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Type Inbred Strain; Additional information on Inbred Strains. Type Wild-Derived; Additional information on Wild-Derived Mice. Visit our online Nomenclature tutorial. Mating System Sibling x Sibling (Female x Male) Species M. spretus (Spain) Generation F81 (12-JAN-09) Geographic Origin Puerto Real, Cadiz Province, Spain Appearance
white-bellied agouti
Related Genotype: Aw/AwDescription
The wild-derived inbred strain SPRET/Ei is often used in crosses with common inbred strains to create highly polymorphic panels for genetic mapping. SPRET/Ei mice are resistant to high doses of tumor necrosis factor alpha (TNFa) (Staelens et al 2002). Mice from a C57BL/6 x SPRET/Ei F1 cross were protected from TNFa-induced arthritis and partially protected against induced allergic asthma (Staelens et al 2004). SPRET/Ei may be useful in understanding certain inflammatory diseases.
Genetic Quality Control Annual Report
JAX® NOTES, Winter 1995; 460. Wild-Derived Mice Strains - Tips on Their Care and Handling.
View Phenotypic Data
Phenotypic Data
Mouse Phenome Database
Mouse Phenome Database / SNP Facility
This strain will not have a genotyping protocol or one is not currently available.
Helpful Links
Genotyping resources and troubleshooting
Smith BK; Andrews PK; West DB. 2000. Macronutrient diet selection in thirteen mouse strains. Am J Physiol Regul Integr Comp Physiol 278(4):R797-805. [PubMed: 10749765] [MGI Ref ID J:61602]
Staelens J; Puimege L; Mahieu T; Pynaert G; Hochepied T; Vandenabeele A; Grooten J; Kontoyiannis D; Van Roy F; Kollias G; Libert C. 2004. Response of TNF-hyporesponsive SPRET/Ei mice in models of inflammatory disorders. Mamm Genome 15(7):537-43. [PubMed: 15366373] [MGI Ref ID J:92307]
Staelens J; Wielockx B; Puimege L; Van Roy F; Guenet JL; Libert C. 2002. Hyporesponsiveness of SPRET/Ei mice to lethal shock induced by tumor necrosis factor and implications for a TNF-based antitumor therapy. Proc Natl Acad Sci U S A 99(14):9340-5. [PubMed: 12089334] [MGI Ref ID J:77727]
Animal Health Reports
Room Number A2A
Room Number MGL375/MGL377
Colony Maintenance
Mating System Sibling x Sibling (Female x Male)
| Pricing for USA, Canada and Mexico shipping destinations |
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Weeks of Age Price (US dollars $) Gender Individual Mouse $127.30 Female or Male
| Pricing for International shipping destinations |
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Weeks of Age Price (US dollars $) Gender Individual Mouse $165.50 Female or Male
| Standard Supply | Repository-Live. A collection of over 1000 strains maintained as live colonies. Individual colonies are sized to meet current customer demand. Delivery for orders of 10 mice or less ranges on average from one to eight weeks; mice are generally shipped between four to six weeks of age with a maximum shipping age of approximately nine weeks. Colony sizes do not generally support stringent age specifications for large volumes of mice; however custom orders and larger quantities of mice are easily arranged. Estimated ship dates for all orders provided within two business days following order placement. |
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| Supply Notes |
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Purchasing Information
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Contact Information
Orders & Technical Support
Tel: 1-800-422-6423 or 1-207-288-5845
Fax: 1-207-288-6150
Technical Support Email Form
| phone: | 207-288-6470 |
| fax: | 207-288-6655 |
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