Strain Name: |
BALB/c-Krt71Ca-9J/J |
|---|---|
Stock Number: |
001274 |
Availability: | Repository-Cryopreserved |
General Terms and Conditions |
| Former Name |
BALB/c-Krt2-6gCa-9J/J (Changed: 21-JUL-06
) |
|
BALB/c-Krt2-6gCa-8J (Changed: 15-DEC-04
) | |
|
BALB/cBy-Ca9J/J (Changed: 15-DEC-04
) | |
| Genes & Alleles | Krt71; Krt71Ca-9J; |
Product Information
Strain Details
Type JAX® GEMM® Strain - Coisogenic Additional information on JAX® GEMM® Strains. Type JAX® GEMM® Strain - Mutant Strain Type JAX® GEMM® Strain - Spontaneous Mutation Species laboratory mouse Generation F23N1 (28-MAR-04) Strain Development
The Ca-9J allele of Krt71 arose spontaneously in a BALB/cBy histocompatibility mutant in 1988. Krt71Ca-9J was bred to homozygosity and maintained via sibling mating. In 1993 homozygotes at F24 were mated to generate embryos for cryopreservation. In 2003 recovery of these embryos proved difficult and thus recovered homozygotes were outcrossed to BALB/cByJ resulting in this BALB/c-Krt71Ca-9J strain.
Mammalian Phenotype Terms assigned by genotype |
Gene & Allele Details
| Allele Symbol | Krt71Ca-9J | ||
|---|---|---|---|
| Allele Name | caracul 9 Jackson | ||
| Strain of Origin | BALB/cBy | ||
| Gene Symbol and Name | Krt71, keratin 71 | ||
| Chromosome | 15 | ||
| Gene Common Name(s) | AA589543; Ca; Cu; K6IRS1; KRT6IRS; KRT6IRS1; Krt2-6g; MGC119390; MGC119391; caracul; curly; expressed sequence AA589543; keratin complex 2, basic, gene 6g; mK6irs; mK6irs1; | ||
| Molecular Note | Sequence analysis of Krt2-6g identified the spontaneous deletion of codon 140, comprised of nucleotides 418, 419, and 420 (CAA). The deleted codon predicted an asparagine in the alpha-helical rod domain. This molecular lesion is the same that has been identified in Krt2-6gCa-Rin, CaJ, and Ca10J. | ||
Related Strains
Strains carrying other alleles of Krt71
000124 B6.Cg-KitlSl Krt71Ca/J 000304 B6C3Fe a/a-Krt71Ca Scn8amed-J/J 001755 BALB/cBy-Krt71Ca-10J/J 000291 C3FeLe.Cg-a/a Hm KitlSl Krt71Ca-J/J View Strains carrying other alleles of Krt71 (4 strains)
Research Applications
This mouse can be used to support research in many areas including:Krt71Ca-9J related
Dermatology Research
Skin and Hair Texture Defects
References
Additional ReferencesPrice and Supply Information
| Strain Name: | BALB/c-Krt71Ca-9J/J |
| Stock Number: | 001274 |
Price Details
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Supply Details
| Standard Supply | Repository-Cryopreserved. Must Be Recovered. Please refer to pricing and supply notes for further information. |
|---|---|
| Supply Notes |
Cryopreserved Embryos This strain is also available as cryopreserved embryos from our Repository. Orders for cryopreserved embryos are supplied subject to a signed agreement that must be returned to the Customer Service Department after order placement. Experienced technicians at The Jackson Laboratory have recovered frozen embryos of this strain successfully. We will provide you enough embryos to perform two embryo transfers. The Jackson Laboratory does not guarantee successful recovery at your facility. For complete information on purchasing embryos from our repository, please visit our Cryopreserved Embryos web page. Cryorecovery - Standard. The recovery process begins when a signed agreement form is returned to the Customer Service Department after order placement. Although results vary by strain, at least two males and two females (two pairs) will be provided, typically within 15 weeks of our receipt of the signed agreement form. If the first recovery attempt is unsuccessful or only one pair is recovered, a second recovery will be done, extending the delivery time to approximately 25 weeks. At least one member of each pair will be of known genotype and will carry the mutation if it is a mutant strain. Please note that pairs may not reflect the mating scheme utilized by The Jackson Laboratory prior to cryopreservation of the strain. Mating schemes are sometimes modified for successful cryopreservation. Price represents a repository maintenance fee, which includes the cost of recovery of the strain from the cryopreservation resource and the periodic replacement of the frozen embryos used for recovery. Cryorecovery to establish a Dedicated Supply for greater quantities of mice. |
| Licensing | See General Terms and Conditions below |
General Terms and Conditions
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The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.Ordering and Purchasing Information
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