutation 7, Peter J Detloff
Allele Type Targeted
Common Name(s) hprtNosignalQ38;
Strain of Origin(129X1/SvJ x 129S1/Sv)F1-Kitl<+>
ES Cell Line NameR1
ES Cell Line Strain(129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Promoter Hprt, hypoxanthine guanine phosphoribosyl transferase, mouse, laboratory
Molecular Note Exon 3 was disrupted by the insertion of a cassette containing a myc tag, and 38 CAG repeats encoding 38 glutamine residues. Neither a nuclear localization signal (NLS) nor a nuclear export signal (NES) was included in the targeting construct. [MGI Ref ID J:84451]
 
Allele Symbol Mc1rE-tob
Allele Name tobacco darkening
Allele Type Spontaneous
Common Name(s) Etob;
Strain of OriginM. m. domesticus poschiavinus
Gene Symbol and Name Mc1r, melanocortin 1 receptor
Chromosome 8
Gene Common Name(s) CMM5; MSH-R; Mshra; SHEP2; Tob; e; extension recessive yellow; extension, recessive yellow; melanocyte hormone receptor alpha; tobacco darkening;
General Note Mc1rE-tob, tobacco darkening, semidominant. Formerly Etob. Mice of the species Mus poschiavinus, the tobacco mouse, are homozygous for this allele. They are black in color until the eighth week, after which the flanks become agouti.In descendants from crosses with Mus musculus, Mc1rE-tob/+ heterozygotes show an agouti pattern with darkened back. Mc1rE-tob/Mc1re a/a mice are black (J:22593, J:13641). The Mc1rE-tob allele carries two point mutations that result in a receptor that is overactive, though responsive to hormone regulation, and produces a greater activation of the MC1R effector, G protein-coupled adenylyl cyclase, than does the wild-type allele (J:4636).
Molecular Note Two independent PCR assays found a C-to-T mutation at position 206 predicted to result in a serine to leucine alteration in codon 69. A second nucleotide C-to-T change results in a silent mutation at position 166. [MGI Ref ID J:4636]
 
Allele Symbol Rd3rd3
Allele Name retinal degeneration 3
Allele Type Spontaneous
Strain of OriginRBF/DnJ
Gene Symbol and Name Rd3, retinal degeneration 3
Chromosome 1
Gene Common Name(s) 3322402L07Rik; C1orf36; LCA12; RIKEN cDNA 3322402L07 gene; rd-3;
General Note This mutation causes retinal degeneration. In homozygous mutant mice, development proceeds normally through the second postnatal week. Thereafter, photoreceptor and outer nuclear layers begin to degenerate, and by 8 weeks, no photoreceptor cells remain. Changes in electroretinograms parallel the histologic changes. As of 1998 this is the only type of retinal degeneration reported in mice in which the photoreceptors are initially normal (J:4367).
Molecular Note A C to T substitution in Rd3 results in a stop codon after residue 106. The truncated protein is initially expressed in in vitro assays but is degraded. [MGI Ref ID J:122439]
 
Gene Symbol and Name Rb(5.15)3Bnr, Robertsonian translocation, Chr 5 and 15, Universitat Bonn/Rhein 3
Chromosome 15
Gene Common Name(s) Rb3Bnr;
 
Gene Symbol and Name Rb(2.8)2Lub, Robertsonian translocation, Chr 2 and 8, Lubeck 2
Chromosome 2
Gene Common Name(s) Rb2Lub;
 
Gene Symbol and Name Rb(16.17)7Bnr, Robertsonian translocation, Chr 16 and 17, Universitat Bonn/Rhein 7
Chromosome 16
Gene Common Name(s) Rb7Bnr;

Genotyping

Genotyping Information


Helpful Links

Genotyping resources and troubleshooting

References

References provided by MGI

Additional References

Chang B; Heckenlively JR; Hawes NL; Roderick TH. 1993. New mouse primary retinal degeneration (rd-3). Genomics 16(1):45-9. [PubMed: 8486383]  [MGI Ref ID J:4367]

Hprttm7Detl related

Jackson WS; Tallaksen-Greene SJ; Albin RL; Detloff PJ. 2003. Nucleocytoplasmic transport signals affect the age at onset of abnormalities in knock-in mice expressing polyglutamine within an ectopic protein context. Hum Mol Genet 12(13):1621-9. [PubMed: 12812988]  [MGI Ref ID J:84451]

Mc1rE-tob related

Gropp A; Tettenborn U; Lehmann E von. 1969. [Chromosome studies in the tobacco mouse (M. poschiavinus) and in tobacco mouse hybrids] Experientia 25(8):875-6. [PubMed: 5348563]  [MGI Ref ID J:24452]

Gropp A; Tettenborn U; Lehmann E von. 1970. [Chromosome variations on the Robertson type in the tobacco mouse, M. Poschiavinus, and its hybrids with the laboratory mouse] Cytogenetics 9(1):9-23. [PubMed: 5412048]  [MGI Ref ID J:23097]

Robbins LS; Nadeau JH; Johnson KR; Kelly MA; Roselli-Rehfuss L; Baack E; Mountjoy KG; Cone RD. 1993. Pigmentation phenotypes of variant extension locus alleles result from point mutations that alter MSH receptor function. Cell 72(6):827-34. [PubMed: 8458079]  [MGI Ref ID J:4636]

Silvers WK. 1979. The Coat Colors of Mice; A Model for Mammalian Gene Action and Interaction. In: The Coat Colors of Mice. Springer-Verlag, New York.  [MGI Ref ID J:78801]

von Lehmann E. 1973. Coat colour genetics of the tobacco-mouse (Mus poschiavinus Fatio) Mouse News Lett 48:23.  [MGI Ref ID J:22593]

von Lehmann E. 1974. Weitere Mitteilungen zu: coat colour genetics of the tobacco-mouse (Mus poschiavinus Fatio). Mouse News Lett 50:26-7.  [MGI Ref ID J:13641]

Rd3rd3 related

Azadi S; Molday LL; Molday RS. 2010. RD3, the protein associated with Leber congenital amaurosis type 12, is required for guanylate cyclase trafficking in photoreceptor cells. Proc Natl Acad Sci U S A 107(49):21158-63. [PubMed: 21078983]  [MGI Ref ID J:167162]

Chang B; Hawes NL; Hurd RE; Davisson MT; Nusinowitz S; Heckenlively JR. 2002. Retinal degeneration mutants in the mouse. Vision Res 42(4):517-25. [PubMed: 11853768]  [MGI Ref ID J:75095]

Chang B; Hawes NL; Hurd RE; Wang J; Howell D; Davisson MT; Roderick TH; Nusinowitz S; Heckenlively JR. 2005. Mouse models of ocular diseases. Vis Neurosci 22(5):587-93. [PubMed: 16332269]  [MGI Ref ID J:156373]

Chang B; Heckenlively JR; Hawes NL; Roderick TH. 1993. New mouse primary retinal degeneration (rd-3). Genomics 16(1):45-9. [PubMed: 8486383]  [MGI Ref ID J:4367]

Cheng CL; Molday RS. 2013. Changes in gene expression associated with retinal degeneration in the rd3 mouse. Mol Vis 19:955-69. [PubMed: 23687432]  [MGI Ref ID J:202634]

Danciger M; Ogando D; Yang H; Matthes MT; Yu N; Ahern K; Yasumura D; Williams RW; Lavail MM. 2008. Genetic modifiers of retinal degeneration in the rd3 mouse. Invest Ophthalmol Vis Sci 49(7):2863-9. [PubMed: 18344445]  [MGI Ref ID J:136923]

Friedman JS; Chang B; Kannabiran C; Chakarova C; Singh HP; Jalali S; Hawes NL; Branham K; Othman M; Filippova E; Thompson DA; Webster AR; Andreasson S; Jacobson SG; Bhattacharya SS; Heckenlively JR; Swaroop A. 2006. Premature truncation of a novel protein, RD3, exhibiting subnuclear localization is associated with retinal degeneration. Am J Hum Genet 79(6):1059-70. [PubMed: 17186464]  [MGI Ref ID J:122439]

Hawes NL; Smith RS; Chang B; Davisson M; Heckenlively JR; John SW. 1999. Mouse fundus photography and angiography: a catalogue of normal and mutant phenotypes. Mol Vis 5:22. [PubMed: 10493779]  [MGI Ref ID J:59481]

Heckenlively JR; Chang B; Erway LC; Peng C; Hawes NL; Hageman GS; Roderick TH. 1995. Mouse model for Usher syndrome: linkage mapping suggests homology to Usher type I reported at human chromosome 11p15. Proc Natl Acad Sci U S A 92(24):11100-4. [PubMed: 7479945]  [MGI Ref ID J:121993]

Pieke-Dahl S; Ohlemiller KK; McGee J; Walsh EJ; Kimberling WJ. 1997. Hearing loss in the RBF/DnJ mouse, a proposed animal model of Usher syndrome type IIa. Hear Res 112(1-2):1-12. [PubMed: 9367224]  [MGI Ref ID J:44148]

Won J; Shi LY; Hicks W; Wang J; Hurd R; Naggert JK; Chang B; Nishina PM. 2011. Mouse model resources for vision research. J Ophthalmol 2011:391384. [PubMed: 21052544]  [MGI Ref ID J:166679]

Health & husbandry

Health & Colony Maintenance Information

Animal Health Reports

Production of mice from cryopreserved embryos or sperm occurs in a maximum barrier room, G200.

Pricing and Purchasing

Pricing, Supply Level & Notes, Controls


Pricing for USA, Canada and Mexico shipping destinations View International Pricing

Cryopreserved

Cryopreserved Mice - Ready for Recovery

Price (US dollars $)
Cryorecovery* $3300.00
Animals Provided

At least two mice that carry the mutation (if it is a mutant strain) will be provided. Their genotypes may not reflect those discussed in the strain description. Please inquire for possible genotypes and see additional details below.

Standard Supply

Cryopreserved. Ready for recovery. Please refer to pricing and supply notes on the strain data sheet for further information.

Supply Notes

  • Cryorecovery - Standard.
    Progeny testing is not required.

    The average number of mice provided from recovery of our cryopreserved strains is 10. The total number of animals provided, their gender and genotype will vary. We will fulfill your order by providing at least two pair of mice, at least one animal of each pair carrying the mutation of interest. Please inquire if larger numbers of animals with specific genotype and genders are needed. Animals typically ship between 10 and 14 weeks from the date of your order. If a second cryorecovery is needed in order to provide the minimum number of animals, animals will ship within 25 weeks. IMPORTANT NOTE: The genotypes of animals provided may not reflect the mating scheme utilized by The Jackson Laboratory prior to cryopreservation, or that discussed in the strain description. Please inquire about possible genotypes which will be recovered for this specific strain. The Jackson Laboratory cannot guarantee the reproductive success of mice shipped to your facility. If the mice are lost after the first three days (post-arrival) or do not produce progeny at your facility, a new order and fee will be necessary.

    Cryorecovery to establish a Dedicated Supply for greater quantities of mice. Mice recovered can be used to establish a dedicated colony to contractually supply you mice according to your requirements. Price by quotation. For more information on Dedicated Supply, please contact JAX® Services, Tel: 1-800-422-6423 (from U.S.A., Canada or Puerto Rico only) or 1-207-288-5845 (from any location).

Pricing for International shipping destinations View USA Canada and Mexico Pricing

Cryopreserved

Cryopreserved Mice - Ready for Recovery

Price (US dollars $)
Cryorecovery* $4290.00
Animals Provided

At least two mice that carry the mutation (if it is a mutant strain) will be provided. Their genotypes may not reflect those discussed in the strain description. Please inquire for possible genotypes and see additional details below.

Standard Supply

Cryopreserved. Ready for recovery. Please refer to pricing and supply notes on the strain data sheet for further information.

Supply Notes

  • Cryorecovery - Standard.
    Progeny testing is not required.

    The average number of mice provided from recovery of our cryopreserved strains is 10. The total number of animals provided, their gender and genotype will vary. We will fulfill your order by providing at least two pair of mice, at least one animal of each pair carrying the mutation of interest. Please inquire if larger numbers of animals with specific genotype and genders are needed. Animals typically ship between 10 and 14 weeks from the date of your order. If a second cryorecovery is needed in order to provide the minimum number of animals, animals will ship within 25 weeks. IMPORTANT NOTE: The genotypes of animals provided may not reflect the mating scheme utilized by The Jackson Laboratory prior to cryopreservation, or that discussed in the strain description. Please inquire about possible genotypes which will be recovered for this specific strain. The Jackson Laboratory cannot guarantee the reproductive success of mice shipped to your facility. If the mice are lost after the first three days (post-arrival) or do not produce progeny at your facility, a new order and fee will be necessary.

    Cryorecovery to establish a Dedicated Supply for greater quantities of mice. Mice recovered can be used to establish a dedicated colony to contractually supply you mice according to your requirements. Price by quotation. For more information on Dedicated Supply, please contact JAX® Services, Tel: 1-800-422-6423 (from U.S.A., Canada or Puerto Rico only) or 1-207-288-5845 (from any location).

View USA Canada and Mexico Pricing View International Pricing

Standard Supply

Cryopreserved. Ready for recovery. Please refer to pricing and supply notes on the strain data sheet for further information.

Control Information

  Control
   None Available
 
  Considerations for Choosing Controls
  Control Pricing Information for Genetically Engineered Mutant Strains.
 

Important Note

This strain is homozygous for retinal degeneration 3, rd3.

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The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.
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MICE and PRODUCTS are to be used in a safe manner and in accordance with all applicable governmental rules and regulations.

The foregoing represents the General Terms and Conditions applicable to JACKSON’s MICE, PRODUCTS or services. In addition, special terms and conditions of sale of certain MICE, PRODUCTS or services may be set forth separately in JACKSON web pages, catalogs, price lists, contracts, and/or other documents, and these special terms and conditions shall also govern the sale of these MICE, PRODUCTS and services by JACKSON, and by its licensees and distributors.

Acceptance of delivery of MICE, PRODUCTS or services shall be deemed agreement to these terms and conditions. No purchase order or other document transmitted by purchaser or recipient that may modify the terms and conditions hereof, shall be in any way binding on JACKSON, and instead the terms and conditions set forth herein, including any special terms and conditions set forth separately, shall govern the sale of MICE, PRODUCTS or services by JACKSON.


(6.8)