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Strain Name:

C3A.BLiA-Pde6b+.O20-Prph2Rd2/J

Stock Number:

001979

Availability:

Repository- Live


Link to main datasheet for 001979

Additional References

 

Agarwal N. 1994. Diurnal expression of NGF1-A mRNA in retinal degeneration slow (rds) mutant mouse retina. FEBS Lett 339(3):253-7. [PubMed: 8112464]  [MGI Ref ID J:16898]

Agarwal N; Jomary C; Jones SE; O'Rourke K; Chaitin M; Wordinger RJ; Murphy BF. 1996. Immunocytochemical colocalization of clusterin in apoptotic photoreceptor cells in retinal degeneration slow rds mutant mouse retinas. Biochem Biophys Res Commun 225(1):84-91. [PubMed: 8769098]  [MGI Ref ID J:34976]

Agarwal N; Nir I; Papermaster DS. 1994. Loss of diurnal arrestin gene expression in rds mutant mouse retinas. Exp Eye Res 58(1):1-8. [PubMed: 8157095]  [MGI Ref ID J:28768]

Ali RR; Reichel MB; Kanuga N; Munro PM; Alexander RA; Clarke AR; Luthert PJ; Bhattacharya SS; Hunt DM. 1998. Absence of p53 delays apoptotic photoreceptor cell death in the rds mouse. Curr Eye Res 17(9):917-23. [PubMed: 9746439]  [MGI Ref ID J:111968]

Ali RR; Sarra GM; Stephens C; Alwis Md; Bainbridge JW; Munro PM; Fauser S; Reichel MB; Kinnon C; Hunt DM; Bhattacharya SS; Thrasher AJ. 2000. Restoration of photoreceptor ultrastructure and function in retinal degeneration slow mice by gene therapy Nat Genet 25(3):306-10. [PubMed: 10888879]  [MGI Ref ID J:63124]

Anderson RE; Maude MB; Bok D. 2001. Low docosahexaenoic acid levels in rod outer segment membranes of mice with rds/peripherin and P216L peripherin mutations. Invest Ophthalmol Vis Sci 42(8):1715-20. [PubMed: 11431433]  [MGI Ref ID J:70247]

Cayouette M; Behn D; Sendtner M; Lachapelle P; Gravel C. 1998. Intraocular gene transfer of ciliary neurotrophic factor prevents death and increases responsiveness of rod photoreceptors in the retinal degeneration slow mouse. J Neurosci 18(22):9282-93. [PubMed: 9801367]  [MGI Ref ID J:50901]

Cayouette M; Smith SB; Becerra SP; Gravel C. 1999. Pigment epithelium-derived factor delays the death of photoreceptors in mouse models of inherited retinal degenerations. Neurobiol Dis 6(6):523-32. [PubMed: 10600408]  [MGI Ref ID J:59343]

Chaitin MH; Ankrum MT; Wortham HS. 1996. Distribution of CD44 in the retina during development and the rds degeneration. Brain Res Dev Brain Res 94(1):92-8. [PubMed: 8816281]  [MGI Ref ID J:33822]

Chang B; Hawes NL; Hurd RE; Davisson MT; Nusinowitz S; Heckenlively JR. 2002. Retinal degeneration mutants in the mouse. Vision Res 42(4):517-25. [PubMed: 11853768]  [MGI Ref ID J:75095]

Chang B; Heckenlively JR; Hawes NL; Roderick TH. 1993. New mouse primary retinal degeneration (rd-3). Genomics 16(1):45-9. [PubMed: 8486383]  [MGI Ref ID J:4367]

Cheng T; Peachey NS; Li S; Goto Y; Cao Y; Naash MI. 1997. The effect of peripherin/rds haploinsufficiency on rod and cone photoreceptors. J Neurosci 17(21):8118-28. [PubMed: 9334387]  [MGI Ref ID J:43692]

Conley S; Nour M; Fliesler SJ; Naash MI. 2007. Late-onset cone photoreceptor degeneration induced by R172W mutation in Rds and partial rescue by gene supplementation. Invest Ophthalmol Vis Sci 48(12):5397-407. [PubMed: 18055786]  [MGI Ref ID J:132515]

Connell G; Bascom R; Molday L; Reid D; McInnes RR; Molday RS. 1991. Photoreceptor peripherin is the normal product of the gene responsible for retinal degeneration in the rds mouse. Proc Natl Acad Sci U S A 88(3):723-6. [PubMed: 1992463]  [MGI Ref ID J:10978]

Ding XQ; Nour M; Ritter LM; Goldberg AF; Fliesler SJ; Naash MI. 2004. The R172W mutation in peripherin/rds causes a cone-rod dystrophy in transgenic mice. Hum Mol Genet 13(18):2075-87. [PubMed: 15254014]  [MGI Ref ID J:92815]

Ekstrom P; Sanyal S; Narfstrom K; Chader GJ; van Veen T. 1988. Accumulation of glial fibrillary acidic protein in Muller radial glia during retinal degeneration. Invest Ophthalmol Vis Sci 29(9):1363-71. [PubMed: 3417421]  [MGI Ref ID J:27850]

Farjo R; Fliesler SJ; Naash MI. 2007. Effect of Rds abundance on cone outer segment morphogenesis, photoreceptor gene expression, and outer limiting membrane integrity. J Comp Neurol 504(6):619-30. [PubMed: 17722028]  [MGI Ref ID J:131880]

Farjo R; Skaggs JS; Nagel BA; Quiambao AB; Nash ZA; Fliesler SJ; Naash MI. 2006. Retention of function without normal disc morphogenesis occurs in cone but not rod photoreceptors. J Cell Biol 173(1):59-68. [PubMed: 16585269]  [MGI Ref ID J:107832]

Fletcher RT; Sanyal S; Krishna G; Aguirre G; Chader GJ. 1986. Genetic expression of cyclic GMP phosphodiesterase activity defines abnormal photoreceptor differentiation in neurological mutants of inherited retinal degeneration. J Neurochem 46(4):1240-5. [PubMed: 3005510]  [MGI Ref ID J:12044]

Franke H; Klimke K; Brinckmann U; Grosche J; Francke M; Sperlagh B; Reichenbach A; Liebert UG; Illes P. 2005. P2X(7) receptor-mRNA and -protein in the mouse retina; changes during retinal degeneration in BALBCrds mice. Neurochem Int 47(4):235-42. [PubMed: 15964665]  [MGI Ref ID J:103892]

Gao H; Hollyfield JG. 1996. Basic fibroblast growth factor: increased gene expression in inherited and light-induced photoreceptor degeneration. Exp Eye Res 62(2):181-9. [PubMed: 8698078]  [MGI Ref ID J:32161]

Hawes NL; Smith RS; Chang B; Davisson M; Heckenlively JR; John SW. 1999. Mouse fundus photography and angiography: a catalogue of normal and mutant phenotypes. Mol Vis 5:22. [PubMed: 10493779]  [MGI Ref ID J:59481]

Hawkins RK; Jansen HG; Sanyal S. 1985. Development and degeneration of retina in rds mutant mice: photoreceptor abnormalities in the heterozygotes. Exp Eye Res 41(6):701-20. [PubMed: 3830736]  [MGI Ref ID J:25582]

Heckenlively JR; Chang B; Erway LC; Peng C; Hawes NL; Hageman GS; Roderick TH. 1995. Mouse model for Usher syndrome: linkage mapping suggests homology to Usher type I reported at human chromosome 11p15. Proc Natl Acad Sci U S A 92(24):11100-4. [PubMed: 7479945]  [MGI Ref ID J:121993]

Hilgers J. 1979. Prph2<Rd2> - retinal degeneration-2 Mouse News Lett 60:38.  [MGI Ref ID J:65320]

Horio N; Kachi S; Hori K; Okamoto Y; Yamamoto E; Terasaki H; Miyake Y. 2001. Progressive change of optical coherence tomography scans in retinal degeneration slow mice. Arch Ophthalmol 119(9):1329-32. [PubMed: 11545639]  [MGI Ref ID J:115731]

Hughes EH; Schlichtenbrede FC; Murphy CC; Sarra GM; Luthert PJ; Ali RR; Dick AD. 2003. Generation of activated sialoadhesin-positive microglia during retinal degeneration. Invest Ophthalmol Vis Sci 44(5):2229-34. [PubMed: 12714665]  [MGI Ref ID J:83027]

Iandiev I; Biedermann B; Bringmann A; Reichel MB; Reichenbach A; Pannicke T. 2006. Atypical gliosis in Muller cells of the slowly degenerating rds mutant mouse retina. Exp Eye Res 82(3):449-57. [PubMed: 16154566]  [MGI Ref ID J:106873]

Jansen HG; Sanyal S. 1984. Development and degeneration of retina in rds mutant mice: electron microscopy. J Comp Neurol 224(1):71-84. [PubMed: 6715580]  [MGI Ref ID J:7415]

Jones BW; Watt CB; Frederick JM; Baehr W; Chen CK; Levine EM; Milam AH; Lavail MM; Marc RE. 2003. Retinal remodeling triggered by photoreceptor degenerations. J Comp Neurol 464(1):1-16. [PubMed: 12866125]  [MGI Ref ID J:84675]

Kedzierski W; Lloyd M; Birch DG; Bok D; Travis GH. 1997. Generation and analysis of transgenic mice expressing P216L-substituted rds/peripherin in rod photoreceptors. Invest Ophthalmol Vis Sci 38(2):498-509. [PubMed: 9040483]  [MGI Ref ID J:112440]

Kedzierski W; Nusinowitz S; Birch D; Clarke G; McInnes RR; Bok D; Travis GH. 2001. Deficiency of rds/peripherin causes photoreceptor death in mouse models of digenic and dominant retinitis pigmentosa. Proc Natl Acad Sci U S A 98(14):7718-23. [PubMed: 11427722]  [MGI Ref ID J:77309]

Krishnamoorthy R; Agarwal N; Chaitin MH. 2000. Upregulation of CD44 expression in the retina during the rds degeneration. Brain Res Mol Brain Res 77(1):125-30. [PubMed: 10814838]  [MGI Ref ID J:62192]

LaVail MW; Yasumura D; Matthes MT; Lau-Villacorta C; Unoki K; Sung CH; Steinberg RH. 1998. Protection of mouse photoreceptors by survival factors in retinal degenerations. Invest Ophthalmol Vis Sci 39(3):592-602. [PubMed: 9501871]  [MGI Ref ID J:46230]

Lohr HR; Kuntchithapautham K; Sharma AK; Rohrer B. 2006. Multiple, parallel cellular suicide mechanisms participate in photoreceptor cell death. Exp Eye Res 83(2):380-9. [PubMed: 16626700]  [MGI Ref ID J:116326]

Ma J; Norton JC; Allen AC; Burns JB; Hasel KW; Burns JL; Sutcliffe JG; Travis GH. 1995. Retinal degeneration slow (rds) in mouse results from simple insertion of a t haplotype-specific element into protein-coding exon II. Genomics 28(2):212-9. [PubMed: 8530028]  [MGI Ref ID J:28016]

Morrow EM; Furukawa T; Raviola E; Cepko CL. 2005. Synaptogenesis and outer segment formation are perturbed in the neural retina of Crx mutant mice. BMC Neurosci 6(1):5. [PubMed: 15676071]  [MGI Ref ID J:95886]

Nir I; Haque R; Iuvone PM. 2000. Diurnal metabolism of dopamine in dystrophic retinas of homozygous and heterozygous retinal degeneration slow (rds) mice Brain Res 884(1-2):13-22. [PubMed: 11082482]  [MGI Ref ID J:66055]

Nir I; Haque R; Iuvone PM. 2001. Regulation of cAMP by light and dopamine receptors is dysfunctional in photoreceptors of dystrophic retinal degeneration slow(rds) mice. Exp Eye Res 73(2):265-72. [PubMed: 11446777]  [MGI Ref ID J:70501]

Nir I; Iuvone PM. 1994. Alterations in light-evoked dopamine metabolism in dystrophic retinas of mutant rds mice. Brain Res 649(1-2):85-94. [PubMed: 7953658]  [MGI Ref ID J:18990]

Nir I; Kedzierski W; Chen J; Travis GH. 2000. Expression of Bcl-2 protects against photoreceptor degeneration in retinal degeneration slow (rds) mice. J Neurosci 20(6):2150-4. [PubMed: 10704489]  [MGI Ref ID J:60966]

Portera-Cailliau C; Sung CH; Nathans J; Adler R. 1994. Apoptotic photoreceptor cell death in mouse models of retinitis pigmentosa. Proc Natl Acad Sci U S A 91(3):974-8. [PubMed: 8302876]  [MGI Ref ID J:16708]

Rattner A; Chen J; Nathans J. 2004. Proteolytic shedding of the extracellular domain of photoreceptor cadherin. Implications for outer segment assembly. J Biol Chem 279(40):42202-10. [PubMed: 15284225]  [MGI Ref ID J:119370]

Robb RM. 1979. Cyclic nucleotide phosphodiesterase activity in normal mice and mice with retinal degeneration. Invest Ophthalmol Vis Sci 18(10):1097-100. [PubMed: 225287]  [MGI Ref ID J:6199]

Sanyal S; De Ruiter A; Hawkins RK. 1980. Development and degeneration of retina in rds mutant mice: light microscopy. J Comp Neurol 194(1):193-207. [PubMed: 7440795]  [MGI Ref ID J:6432]

Sanyal S; Fletcher R; Liu YP; Aguirre G; Chader G. 1984. Cyclic nucleotide content and phosphodiesterase activity in the rds mouse (020/A) retina. Exp Eye Res 38(3):247-56. [PubMed: 6327341]  [MGI Ref ID J:7447]

Sanyal S; Hawkins RK. 1986. Development and degeneration of retina in rds mutant mice: effects of light on the rate of degeneration in albino and pigmented homozygous and heterozygous mutant and normal mice. Vision Res 26(8):1177-85. [PubMed: 3798752]  [MGI Ref ID J:25584]

Sanyal S; Jansen HG. 1981. Absence of receptor outer segments in the retina of rds mutant mice. Neurosci Lett 21(1):23-6. [PubMed: 7207866]  [MGI Ref ID J:108107]

Stricker HM; Ding XQ; Quiambao A; Fliesler SJ; Naash MI. 2005. The Cys214-->Ser mutation in peripherin/rds causes a loss-of-function phenotype in transgenic mice. Biochem J 388(Pt 2):605-13. [PubMed: 15656787]  [MGI Ref ID J:104527]

Takeuchi K; Nakazawa M; Mizukoshi S. 2008. Systemic administration of nilvadipine delays photoreceptor degeneration of heterozygous retinal degeneration slow (rds) mouse. Exp Eye Res 86(1):60-9. [PubMed: 17976582]  [MGI Ref ID J:132513]

Travis GH; Bok D. 1993. Transgenic rescue of the photoreceptor dysplasia and degeneration in retinal degeneration slow (rds) mutant mice. Methods Neurosci 15:342-56.  [MGI Ref ID J:20399]

Travis GH; Brennan MB; Danielson PE; Kozak CA; Sutcliffe JG. 1989. Identification of a photoreceptor-specific mRNA encoded by the gene responsible for retinal degeneration slow (rds). Nature 338(6210):70-3. [PubMed: 2918924]  [MGI Ref ID J:9635]

Viczian A; Sanyal S; Toffenetti J; Chader GJ; Farber DB. 1992. Photoreceptor-specific mRNAs in mice carrying different allelic combinations at the rd and rds loci. Exp Eye Res 54(6):853-60. [PubMed: 1381682]  [MGI Ref ID J:2579]

Wong P; Borst DE; Farber D; Danciger JS; Tenniswood M; Chader GJ; van Veen T. 1994. Increased TRPM-2/clusterin mRNA levels during the time of retinal degeneration in mouse models of retinitis pigmentosa. Biochem Cell Biol 72(9-10):439-46. [PubMed: 7605616]  [MGI Ref ID J:24128]

Yang LP; Li Y; Zhu XA; Tso MO. 2007. Minocycline delayed photoreceptor death in rds mice through iNOS-dependent mechanism. Mol Vis 13:1073-82. [PubMed: 17653052]  [MGI Ref ID J:123401]

van Nie R; Ivanyi D; Demant P. 1978. A new H-2-linked mutation, rds, causing retinal degeneration in the mouse. Tissue Antigens 12(2):106-8. [PubMed: 705766]  [MGI Ref ID J:6051]

 

Link to main datasheet for 001979

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