Strain Name: |
C57BL/6JEi-Chr YCB/EiJ |
|---|---|
Stock Number: |
001543 |
Availability: | Repository-Cryopreserved |
General Terms and Conditions |
| Genes & Alleles | Sry; SryCB; |
Product Information
Strain Details
Type Consomic Additional information on Consomic Mice. Species laboratory mouse Donating Investigator Eva Eicher, The Jackson Laboratory Generation N21 Strain Description
This YCB Chromosome on the C57BL/6J background results in Y-linked sex reversal wherein XYCB are frequently hermaphrodites. These hermaphrodites often do breed.Strain Development
Capanna et al. (Chromosoma, 1976 v58 p341) trapped feral mice in the town of Larino, in Campobasso Province, Italy and found that the resulting stock had a variety of Robertsonian translocations. The Y Chromosome from this CB stock was backcrossed onto the inbred C57BL/6JEi background resulting in this consomic strain. Thus, the autosomal translocations of the CB stock are not present in this consomic strain. Embryos were cryopreserved from matings of C57BL/6JEi females with consomic males at generation N20.
Mammalian Phenotype Terms assigned by genotype |
Gene & Allele Details
| Allele Symbol | SryCB | ||
|---|---|---|---|
| Allele Name | sex-determining region of Chr Y- CB | ||
| Gene Symbol and Name | Sry, sex determining region of Chr Y | ||
| Chromosome | Y | ||
| Gene Common Name(s) | SRYGENE; TDF; TDY; Tdf; Tdy; testis determining factor; testis determining-Y; | ||
Related Strains
Strains carrying other alleles of Sry
View Strains carrying other alleles of Sry (6 strains)
Research Applications
This mouse can be used to support research in many areas including:
Developmental Biology Research
Internal/Organ Defects (gonads)
Reproductive Biology Research
Developmental Defects Affecting Gonads
References
Selected Reference(s)
Capanna E; Gropp A; Winking H; Noack G; Civitelli MV. 1976. Robertsonian metacentrics in the mouse. Chromosoma 58(4):341-53. [PubMed: 1001158] [MGI Ref ID J:23091]
Eicher EM; Washburn LL; Whitney JB 3d; Morrow KE. 1982. Mus poschiavinus Y chromosome in the C57BL/6J murine genome causes sex reversal. Science 217(4559):535-7. [PubMed: 7089579] [MGI Ref ID J:6802]
Sage RD. 1981. Wild Mice., in The Mouse in Biomedical Research. In: History, Genetics and Wild Mice. Academic Press, New York. [MGI Ref ID J:133805]
Tucker PK; Lee BK; Eicher EM. 1989. Y chromosome evolution in the subgenus Mus (genus Mus). Genetics 122(1):169-79. [PubMed: 2543607] [MGI Ref ID J:9833]
Price and Supply Information
| Strain Name: | C57BL/6JEi-Chr YCB/EiJ |
| Stock Number: | 001543 |
Price Details
IMPORTANT NOTE: Prices are based on shipping destination. To view prices, select your shipping destination.
*NO Shipping Destination selected!
Supply Details
| Standard Supply | Repository-Cryopreserved. Must Be Recovered. Please refer to pricing and supply notes for further information. |
|---|---|
| Supply Notes |
Cryorecovery - Standard. The recovery process begins when a signed agreement form is returned to the Customer Service Department after order placement. Although results vary by strain, at least two males and two females (two pairs) will be provided, typically within 15 weeks of our receipt of the signed agreement form. If the first recovery attempt is unsuccessful or only one pair is recovered, a second recovery will be done, extending the delivery time to approximately 25 weeks. At least one member of each pair will be of known genotype and will carry the mutation if it is a mutant strain. Please note that pairs may not reflect the mating scheme utilized by The Jackson Laboratory prior to cryopreservation of the strain. Mating schemes are sometimes modified for successful cryopreservation. Price represents a repository maintenance fee, which includes the cost of recovery of the strain from the cryopreservation resource and the periodic replacement of the frozen embryos used for recovery. Cryorecovery to establish a Dedicated Supply for greater quantities of mice. |
| Licensing | See General Terms and Conditions below |
General Terms and Conditions
View JAX® Mice & Services Conditions of Use.
The Jackson Laboratory's Genotype Promise
The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.Ordering and Purchasing Information
Purchasing Information
JAX® Mice Orders
Surgical Services
Contact Information
Orders & Technical Support
Tel: 800.422.6423 or 207.288.5845
Fax: 207.288.6150
Technical Support Email Form