Strain Name: |
129T2/SvEms |
|---|---|
Stock Number: |
002064 |
Availability: | Repository-Cryopreserved |
General Terms and Conditions |
| Genes & Alleles | Disc1; Disc1del; |
Product Information
Strain Details
Type Inbred Strain Additional information on Inbred Strains. Species laboratory mouse H2 Haplotype b Appearance
light-bellied agouti chinchilla
Related Genotype: Aw/Aw Tyrc-ch/Tyrc-ch
Gene & Allele Details
| Allele Symbol | Disc1del | ||
|---|---|---|---|
| Allele Name | deletion | ||
| Common Name(s) | Disc1129S6; | ||
| Strain of Origin | various | ||
| Gene Symbol and Name | Disc1, disrupted in schizophrenia 1 | ||
| Chromosome | 8 | ||
| Gene Common Name(s) | KIAA0457; SCZD9; | ||
| General Note | This deletion appears in multiple strains of the 129 superfamily. See J:111837 for details. This deletion has further been identified in the following strains:101/RI, BTBR T+ Tf/J and LP/J J:118317 | ||
| Molecular Note | A 25 bp deletion of the locus causes a frame shift in the reading frame, resulting in 13 novel amino acids and a premature stop codon at exon 7. [J:107244] | ||
Related Strains
129 Strains
001137 129P1/ReJ 000690 129P3/J 002357 129P3/JEmsJ 001198 129P4/RrRkJ 002448 129S1/SvImJ 002065 129T2/SvEmsJ 000691 129X1/SvJ View 129 Strains (7 strains)
001137 129P1/ReJ 000690 129P3/J 001198 129P4/RrRkJ 002448 129S1/SvImJ 002065 129T2/SvEmsJ 000691 129X1/SvJ 002282 BTBR T+ tf/J 000676 LP/J
Phenotypic Data
Festing Inbred Strain Characteristics: 129
Additional Web Information
New 129 Nomenclature Bulletin
Research Applications
This mouse can be used to support research in many areas including:
Cancer Research
Increased Tumor Incidence (Gonadal Tumors: testicular teratomas)
Reproductive Biology Research
Gonadal Tumors (testicular teratomas)
Research Tools
Genetics Research (Mutagenesis and Transgenesis: Production of Targeted Mutations ("Knockouts"))
References
Additional ReferencesPrice and Supply Information
| Strain Name: | 129T2/SvEms |
| Stock Number: | 002064 |
Price Details
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Supply Details
| Standard Supply | Repository-Cryopreserved. Must Be Recovered. Please refer to the Supply Notes for further information. |
|---|---|
| Supply Notes |
Cryorecovery - Standard. The recovery process begins when a signed agreement form is returned to the Customer Service Department after order placement. Although results vary by strain, at least two males and two females (two pairs) will be provided, typically within 15 weeks of our receipt of the signed agreement form. If the first recovery attempt is unsuccessful or only one pair is recovered, a second recovery will be done, extending the delivery time to approximately 25 weeks. At least one member of each pair will be of known genotype and will carry the mutation if it is a mutant strain. Please note that pairs may not reflect the mating scheme utilized by The Jackson Laboratory prior to cryopreservation of the strain. Mating schemes are sometimes modified for successful cryopreservation. Price represents a repository maintenance fee, which includes the cost of recovery of the strain from the cryopreservation resource and the periodic replacement of the frozen embryos used for recovery. Cryorecovery to establish a Dedicated Supply for greater quantities of mice. |
| Licensing | See General Terms and Conditions below |
General Terms and Conditions
View JAX® Mice & Services Conditions of Use.
The Jackson Laboratory's Genotype Promise
The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.Ordering and Purchasing Information
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