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Strain Name:

129T2/SvEms

Stock Number:

002064

Availability:

Repository-Cryopreserved


Price and Supply Information

General Terms and Conditions

Genes & Alleles   Disc1;   Disc1del;


Product Information

Strain Details

Type Inbred Strain
Additional information on Inbred Strains.
Specieslaboratory mouse
H2 Haplotypeb

Appearance
light-bellied agouti chinchilla
Related Genotype: Aw/Aw Tyrc-ch/Tyrc-ch

Gene & Allele Details

Allele Symbol Disc1del
Allele Name deletion
Common Name(s) Disc1129S6;
Strain of Originvarious
Gene Symbol and Name Disc1, disrupted in schizophrenia 1
Chromosome 8
Gene Common Name(s) C1orf136; FLJ13381; FLJ21640; FLJ25311; FLJ41105; KIAA0457; SCZD9;
General Note This deletion appears in multiple strains of the 129 superfamily. See J:111837 for details. This deletion has further been identified in the following strains:101/RI, BTBR T+ Tf/J and LP/J J:118317
Molecular Note A 25 bp deletion of the locus causes a frame shift in the reading frame, resulting in 13 novel amino acids and a premature stop codon at exon 7. [MGI Ref ID J:107244]

Related Strains

129 Strains
001137   129P1/ReJ
000690   129P3/J
002357   129P3/JEmsJ
001198   129P4/RrRkJ
002448   129S1/SvImJ
002065   129T2/SvEmsJ
000691   129X1/SvJ
View 129 Strains     (7 strains)

Strains carrying   Disc1del allele
001137   129P1/ReJ
000690   129P3/J
001198   129P4/RrRkJ
002448   129S1/SvImJ
002065   129T2/SvEmsJ
000691   129X1/SvJ
002282   BTBR T+ tf/J
000676   LP/J
View Strains carrying   Disc1del     (8 strains)

Phenotypic Data

Festing Inbred Strain Characteristics: 129

Additional Web Information

New 129 Nomenclature Bulletin

Research Applications

This mouse can be used to support research in many areas including:

Cancer Research
Increased Tumor Incidence (Gonadal Tumors: testicular teratomas)

Reproductive Biology Research
Gonadal Tumors (testicular teratomas)

Research Tools
Genetics Research (Mutagenesis and Transgenesis: Production of Targeted Mutations ("Knockouts"))

References

Additional References

Price and Supply Information

Strain Name: 129T2/SvEms
Stock Number: 002064

Price Details

IMPORTANT NOTE: Prices are based on shipping destination. The shipping destinations are:

*Pricing for Shipping Destination selected:

        International

Price(s) in US dollars ($)
Cryorecovery Fee $2470.00

Supply Details

Standard SupplyRepository-Cryopreserved. Must Be Recovered. Please refer to pricing and supply notes for further information.
Supply Notes Cryorecovery - Standard.
The recovery process begins when a signed agreement form is returned to the Customer Service Department after order placement. Although results vary by strain, at least two males and two females (two pairs) will be provided, typically within 15 weeks of our receipt of the signed agreement form. If the first recovery attempt is unsuccessful or only one pair is recovered, a second recovery will be done, extending the delivery time to approximately 25 weeks. At least one member of each pair will be of known genotype and will carry the mutation if it is a mutant strain. Please note that pairs may not reflect the mating scheme utilized by The Jackson Laboratory prior to cryopreservation of the strain. Mating schemes are sometimes modified for successful cryopreservation. Price represents a repository maintenance fee, which includes the cost of recovery of the strain from the cryopreservation resource and the periodic replacement of the frozen embryos used for recovery.

Cryorecovery to establish a Dedicated Supply for greater quantities of mice.
One to two pairs will be recovered to establish a Dedicated Supply of mice. Price by quotation. For more information on Dedicated Supply, please contact JAX® Services: Tel: 1-800-422-6423 or 1-207-288-5845; Email: jaxservices@jax.org.

LicensingSee General Terms and Conditions below  

General Terms and Conditions

View JAX® Mice & Services Conditions of Use.

The Jackson Laboratory's Genotype Promise

The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.
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Tel: 800.422.6423 or 207.288.5845
Fax: 207.288.6150
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