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General Terms and Conditions

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Product Information

Strain Details

Type Inbred Strain Additional information on Inbred Strains. Type Wild-Derived Additional information on Wild-Derived Mice. Mating System Sibling x Sibling         (Female x Male) Species M. spretus (Spain) Generation F75 (01-DEC-06) Geographic Origin Puerto Real, Cadiz Province, Spain

Appearance
white-bellied agouti
Related Genotype: A^w/A^w

Strain Description
The wild-derived inbred strain SPRET/Ei is often used in crosses with common inbred strains to create highly polymorphic panels for genetic mapping. SPRET/Ei mice are resistant to high doses of tumor necrosis factor alpha (TNFa) (Staelens et al 2002). Mice from a C57BL/6 x SPRET/Ei F1 cross were protected from TNFa-induced arthritis and partially protected against induced allergic asthma (Staelens et al 2004). SPRET/Ei may be useful in understanding certain inflammatory diseases.

Phenotypic Data

Mouse Phenome Database
Mouse Phenome Database / SNP Facility

Additional Web Information

Genetic Quality Control Annual Report
JAX^® NOTES, Winter 1995; 460. Wild-Derived Mice Strains - Tips on Their Care and Handling.

Animal Health Reports

Room Number           A2A

Research Applications

This mouse can be used to support research in many areas including:

Immunology and Inflammation Research
Inflammation

Reproductive Biology Research
Fertility Defects (male progeny from outcrosses to inbred are sterile)

Research Tools
Genetics Research (Evolution and Systematics Research)
Genetics Research (Gene Mapping: Polymorphisms)

References

Additional References

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Price and Supply Information

Strain Name:	SPRET/EiJ
Stock Number:	001146

Price Details

IMPORTANT NOTE: Prices are based on shipping destination. To view prices, select your shipping destination.

• USA, Canada and Mexico
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Supply Details

Standard Supply	Repository-Live. A collection of over 1000 strains maintained as live colonies. Individual colonies are sized to meet current customer demand. Delivery for orders of 10 mice or less ranges on average from one to eight weeks; mice are generally shipped between four to six weeks of age with a maximum shipping age of ~nine weeks. Colony sizes do not generally support stringent age specifications for large volumes of mice; however custom orders and larger quantities of mice are easily arranged. Estimated ship dates for all orders provided within 48 hours of order placement.
Supply Notes	Usually shipped between four and eight weeks of age. This strain is included in the Mouse Mutant Resource collection. Genomic DNA is available for this strain from the Mouse DNA Resource.
Licensing	See General Terms and Conditions below

General Terms and Conditions

View JAX^® Mice & Services Conditions of Use.

The Jackson Laboratory's Genotype Promise

The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX^® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX^® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX^® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.

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Ordering and Purchasing Information

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Contact Information
Orders & Technical Support
Tel: 800.422.6423 or 207.288.5845
Fax: 207.288.6150
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