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- Description
- Phenotype
- Genes & alleles
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Description
Strain Information
Former Names AXB-8/PgnJ (Changed: 15-DEC-04 ) Type Recombinant Inbred (RI); Additional information on Recombinant Inbred Mice. Visit our online Nomenclature tutorial. Mating System Sibling x Sibling (Female x Male) 01-MAR-06 Species laboratory mouse RI progenitor A/J C57BL/6J H2 Haplotype a Generation F52p+F7 (06-JAN-09)
Generation DefinitionsAppearance
brown
Related Genotype: a/a Tyrp1b/Tyrp1b Tyr+/Tyr+Description
The AXB and BXA set of RI strains are useful in the genetic analysis of several complex diseases including cardiovascular disease, diabetes, cancer, cleft palate, and hydrocephalus. The individual strains within the RI set also differ in their susceptibility to infectious diseases and in their responses to alcohol, stress, and endotoxin. The strain distribution pattern (SDP) for both the AXB and BXA RI strains is available through the Mouse Genome Informatics Recombinant Inbred Strain Distribution Patterns Query FormDevelopment
The AXB and BXA recombinant inbred (RI) set of strains were originally generated and maintained at the University of California, San Diego, and have been imported into The Jackson Laboratory. There were originally 51 AXB and BXA strains derived from the C57BL/6J (Stock No. 000664) and A/J (Stock No. 000646) progenitor strains. Many of the original strains are either extinct or were discarded due to genetic contamination. Please refer to Sampson et al., 1998 for more information.
Related Strains
AXB Strains
001673 AXB1/PgnJ 001681 AXB10/PgnJ 001683 AXB12/PgnJ 001826 AXB13/PgnJ 001684 AXB13a/PgnJ 001685 AXB15/PgnJ 001687 AXB19/PgnJ 001686 AXB19a/PgnJ 001688 AXB19b/PgnJ 001674 AXB2/PgnJ 001690 AXB23/PgnJ 001691 AXB24/PgnJ 001676 AXB4/PgnJ 001677 AXB5/PgnJ 001678 AXB6/PgnJ View AXB Strains (15 strains)
Additional Web Information
JAX® NOTES, Spring 1996; 465. AXB/BXA Recombinant Inbred Strains.
Phenotype
Phenotype Information
Mouse Phenome Database
Wellcome Trust Centre for Human Genetics: Mouse Recombinant Inbred Line (RIL) Genotype Data for AXB RI Line
This mouse can be used to support research in many areas including:
Neurobiology Research
Behavioral and Learning Defects
genes regulating preferences to alcohol and stress
Research Tools
Cardiovascular Research
Diabetes and Obesity Research
Genetics Research
Gene Mapping: Tools for QTL Mapping, Segregation and Linkage Analysis
Immunology and Inflammation Research
genes regulating susceptibility to infectious disease and endotoxin
Genes & Alleles
Gene & Allele Information
Currently there are no related genes or alleles for this strain.Genotyping
Genotyping Information
This strain will not have a genotyping protocol or one is not currently available.Helpful Links
Genotyping resources and troubleshooting
References
References
Additional References
Brodkin ES; Carlezon WA Jr; Haile CN; Kosten TA; Heninger GR ; Nestler EJ. 1998. Genetic analysis of behavioral, neuroendocrine, and biochemical parameters in inbred rodents: initial studies in Lewis and Fischer 344 rats and in A/J and C57BL/6J mice. Brain Res 805(1-2):55-68. [PubMed: 9733917] [MGI Ref ID J:50636]
Gill K; Desaulniers N; Desjardins P; Lake K. 1998. Alcohol preference in AXB/BXA recombinant inbred mice: gender differences and gender-specific quantitative trait loci. Mamm Genome 9(12):929-35. [PubMed: 9880655] [MGI Ref ID J:52467]
Marshall JD; Mu JL; Cheah YC; Nesbitt MN; Frankel WN; Paigen B. 1992. The AXB and BXA set of recombinant inbred mouse strains. Mamm Genome 3(12):669-80. [PubMed: 1477475] [MGI Ref ID J:3516]
Mu JL; Naggert JK; Nishina PM; Cheah YC; Paigen B. 1993. Strain distribution pattern in AXB and BXA recombinant inbred strains for loci on murine chromosomes 10, 13, 17, and 18. Mamm Genome 4(3):148-52. [PubMed: 8094988] [MGI Ref ID J:4133]
Sampson SB; Higgins DC; Elliot RW; Taylor BA; Lueders KK; Koza RA; Paigen B. 1998. An edited linkage map for the AXB and BXA recombinant inbred mouse strains. Mamm Genome 9(9):688-94. [PubMed: 9716653] [MGI Ref ID J:45463]
Health & husbandry
Health & Colony Maintenance Information
Animal Health Reports
Room Number AX12
Colony Maintenance
Mating System Sibling x Sibling (Female x Male) 01-MAR-06 Diet Information LabDiet® 5K52/5K67
Purchasing information
Pricing, Supply Level & Notes, Controls
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Live Mice
Price (US dollars $) Gender Individual Mouse $88.00 Female or Male Standard Supply
Repository-Live. A collection of over 1000 strains maintained as live colonies. Individual colonies are sized to meet current customer demand. Delivery for orders of 10 mice or less ranges on average from one to eight weeks; mice are generally shipped between four to six weeks of age with a maximum shipping age of approximately nine weeks. Colony sizes do not generally support stringent age specifications for large volumes of mice; however custom orders and/or larger quantities of mice may be possible. Estimated ship dates for all orders provided within two business days following order placement.
Supply Notes
- Usually shipped between four and six weeks of age.
| Pricing for International shipping destinations |
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Live Mice
Price (US dollars $) Gender Individual Mouse $114.40 Female or Male Standard Supply
Repository-Live. A collection of over 1000 strains maintained as live colonies. Individual colonies are sized to meet current customer demand. Delivery for orders of 10 mice or less ranges on average from one to eight weeks; mice are generally shipped between four to six weeks of age with a maximum shipping age of approximately nine weeks. Colony sizes do not generally support stringent age specifications for large volumes of mice; however custom orders and/or larger quantities of mice may be possible. Estimated ship dates for all orders provided within two business days following order placement.
Supply Notes
- Usually shipped between four and six weeks of age.
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Standard Supply
Repository-Live. A collection of over 1000 strains maintained as live colonies. Individual colonies are sized to meet current customer demand. Delivery for orders of 10 mice or less ranges on average from one to eight weeks; mice are generally shipped between four to six weeks of age with a maximum shipping age of approximately nine weeks. Colony sizes do not generally support stringent age specifications for large volumes of mice; however custom orders and/or larger quantities of mice may be possible. Estimated ship dates for all orders provided within two business days following order placement.
General Supply Notes
- This strain is included in the Special Mutant Stock Resource collection.
- Genomic DNA is available for this strain from the Mouse DNA Resource.
Payment Terms and Conditions
Terms are granted by individual review and stated on the customer invoice(s) and account statement. These transactions are payable in U.S. currency within the granted terms. Payment for services, products, shipping containers, and shipping costs that are rendered are expected within the payment terms indicated on the invoice or stated by contract. Invoices and account balances in arrears of stated terms may result in The Jackson Laboratory pursuing collection activities including but not limited to outside agencies and court filings.
See Terms of Use tab for General Terms and Conditions
The Jackson Laboratory's Genotype Promise
The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.Ordering and Purchasing Information
Purchasing Information
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Tel: 1-800-422-6423 or 1-207-288-5845
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JAX® Mice, Products & Services Conditions of Use
"MICE" means mouse strains, their progeny derived by inbreeding or crossbreeding, unmodified derivatives from mouse strains or their progeny supplied by The Jackson Laboratory ("JACKSON"). "PRODUCTS" means biological materials supplied by JACKSON, and their derivatives. "RECIPIENT" means each recipient of MICE, PRODUCTS, or services provided by JACKSON including each institution, its employees and other researchers under its control. MICE or PRODUCTS shall not be: (i) used for any purpose other than the internal research, (ii) sold or otherwise provided to any third party for any use, or (iii) provided to any agent or other third party to provide breeding or other services. Acceptance of MICE or PRODUCTS from JACKSON shall be deemed as agreement by RECIPIENT to these conditions, and departure from these conditions requires JACKSON's prior written authorization.No Warranty
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