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Strain Name:

SPRET/EiJ

Stock Number:

001146

Availability:

Repository- Live


General Terms and Conditions


Product Information

Strain Details

Type Inbred Strain
Additional information on Inbred Strains.
Type Wild-Derived
Additional information on Wild-Derived Mice.
Mating SystemSibling x Sibling         (Female x Male)
SpeciesM. spretus (Spain)
GenerationF75 (01-DEC-06)
Geographic OriginPuerto Real, Cadiz Province, Spain

Appearance
white-bellied agouti
Related Genotype: Aw/Aw

Strain Description
The wild-derived inbred strain SPRET/Ei is often used in crosses with common inbred strains to create highly polymorphic panels for genetic mapping. SPRET/Ei mice are resistant to high doses of tumor necrosis factor alpha (TNFa) (Staelens et al 2002). Mice from a C57BL/6 x SPRET/Ei F1 cross were protected from TNFa-induced arthritis and partially protected against induced allergic asthma (Staelens et al 2004). SPRET/Ei may be useful in understanding certain inflammatory diseases.

Phenotypic Data

Mouse Phenome Database
Mouse Phenome Database / SNP Facility

Additional Web Information

Genetic Quality Control Annual Report
JAX® NOTES, Winter 1995; 460. Wild-Derived Mice Strains - Tips on Their Care and Handling.

Animal Health Reports

Room Number           A2A

Research Applications

This mouse can be used to support research in many areas including:

Immunology and Inflammation Research
Inflammation

Reproductive Biology Research
Fertility Defects (male progeny from outcrosses to inbred are sterile)

Research Tools
Genetics Research (Evolution and Systematics Research)
Genetics Research (Gene Mapping: Polymorphisms)

References

Additional References

Price and Supply Information

Strain Name: SPRET/EiJ
Stock Number: 001146

Price Details

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Supply Details

Standard SupplyRepository-Live. A collection of over 1000 strains maintained as live colonies. Individual colonies are sized to meet current customer demand. Delivery for orders of 10 mice or less ranges on average from one to eight weeks; mice are generally shipped between four to six weeks of age with a maximum shipping age of ~nine weeks. Colony sizes do not generally support stringent age specifications for large volumes of mice; however custom orders and larger quantities of mice are easily arranged. Estimated ship dates for all orders provided within 48 hours of order placement.
Supply Notes Usually shipped between four and eight weeks of age.
This strain is included in the Mouse Mutant Resource collection.
Genomic DNA is available for this strain from the Mouse DNA Resource.
LicensingSee General Terms and Conditions below  

General Terms and Conditions

View JAX® Mice & Services Conditions of Use.

The Jackson Laboratory's Genotype Promise

The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.
Ordering and Purchasing Information

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Contact Information
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Tel: 800.422.6423 or 207.288.5845
Fax: 207.288.6150
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