Strain Name: |
C57BL/6J-Bmp5se-4J/J |
|---|---|
Stock Number: |
001496 |
Availability: | Repository-Cryopreserved |
General Terms and Conditions |
| Genes & Alleles | Bmp5; Bmp5se-4J; |
Product Information
Strain Details
Type JAX® GEMM® Strain - Mutant Strain Additional information on JAX® GEMM® Strains. Type JAX® GEMM® Strain - Spontaneous Mutation Species laboratory mouse Generation F3+N1p Strain Development
The se-4J mutation in Bmp5 arose spontaneously at The Jackson Laboratory in 1987 in a backcross of C57BL/6J and B6.Cg-Otop1tlt which was then at N5. It was maintained by sibling mating and in1988 C57BL/6J females were bred with homozygous males then at F3 through F5 and the resulting embryos were cryopreserved.
Mammalian Phenotype Terms assigned by genotype |
Gene & Allele Details
| Allele Symbol | Bmp5se-4J | ||
|---|---|---|---|
| Allele Name | short ear 4 Jackson | ||
| Common Name(s) | Bmp5clv; | ||
| Strain of Origin | C57BL/6J-Otop1 | ||
| Gene Symbol and Name | Bmp5, bone morphogenetic protein 5 | ||
| Chromosome | 9 | ||
| Gene Common Name(s) | AU023399; MGC34244; expressed sequence AU023399; se; short ear; | ||
| Molecular Note | This allele was identified by a complementation test. Sequencing revealed a correctly spliced transcript with a G-to-A substitution at base 932 of the Bmp5 coding region. The G-to-A mutation changes the first arginine in the RXXR processing site to a glutamine. [MGI Ref ID J:136831] | ||
Related Strains
Strains carrying other alleles of Bmp5
000004 ABP/LeJ 000578 B6 x STOCK Tyrc-ch Bmp5se +/+ Myo6sv/J 000056 B6.Cg-Bmp5se/J 000285 B6.Cg-Rorasg + +/+ Myo5ad Bmp5se/J 005420 C;129S7 Gt(ROSA)26Sor-Bmp5cfe-se7J/J 005421 CBy;B6-Bmp5cfe-se8J/J 000253 DLS/LeJ 000644 SEA/GnJ 000270 SEC/1GnLeJ View Strains carrying other alleles of Bmp5 (9 strains)
Research Applications
This mouse can be used to support research in many areas including:Bmp5se-4J related
Developmental Biology Research
Growth Defects
Skeletal Defects
References
Additional ReferencesPrice and Supply Information
| Strain Name: | C57BL/6J-Bmp5se-4J/J |
| Stock Number: | 001496 |
Price Details
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Supply Details
| Standard Supply | Repository-Cryopreserved. Must Be Recovered. Please refer to pricing and supply notes for further information. |
|---|---|
| Supply Notes |
Cryorecovery - Standard. The recovery process begins when a signed agreement form is returned to the Customer Service Department after order placement. Although results vary by strain, at least two males and two females (two pairs) will be provided, typically within 15 weeks of our receipt of the signed agreement form. If the first recovery attempt is unsuccessful or only one pair is recovered, a second recovery will be done, extending the delivery time to approximately 25 weeks. At least one member of each pair will be of known genotype and will carry the mutation if it is a mutant strain. Please note that pairs may not reflect the mating scheme utilized by The Jackson Laboratory prior to cryopreservation of the strain. Mating schemes are sometimes modified for successful cryopreservation. Price represents a repository maintenance fee, which includes the cost of recovery of the strain from the cryopreservation resource and the periodic replacement of the frozen embryos used for recovery. Cryorecovery to establish a Dedicated Supply for greater quantities of mice. |
| Licensing | See General Terms and Conditions below |
General Terms and Conditions
View JAX® Mice & Services Conditions of Use.
The Jackson Laboratory's Genotype Promise
The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.Ordering and Purchasing Information
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